Biomarkers of cardiovascular disease risk in 40-65- Year-old men performing recommended levels of physical activity, compared with sedentary men

British Journal of Sports Medicine

Volumn 43, Issue 2, 2009, Pages 136-141

  Perkins, G M ^a   Owen, A ^b   Kearney, E M ^c   Swaine, I L ^a  

^a CANTERBURY CHRIST CHURCH UNIVERSITY   (United Kingdom)

^b KENT AND CANTERBURY HOSPITAL   (United Kingdom)

^c Queen Elizabeth the Queen Mother Hospital   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; APOLIPOPROTEINS; BIOLOGICAL MARKERS; CARDIOVASCULAR DISEASES; CHOLESTEROL; CROSS-SECTIONAL STUDIES; EXERCISE; HUMANS; MALE; MIDDLE AGED; RISK FACTORS; TRIGLYCERIDES;

EID: 61449194232     PISSN: 03063674     EISSN: 14730480     Source Type: Journal    
DOI: 10.1136/bjsm.2007.044420     Document Type: Article

References (36)

1. Warburton DE, Nicol CW, Bredin SS. Health benefits of physical activity: the evidence. Can Med Assoc J 2006;174:801-9.
2. Pate RR, Pratt M, Blair SN, et al. Physical activity and public health: a recommendation from the Centers for Disease Control and Prevention and the American College of Sports Medicine. JAMA 1995;273:402-7.
3. US Department of Health and Human Services. Physical Activity and Health. A report of the Surgeon General. Atlanta GA: US Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, 1996.
4. Thompson PD, Buchner D, Pina IL, et al. Exercise and physical activity in the prevention and treatment of atherosclerotic cardiovascular disease. A statement from the Council on Clinical Cardiology (Subcommittee on Exercise, Rehabilitation, and Prevention) and the Council on Nutrition, Physical Activity, and Metabolism (Subcommittee on Physical Activity). Circulation 2003;107:3109-16.
5. Chief Medical Officer's Annual Report. At least five a week: Evidence on the impact of physical activity and its relationship to health. London: Department of Health, 2004.
6. Haskell WL, Lee I-M, Pate RR et al. Physical activity and Public Health. Updated recommendations for adults from the American College of Sports Medicine and the American Heart Association. Circulation 2007;116:1081-93.
7. Durstine JL, Grandjean PW, Davis PG, et al. Blood lipids and lipoprotein adaptations to exercise. A quantitative analysis. Sports Med 2001;31:1033-62.
8. Kodama S, Tanaka S, Saito K, et al. Effect of aerobic exercise training on serum levels of high-density lipoprotein cholesterol. Arch Intern Med 2007;167:999-1008.
9. Walldius G, Jungner I, Holme I, et al. High apolipoprotein B, low apolipoprotein A-1, and improvement in the prediction of fatal myocardial infarction (AMORIS study): a prospective study. Lancet 2001;358:2026-33.
10. Walldius G, Jungner I. Apolipoprotein A-I versus HDL cholesterol in the prediction of risk for myocardial infarction and stroke. Curr Opin Cardiol 2007;22:359-67.
11. Meisinger C, Loewel H, Mraz W, et al. Prognostic value of apolipoprotein B and A-1 in the prediction of myocardial infarction in middle-aged men and women: results from the MONICA/KORA Ausburg cohort study. Eur Heart J 2005;26:271-8.
12. Walldius G, Junger I. Rationale for using apolipoprotein B and apolipoprotein A-1 as indicators of cardiac risk and as targets for lipid-lowering therapy. Eur Heart J 2005;26:210-12.
13. Friedewald WT, Levy RL, Fredrickson DS. Estimation of the concentration of low density lipoprotein cholesterol in plasma without use of the preparative ultracentrifuge. Clin Chem 1972;18:499.
14. Department of Health. British Heart Foundation Health Promotion Research Group. Coronary heart disease statistics. London: Department of Public Health, 2006.
