Raphanus sativus extract protects against Zearalenone induced reproductive toxicity, oxidative stress and mutagenic alterations in male Balb/c mice

Toxicon

Volumn 53, Issue 5, 2009, Pages 525-533

  Ben Salah Abbès, Jalila ^a   Abbès, Samir ^a   Abdel Wahhab, Mosaad A ^b   Oueslati, Ridha ^a  

^a University of Carthage   (Tunisia)

^b NATIONAL RESEARCH CENTRE   (Egypt)

Author keywords

DNA damage; Oxidative stress; Reproductive toxicity; Zearalenone

Indexed keywords

CATALASE; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; OLIVE OIL; PLANT EXTRACT; RAPHANUS SATIVUS EXTRACT; SUPEROXIDE DISMUTASE; TESTOSTERONE; UNCLASSIFIED DRUG; ZEARALENONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; GENOTOXICITY; GERM CELL; MALE; MOUSE; MUTAGENESIS; NONHUMAN; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RADISH; RANDOM AMPLIFIED POLYMORPHIC DNA; REPRODUCTIVE TOXICITY; SPERMATOZOON COUNT; TESTIS; TESTIS WEIGHT;

ANIMALS; CATALASE; MALE; MALONDIALDEHYDE; MICE; MICE, INBRED BALB C; MUTAGENESIS; ORGAN SIZE; OXIDATIVE STRESS; PLANT EXTRACTS; POLYMERASE CHAIN REACTION; PROTECTIVE AGENTS; RAPHANUS; REPRODUCTION; SPERM COUNT; SUPEROXIDE DISMUTASE; TESTIS; TESTOSTERONE; ZEARALENONE;

ANIMALIA; FUSARIUM; MUS; RAPHANUS SATIVUS;

EID: 61449184428     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2009.01.013     Document Type: Article

References (76)

