Reply to the discussion by Sergei V. Jargin on evaluation of cholesterol-lowering and antioxidant properties of sugar cane policosanols in hamsters and humans

Applied Physiology, Nutrition and Metabolism

Volumn 34, Issue 1, 2009, Pages 76-77

  Kassis, Amira N ^a   Marinangeli, Christopher P F ^a   Jones, Peter J H ^b  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY OF MANITOBA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 61449127217     PISSN: 17155312     EISSN: None     Source Type: Journal    
DOI: 10.1139/H08-140     Document Type: Note

References (11)

1. Berthold, H.K., Unverdorben, S., Degenhardt, R., Bulitta, M., and Gouni-Berthold, I. 2006. Effect of policosanol on lipid levels among patients with hypercholesterolemia or combined hyperlipidemia: a randomized controlled, trial. JAMA, 295: 2262-2269. doi:10.1001/jama.295.19.2262. PMID: 16705107.
2. Cubeddu, L.X., Cubeddu, R.J., Heimowitz, T., Restrepo, B., Lamas, G.A., and Weinberg, G.B. 2006. Comparative lipid-lowering effects of policosanol and atorvastatin: a randomized, parallel, double-blind, placebo-controlled trial. Am. Heart J. 152: 982.e1-982.e5. doi:10.1016/j.ahj.2006.08.009.
3. Dulin, M.F., Hatcher, L.F., Sasser, H.C., and Barringer, T.A. 2006. Policosanol is ineffective in the treatment of hypercholesterolemia: a randomized controlled trial. Am. J. Clin. Nutr. 84: 1543-1548. PMID:17158441.
4. Francini-Pesenti, F., Brocadello, F., Beltramolli, D., Nardi, M., and Caregaro, L. 2008. Sugar cane policosanol failed to lower plasma cholesterol in primitive, diet-resistant hypercholesterolaemia: a double blind, controlled study. Complement. Ther. Med. 16: 61-65. doi:10.1016/j.ctim.2007.08.003. PMID: 18514906.
5. Greyling, A., De Witt, C., Oosthuizen, W., and Jerling, J.C. 2006. Effects of a policosanol supplement on serum lipid concentrations in hypercholesterolaemic and heterozygous familial hypercholesterolaemic subjects. Br. J. Nutr. 95: 968-975. doi: 10. 1079/BJN20061715. PMID:16611388.
6. Kassis, A.N., and Jones, P.J. 2006. Lack of cholesterol-lowering efficacy of Cuban sugar cane policosanols in hypercholesterolemic persons. Am. J. Clin. Nutr. 84: 1003-1008. PMID:17093150.
7. Kassis, A.N., and Jones, P.J. 2008. Changes in cholesterol kinetics following sugar cane policosanol supplementation: a randomized control trial. Lipids Health Dis. 7: 17-25. doi:10.1186/1476-511X-7-17. PMID: 18447941.
8. Kassis, A.N., Marinangeli, C.P., Jain, D., Ebine, N., and Jones, P.J. 2007. Lack of effect of sugar cane policosanol on plasma cholesterol in Golden Syrian hamsters. Atherosclerosis, 194: 153-158. doi:10.1016/j. atherosclerosis.2006.10.008. PMID: 17123537.
9. Marinangeli, C.P., Kassis, A.N., Jain, D., Ebine, N., Cunnane, S.C., and Jones, P.J. 2007. Comparison of composition and absorption of sugarcane policosanols. Br. J. Nutr. 97: 381-388. doi:10. 1017/S0007114507336763. PMID: 17298709.
10. Nikitin, IuP., Slepchenko, N.V., Gratsianski?, N.A., Nechaev, A.S., Syrian, A.L., Poltavskaia, M.G., et al. 2000. Results of the multicenter controlled study of the hypolipidemic drug polycosanol in Russia. Ter. Arkh. 72: 7-10. PMID:11201841.
11. Prat, H., Román, O., and Pino, E. 1999. Comparative effects of policosanol and two HMG-CoA reductase inhibitors on type II hypercholesterolemia. Rev. Med. Chil. 127: 286-294. PMID: 10436712.