Gene amplification of Myc and its coamplification with ERBB2 and EGFR in gallbladder adenocarcinoma

Anticancer Research

Volumn 29, Issue 1, 2009, Pages 19-26

  Ooi, Akishi ^a,e   Suzuki, Shioto ^a   Nakazawa, Kumiko ^b   Itakura, Jun ^b   Imoto, Issei ^c   Nakamura, Hiroyuki ^a   Dobashi, Yoh ^d  

^a KANAZAWA UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCE   (Japan)

^b Hosei University   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^d JICHI MEDICAL UNIVERSITY   (Japan)

^e KANAZAWA UNIVERSITY   (Japan)

Author keywords

Adenocarcinoma; EGFR; ERBB2; Fluorescence in situ hybridization; Gallbladder; Gene amplification; Myc

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2;

ADULT; AGED; ARTICLE; CYTOGENETICS; DNA EXTRACTION; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GALLBLADDER CARCINOMA; GENE AMPLIFICATION; GENOMIC INSTABILITY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; ONCOGENE MYC; PRIORITY JOURNAL;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; FEMALE; GALLBLADDER NEOPLASMS; GENE AMPLIFICATION; GENES, MYC; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; MIDDLE AGED; NEOPLASM STAGING; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2;

EID: 61449126478     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Mai S and Mushinski JF: c-Myc-induced genomic instability. J Environ Pathol Toxicol Oncol 22: 179-199, 2003.
2. Yamamoto T, Ikawa S, Akiyama T, Semba K, Nomura N, Miyajima N, Saito T and Toyoshima K: Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor. Nature 319: 230-234, 1986.
3. Kobayashi M, Ooi A, Oda Y and Nakanishi I: Protein overexpression and gene amplification of c-erbB-2 in breast carcinomas: a comparative study of immunohistochemistry and fluorescence in situ hybridization of formalin-fixed, paraffin-embedded tissues. Hum Pathol 33: 21-28, 2002.
4. Takehana T, Kunitomo K, Kono K, Kitahara F, Iizuka H, Matsumoto Y, Fujino MA and Ooi A: Status of c-erbB-2 in gastric adenocarcinoma: a comparative study of immunohisto-chemistry, fluorescence in situ hybridization and enzyme-linked immunosorbent assay. Int J Cancer 98: 833-837, 2002.
5. Takehana T, Kunitomo K, Suzuki S, Kono K, Fujii H, Matsumoto Y and Ooi A: Expression of epidermal growth factor receptor in gastric carcinomas. Clin Gastroenterol Hepatol 1: 438-445, 2003.
6. Ooi A, Takehana T, Li X, Suzuki S, Kunitomo K, Iino H, Fujii H, Takeda Y and Dobashi Y: Protein overexpression and gene amplification of HER-2 and EGFR in colorectal cancers: an immunohistochemical and fluorescent in situ hybridization study. Mod Pathol 17: 895-904, 2004.
7. Hanawa M, Suzuki S, Dobashi Y, Yamane T, Kono K, Enomoto N and Ooi A: EGFR protein overexpression and gene amplification in squamous cell carcinomas of the esophagus. Int J Cancer 118: 1173-1180, 2006.
8. Hirashima N, Takahashi W, Yoshii S, Yamane T and Ooi A: Protein overexpression and gene amplification of c-erbB-2 in pulmonary carcinomas: a comparative immunohistochemical and fluorescence in situ hybridization study. Mod Pathol 14: 556-562, 2001.
9. Suzuki S, Dobashi Y, Sakurai H, Nishikawa K, Hanawa M and Ooi A: Protein overexpression and gene amplification of epidermal growth factor receptor in non-small cell lung carcinomas. Cancer 103: 1265-1273, 2005.
10. Nakazawa K, Dobashi Y, Suzuki S, Fujii H, Takeda Y and Ooi A: Amplification and overexpression of c-erbB-2, epidermal growth factor receptor, and c-met in biliary tract cancers. J Pathol 206: 356-365, 2005.