1. Abbès S., Ouanas Z., Ben Salah-Abbès J., Houas Z., Oueslati R., Bacha H., and Othman O. The protective effect of hydrated sodium calcium aluminosilicate against haematological, biochemical and pathological changes induced by zearalenone in mice. Toxicon 47 (2006) 567-574
2. Abbès S., Ben Salah-Abbès J., Ouanes Z., Houas Z., Othman O., Bacha H., Abdel-Wahhab M.A., and Oueslati R. Preventive role of phyllosilicate clay on the immunological and biochemical toxicity of zearalenone in Balb/c mice. Int. Immunopharmacol. 6 (2006) 1251-1258
3. Abbès S., Ouanes Z., Ben Salah-Abbes J., Abdel-Wahha M.A., Oueslati R., and Bacha H. Preventive role of aluminosilicate clay against induction of micronuclei and chromosome aberrations in bone-marrow cells of Balb/c mice treated with Zearalenone. Mutat. Res. 631 (2007) 85-92
4. Abdel-Wahhab M.A., and Ahmed H.H. Protective effect of Korean Panax ginseng against chromium VI toxicity and free radical generation in rats. J. Ginseng Res. 28 (2004) 11-17
5. Abid-Essefi S., Baudrimont I., Hassen W., Ouanes Z., Mobio T.A., Ananeb R., Creppy E.E., and Bacha H. DNA fragmentation, apoptosis and cell cycle arrest induced by zearalenone in cultured DOK, Vero and Caco-2 cells: prevention by Vitamin E. Toxicology 192 (2003) 237-248
6. Abid-Essefi S., Ouanes Z., Hassen W., Baudrimont I., Creppy E.E., and Bacha H. Cytotoxicity, inhibition of DNA and protein syntheses and oxidative damage in cultured cells exposed to zearalenone. Toxicol. Vitro 18 (2004) 467-474
7. Aebi H. Catalase in vitro. Meth. Enzymol. 105 (1984) 121-126
8. Ban Y., Komatsu T., Kemi M., Inagaki S., Nakatsuka T., and Matsumoto H. Testicular spermatid and epididymal sperm head counts as an indicator for reproductive toxicity in rats. Exp. Anim. 44 (1995) 315-322
9. Barillari J., Cervellati R., Paolini M., Tatibouet A., Rollin P., and Iori R. Isolation of 4-methylthio-3-butenyl glucosinolate from Raphanus sativus L. sprouts (Kaiware-Daikon) and its redox properties. J. Agric. Food Chem. 53 (2005) 9890-9896
10. Ben Salah-Abbès J., Abbès S., Ouanes Z., Houas Z., Abdel-Wahhab M.A., Bacha H., and Oueslati R. Tunisian radish extract (Raphanus sativus) ameliorates the antioxidant status and mediates the oxidative stress of Zeralenone in Balb/c mice. J. Appl. Toxicol. 28 (2007) 6-14
11. Ben Salah-Abbès J., Abbès S., Houas Z., Abdel-Wahhab M.A., and Oueslati R. Zearalenone induces immunotoxicity in mice: possible protective effects of Radish extract (Raphanus Sativus). J. Pharm. Pharmacol. 60 (2008) 1-10
12. Biswas N.M., Sengupta R., Chatopadhyay G.R., Choudhury A., and Sarkar M. Effect of ethanol on cadmium-induced testicular toxicity in male rats. Reprod. Toxicol. 15 (2001) 699-704
13. Borutova R., Faix S., Placha I., Gresakova L., Cobanova K., and Leng L. Effects of deoxynivalenol and zearalenone on oxidative stress and blood phagocytic activity in broilers. Arch. Anim. Nutr. 62 (2008) 303-312
14. Council for Agricultural Science and Technology (CAST). Occurrence of mycotoxins in food and feed. In: CAST (Ed). Mycotoxins: Risks in Plant, Animal and Human Systems. Task Force Report No. 139 (2003), Council for Agricultural Science and Technology, Ames, IA 36-47
15. Chance B., Sies H., and Boveris A. Hydroperoxide metabolism in mammalian organs. Phys. Rev. 59 (1979) 527-605
16. Chiu B.C., Ji B.T., Dai Q., Gridley G., McLaughlin J.K., Gao Y.T., Fraumeni J.F.J., and Chow W.H. Dietary factors and risk of colon cancer in Shanghai, China. Cancer Epidemiol. Biomarkers Prev. 12 (2003) 201-208
17. Claus R., Hoang-Vu C., Ellendorff F., Meyer H.D., Schopper D., and Weiler U. Seminal oestrogens in the boar: origin and functions in the sow. J. Steroid Biochem. 27 (1987) 331-335