15. Jousilahti P, Vartiainen E, Tuomilehto J, et al. Sex, age, cardiovascular risk factors, and coronary heart disease. A prospective follow-up study of 14 786 middle-aged men and women in Finland. Circulation 1999;99:1165-72.
16. Paffenbarger RS, Wing AL, Hyde RT. Physical activity as an index of heart attack risk in college alumni. Am J Epidemiol 1978;108:161-75.
17. Ainsworth B, Haskell W, Whitt M, et al. Compendium of physical activities: an update of activity codes and MET intensities. Med Sci Sports Exerc 2000;32(Suppl 9):S498-516.
18. Ainsworth B, Leon AS, Richardson MT, et al. Accuracy of the College Alumnus Physical Activity Questionnaire. J Clin Epidemiol 1993:46:1403-11.
19. Paffenbarger R, Blair S, Lee I, et al. Measurement of physical activity to assess health effects in free-living populations. Med Sci Sports Exerc 1993;25:60-70.
20. 2 during exercise in humans: the peak vs. maximum issue. J Appl Physiol 2003;95:1901-07.
21. O'Donovan G, Owen A, Kearney EM, et al. Cardiovascular disease risk factors in habitual exercisers, lean sedentary men and abdominally obese sedentary men. Int J Obesity 2005;29:1063-9.
22. Altman DG. Practical statistics for medical research. Boca Raton, FL: Chapman and Hall/CRC, 1990:455-60.
23. Lakka TA, Salonen JT. Physical activity and serum lipids: A cross-sectional population study in Eastern Finnish men. Am J Epidemiol 1993;136:806-18.
24. Pien H, Kao M. Correlation of blood lipids, lipoproteins and apolipoproteins with anthropometry in adult males. Nutrition 1996;12:737.
25. ACSM Position Stand: The recommended quantity and quality of exercise for developing and maintaining cardiorespiratory and muscular fitness, and flexibility in healthy adults. Med Sci Sports Exer 1998;30:975-91.
26. Kelley GA, Kelley KS, Tran ZV. Exercise, lipids, and lipoproteins in older adults: A meta-analysis. Prev Cardiol 2005;8:206-14.
27. Kelley GA, Kelley KS, Tran ZV. Exercise, lipids, and lipoproteins in older adults: a meta-analysis. Prev Cardiol 2005;8:206-14.
28. Carroll S, Dudfield M. What is the relationship between exercise and metabolic abnormalities? A review of the metabolic syndrome. Sports Med 2004;34:371-118.
29. Ferguson MA, Alderson NL, Trost, SG, et al. Effects of four different single exercise sessions on lipids, lipoproteins, and lipoprotein lipase. J Appl Physiol 1998;85:1169-74.
30. Grandjean PW, Crouse SF, Rohack JJ. Influence of cholesterol status on blood lipid and lipoprotein enzyme responses to aerobic exercise. J AppI Physiol 2000;89:472-80.
31. Lewis GF, Rader DJ. New insights into the regulation of HDL metabolism and reverse cholesterol transport. Circ Res 2005;96:1221-32.
32. Kiens B, Jorgensen I, Lewis S, et al. Increased plasma HDL-cholesterol and apo A-1 in sedentary middle-aged men after physical conditioning. Eur J Clin Invest 1980;10:203-9.
33. Lamarche B, Uffelman KD, Carpentier A, et al. Triglyceride enrichment of HDL enhances in vivo metabolic clearance of HDL apo A-1 in healthy men. J Clin Invest 1999;103:1191-9.
34. LaRosa JC, Hunninghake D, Bush D, et al. The cholesterol facts. A summary of the evidence relating dietary fats, serum cholesterol, and coronary heart disease. A joint statement by the American Heart Association and the National Heart, Lung, and Blood Institute. The Task Force on Cholesterol Issues, American Heart Association. Circulation 1990;81:1721-33.
35. Åstrand I. Aerobic work capacity in men and women with special reference to age. Acta Physiol Scand 1960;49:1-92.
36. MacWilliam JA. Postural effects on heart-rate and blood-pressure. Q J Exp Physiol 1933;23:1-33.