11. Mitsui F, Dobashi Y, Imoto I, Inazawa J, Kono K, Fujii H and Ooi A: Non-incidental coamplification of Myc and ERBB2, and Myc and EGFR, in gastric adenocarcinomas. Mod Pathol 20(6): 622-631, 2007.
12. Paterson AL, Pole JC, Blood KA, Garcia MJ, Cooke SL, Teschendorff AE, Wang Y, Chin SF, Ylstra B, Caldas C and Edwards PA: Co-amplification of 8p12 and 11q13 in breast cancers is not the result of a single genomic event. Genes Chromosomes Cancer 46: 427-439, 2007.
13. Hennson DE, Lawrence W and Klatt GR: Digestive sites. In: AJCC Cancer Staging Manual (5th edn), Flemming ID, Cooper JS and Henson DE (eds.). Philadelphia, Lippincott Williams and Wilkins: pp. 97-119, 1997.
14. Albores-Saavedral J, Scoazec JC, Wittekind C, Sripa B, Menck HR, Soehenda N and Siriam PVJ: Carcinoma of the gallbladder and extrahepatic bile duct. Hamilton SR, Aaltonen LA (eds.). In: World Health Organization Classification of Tumours. Tumours of the Digestive System. Lyon, IARCPress: pp. 206-214. 2000.
15. Landis JR and Koch GG: The measurement of observer agreement for categorical data. Biometrics 33: 159-174, 1977.
16. Cowell JK: Double minutes and homogeneously staining regions: gene amplification in mammalian cells. Annu Rev Genet 16: 21-59, 1982.
17. Coquelle A, Rozier L, Dutrillaux B and Debatisse M: Induction of multiple double-strand breaks within an hsr by meganucleaseI-SceI expression or fragile site activation leads to formation of double minutes and other chromosomal rearrangements. Oncogene 21: 7671-7679, 2002.
18. Hara T, Ooi A, Kobayashi M, Mai M, Yanagihara K and Nakanishi I: Amplification of c-myc, K-sam, and c-met in gastric cancers: detection by fluorescence in situ hybridization. Lab Invest 78: 1143-1153, 1998.
19. Mai S, Hanley-Hyde J and Fluri M: c-Myc overexpression associated DHFR gene amplification in hamster, rat, mouse and human cell lines. Oncogene 12: 277-288, 1996.
20. Hirsch FR, Varella-Garcia M, Bunn PA, Jr., Di Maria MV, Veve R, Bremmes RM, Baron AE, Zeng C and Franklin WA: Epidermal growth factor receptor in non-small cell lung carcinomas: correlation between gene copy number and protein expression and impact on prognosis. J Clin Oncol 21: 3798-3807, 2003.
21. Hirsch FR, Varella-Garcia M, Bunn PA Jr, Franklin WA, Dziadziuszko R, Thatcher N, Chang A, Parikh P, Pereira JR, Ciuleanu T, von Pawel J, Watkins C, Flannery A, Ellison G, Donald E, Knight L, Parums D, Botwood N and Holloway B: Molecular predictors of outcome with gefitinib in a phase III placebo-controlled study in advanced non-small cell lung cancer. J Clin Oncol 24: 5034-5042, 2006.
22. Rummukainen JK, Salminen T, Lundin J, Joensuu H and Isola JJ: Amplification of c-myc oncogene by chromogenic and fluorescence in situ hybridization in archival breast cancer tissue array samples. Lab Invest 81: 1545-1551, 2001.
23. Persons DL, Borelli KA and Hsu PH: Quantitation of HER-2/neu and c-myc gene amplification in breast carcinoma using fluorescence in situ hybridization. Mod Pathol 10: 720-727, 1997.
24. Park K, Kwak K, Kim J, Lim S and Han S: c-myc Amplification is associated with HER2 amplification and closely linked with cell proliferation in tissue microarray of nonselected breast cancers. Hum Pathol 36: 634-639, 2005.
25. Rodriguez-Pinilla SM, Jones RL, Lambros MB, Arriola E, Savage K, James M, Pinder SE and Reis-Filho JS: MYC amplification in breast cancer: a chromogenic in situ hybridisation study. J Clin Pathology 60: 1017-1023, 2007.
26. Kim C: Trastuzumab sensitivity of breast cancer with co-amplification of HER2 and cMyc in vivo. Breast Cancer Res Treat 54(Suppl 1): S6 (abstract), 2005.