18. Conkova E., Laciakova A., Pastorova B., Seidel H., and Kovac G. The effect of zearalenone on some enzymatic parameters in rabbits. Toxicol Lett. 121 (2001) 145-149
19. Creppy E.E. Update of survey, regulation and toxic effects of mycotoxins in Europe. Toxicol. Lett. 124 (2002) 19-28
20. Cuénod A. Flore de la Tunisie: cryptogames vasculaires, gymnospermes et monocotylédones. Office de l'expérimentation de la vulgarisation agricoles de Tunisie. 2ème édition (1954), Elfarabi Press, Tunis 233-248
21. Dänicke S., Goyarts T., Döll S., Grove N., Spolders M., and Flachowsky G. Effects of the Fusarium toxin deoxynivalenol on tissue protein synthesis in pigs. Toxicol. Lett. 165 (2006) 297-311
22. Ebru B., and Mesut A. The effect of long-term supplemental dietary cadmium on lipid peroxidation and the antioxidant system in the liver and kidneys of rabbits. Turk. J. Vet. Anim. Sci. 26 (2002) 1055-1060
23. Ennamany R., Marzetto S., Saboureau D., and Creppy E.E. Lipid peroxidation induced by bolesatine, a toxin of Boletus satanas: implication in m5dC variation in Vero cells related to inhibition of cell growth. Cell Biol. Toxicol. 11 (1995) 347-354
24. Freund M., and Carol B. Factors affecting haemocytometer counts of sperm concentration in human semen. J. Reprod. Fertil. 42 (1964) 149-155
25. Fujii J., Iuchi Y., Matsuki S., and Ishii T. Cooperative function of antioxidant and redox systems against oxidative stress in male reproductive tissues. Asian J. Androl. 5 (2003) 231-242
26. Gill C.I., Haldar S., Porter S., Matthews S., Sullivan S., Coulter J., McGlynn H., and Rowland I. The effect of cruciferous and leguminous sprouts on genotoxicity, in vitro and in vivo. Cancer Epidemiol. Biomarkers Prev. 13 (2004) 1199-1205
27. Goodman G.E., Schaffer S., Ommen G.S., Chen C., and King K. The association between lung and prostate cancer risk, and serum micronutrients: results and lessons learned from â-carotene and retinol efficacy trial. Cancer Epidemiol. Biomarkers Prev. 12 (2003) 518-526
28. Grosse Y., Chekir-Ghedira L., Huc A., Obrecht-Pflumio S., Dirheimer G., Bacha H., and Pfohl-Leszkowicz A. Retinol, ascorbic acid and a-tocopherol prevent DNA adduct formation in mice treated with the mycotoxins ochratoxin A and zearalenone. Cancer Lett. 114 (1997) 225-229
29. Halliwell B. Free radicals, antioxidants, and human diseases: curiosity, cause or consequence?. Lancet 344 (1994) 721-724
30. Hashimoto T., Ueda Y., Oi N., Sakakibara H., Piao C., Ashida H., Goto M., and Kanazawa K. Effect of combined administration of quercetin, rutin, and extract of white radish sprout rich in kaempherol glucosides on the metabolism in rats. Biosci. Biotechnol. Biochem. 70 (2006) 279-281
31. Hassen W., Ayed-Boussema I., Oscoz A.A., De Cerain Lopez A.b., and Bacha H. The role of oxidative stress in zearalenone-mediated toxicity in Hep G2 cells: oxidative DNA damage, gluthatione depletion and stress proteins induction. Toxicology 232 (2007) 294-302
32. Hoppe P.C., and Pitts S. Fertilization in vitro and development of mouse ova. Biol. Reprod. 8 (1973) 420-426
33. IARC (International Agency for Research on Cancer). Some naturally occurring substances: food items and constituents, heterocyclic aromatic amines and mycotoxins. IARC Monographs on the Evaluations on the Carcinogenic Risk of Chemicals to Humans vol. 56 (1993), IARC, Lyon 397-444
34. IARC Handbooks of Cancer Prevention. Cruciferous Vegetables, Isothiocyanates and Indoles vol. 9 (2004), IARC Press, Lyon, France
35. Jaeschke H. Mechanisms of oxidant stress-induced acute tissue injury. Proc. Soc. Exp. Biol. Med. 209 (1995) 104-111
36. Jeffery E.H., and Jarrell V. Cruciferous vegetables and cancer prevention. In: Wildman R.E.C. (Ed). Handbook of Nutraceuticals and Functional Foods (2001), CRC Press, Boca Raton, FL 169-192
37. Kaneko T., Iuchi Y., and Kobayashi T. The expression of glutathione reductase in the male reproductive system of rats supports the enzymatic basis of glutathione function in spermatogenesis. Eur. J. Biochem. 269 (2002) 1570-1578
38. Katzenellenbogen B.S., Katzenellenbogen J.A., and Mordecai D. Zearalenones: characterization of the estrogenic potencies and receptor interactions of a series of fungal beta-resorcylic acid lactones. Endocrinology 105 (1979) 33-40
39. Keilin D., and Hartee E.F. Preparation of crystalline HRP. Meth. Enzymol. 2 (1951) 803-807
40. Kiang D.T., Kennedy B.J., Pathre S.V., and Mirocha C.J. Binding characteristics of zearalenone analogs to estrogen receptors. Cancer Res. 38 (1978) 3611-3615
41. Kim I.H., Son H.Y., Cho S.W., Ha C.S., and Kang B.H. Zearalenone induces male germ cell apoptosis in rats. Toxicol. Lett. 138 (2003) 185-192
42. Kouadio J., Dano S.D., Moukha S., Mobio T.A., and Creppy E.E. Effects of combinations of Fusarium mycotoxins on the inhibition of macromolecular synthesis, malondialdehyde levels, DNA methylation and fragmentation, and viability in Caco-2 cells. Toxicon 49 (2007) 306-317
43. Lee J., Richburg J.H., Younkin S.C., and Boekelheide K. The Fas system is a key regulator of germ cell apoptosis in the testis. Endocrinology 138 (1997) 2081-2088
44. Leffers H., Naesby M., Vendelbo B., Skakkebaek N.E., and Jorgensen M. Oestrogenic potencies of zeranol, oestradiol, diethylstilboestrol, Bisphenol-A and genistein: implications for exposure assessment of potential endocrine disrupters. Hum. Reprod. 16 (2001) 1037-1045
45. Liu S., Liu H., Yan W., Zhang L., Bai N., and Ho C. Design, synthesis, and anti-tumor activity of (2-O-alkyloxime-3-phenyl)-propionyl-1-O-acetyl britannil actone esters. Bioorg. Med. Chem. 13 (2005) 2783-2789
46. Luceri C., De Filippo C., Caderni G., Gambacciani L., Salvadori M., Giannini A., and Dolara P. Detection of somatic DNA alterations in azoxymethane-induced F344 rat colon tumors by random amplified polymorphic DNA analysis. Carcinogenesis 21 (2000) 1753-1756
47. Luo Y., Yoshizawa T., and Katayama T. Comparative study on the natural occurrence of Fusarium mycotoxins (trichothecenes and zearalenone) in corn and wheat from high- and low-risk areas for human esophageal cancer in China. Appl. Environ. Microbiol. 56 (1990) 3723-3726
48. Maral J., Puget K., and Michelson A.M. Comparative study of superoxide dismutase, catalase and glutathione peroxidase levels in erythrocytes of different animals. Biochem. Biophys. Res. Commun. 77 (1977) 1525-1535
49. Meki A.R., Esmail El.-D., Hussein A.A., and Hassanein H.M. Caspase-3 and heat shock protein-70 in rat liver treated with aflatoxin B1: effect of melatonin. Toxicon 43 (2004) 93-100
50. Paolotti F., and Mocali A. Determination of superoxide dismutase activity by purely chemical system based on NADPH oxidation. Meth. Enzymol. 186 (1990) 209-220
51. Pfohl-Leszkowicz A., Chekir-Ghedira L., and Bacha H. Genotoxicity of zearalenone, an oestrogenic mycotoxin: DNA adducts formation in female mouse tissues. Carcinogenesis 16 (1995) 2315-2320
52. Placer Z.A., Cushman L.L., and Johnson B.C. Estimation of product of lipid peroxidation (malonyldialdehyde) in biochemical systems. Anal. Biochem. 16 (1966) 359-364
53. Placinta C.M., D'Mello J.P.F., and Mac Donald A.M.C. A review of worldwide contamination of cereal grains and animal feed with Fusarium mycotoxins. Anim. Feed Sci. Technol. 78 (1999) 21-37
54. Prestera T., Zhang Y., Spencer S.R., Wilczak C.A., and Talalay P. The electrophile counterattack response: protection against neoplasia and toxicity. Adv. Enzym. Regul. 33 (1993) 281-296
55. Rago V., Siciliano L., Aquila S., and Carpino A. Detection of estrogen receptors ER-alpha and ER-beta in human ejaculated immature spermatozoa with excess residual cytoplasm. Reprod. Biol. Endocrinol. 4 (2006) 36-43
56. Rodriguez I., Ody C., Araki K., Garcia I., and Vassalli P. An early and massive wave of germinal cell apoptosis is required for the development of functional spermatogenesis. EMBO J. 16 (1997) 2262-2270
57. Ruhr L.P., Osweiler G.D., and Foley C.W. Effect of the estrogenic mycotoxin zearalenone on reproductive potential in the boar. Am. J. Vet. Res. 44 (1983) 483-485
58. Saenz de Rodriguez C.A., Bongiovanni A.M., and Conde de Borrego L. An epidemic of precocious development in Puerto Rican children. J. Pediatr. 107 (1985) 393-396
59. Sakai A., Suzuki C., Masui Y., Kuramashi A., Takatori K., and Tanaka N. The activities of mycotoxins derived from Fusarium and related substances in a short-term transformation assay using v-Ha-ras-transfected BALB/3T3 cells (Bhas 42 cells). Mutat. Res. 630 (2007) 103-111
60. Sambrook L., Fritsch E.F., and Manitatis T. Molecular Cloning: a Laboratory Manual (1989), Cold Spring Harbor Press, Cold Spring Harbor, NY
61. SAS Institute, Inc. SAS User's Guide: Statistics (1982), SAS Institute, Cary, N.C
62. Schoental R. Precocious sexual development in Puerto Rico and oestrogenic mycotoxins (zearalenone). Lancet 1 (1983) 537-543
63. Schollenberger M., Muller H.M., Rufle M., Suchy S., Plank S., and Drochner W. Natural occurrence of 16 Fusarium toxins in grains and feedstuffs of plant origin from Germany. Mycopathologia 161 (2006) 43-52
64. Shklar G. Mechanisms of cancer inhibition by antioxidant nutrients. Oral Oncol. l3 (1998) 424-429
65. Sipos P., Hagymasi K., Lugasi A., Feher E., and Blazovics A. Effects of black radish root (Raphanus sativus L. var niger) on the colonmucosa in rats fed a fat rich diet. Phytother. Res. 16 (2002) 677-679
66. Stabile V., Russo M., and Chieffi P. 17beta-estradiol induces Akt-1 through estrogen receptor-beta in the frog (Rana esculenta) male germ cells. Reproduction 132 (2006) 477-484
67. Stephan H., Polzar B., Rauch F., Zanotti S., Ulke C., and Mannherz H.G. Distribution of deoxyribonuclease I (DNase I) and p53 in rat testis and their correlation with apoptosis. Histochem. Cell Biol. 106 (1996) 383-393
68. Suda T., Takhashi T., Golstein P., and Nagata S. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 75 (1993) 1169-1178
69. Suh S.J., Moon S.K., and Kim C.H. Raphanus sativus and its isothiocyanates inhibit vascular smooth muscle cells proliferation and induce G1 cell cycle. Phytother. Res. Arrest Int. Immunopharmacol. 6 (2006) 854-861
70. Takaya Y., Kondo Y., Furukawa T., and Niwa M. Antioxidant constituents of radish sprout (Kaiware-Daikon), Raphanus sativus. J. Agric. Food Chem. 51 (2003) 8061-8066
71. Talalay P., and Fahey J.W. Phytochemicals from cruciferous plant protect against cancer by modulating carcinogen metabolism. J. Nutr. 131 (2001) 3027S-3033S
72. Tomaszewski J., Miturski R., Semczuk A., Kotarski J., and Jakowicki J. Tissue zearalenone concentration in normal, hyperplastic and neoplastic human endometrium. Ginekol. Pol. 69 (1998) 363-366
73. Waller R.A., and Duncan D.B. A Bayes rule for the symmetric multiple comparison problems. J. Am. Stat. Assoc. 641 (1969) 484-503
74. Wang L., Burhenne K., Kristensen B.K., and Rasmussen S.K. Purification and cloning of a Chinese red radish peroxidase that metabolise pelargonidin and forms a gene family in Brassicaceae. Gene 343 (2004) 323-335
75. Zinedine A., Soriano J.M., Moltó J.C., and Mañes J. Review on the toxicity, occurrence, metabolism, detoxification, regulations and intake of zearalenone: an oestrogenic mycotoxin. Food Chem. Toxicol. 45 (2007) 1-18
76. Zourgui L., El Golli E., Bouaziz C., Bacha H., and Hassen W. Cactus (Opuntia ficus-indica) cladodes prevent oxidative damage induced by the mycotoxin zearalenone in Balb/C mice. Food Chem. Toxicol. 46 (2008) 1817-1824