Regulatory mechanism of transforming growth factor-beta 1 on mechanical properties of tissue engineered heart valve

Academic Journal of Second Military Medical University

Volumn 30, Issue 2, 2009, Pages 124-127

  Hong, Hao ^a   Dong, Nian Guo ^a   Shi, Jia Wei ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Collagen; Heart valve; Lysyl oxidase; Mechanical properties; Tissue engineering; Transforming growth factor beta 1

Indexed keywords

COLLAGEN TYPE 2; HYDROXYPROLINE; MESSENGER RNA; PROTEIN LYSINE 6 OXIDASE; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; CELL ISOLATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; GENE EXPRESSION; HEART VALVE; INCUBATION TIME; MECHANICAL STRESS; MYOFIBROBLAST; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REGULATORY MECHANISM; TISSUE ENGINEERING; YOUNG MODULUS;

EID: 61449106726     PISSN: 0258879X     EISSN: None     Source Type: Journal    
DOI: 10.3724/SP.J.1008.2009.00124     Document Type: Article

References (10)

1. Knight R L, Wilcox H E, Korossis S A, Fisher J, Ingham E. The use of acellular matrices for the tissue engineering of cardiac valves[J]. Proc Inst Mech Eng[H], 2008, 222:129-143.
2. Schoen J F. New frontiers in the pathology and therapy of heart valve disease:2006 Society for Cardiovascular Pathology, Distinguished Achievement Award Lecture, United States Canadian Academy of Pathology, Atlanta, GA, February 12, 2006[J]. Cardiovasc Pathol, 2006, 15:271-279.
3. Hopkins R A. Tissue engineering of heart valves:decellularized valve scaffolds[J]. Circulation, 2005, 111:2712-2714.
4. Narine K, De Wever O, Van Valckenborgh D, Francois K, Bracke M, DeSmet S, et al. Growth factor modulation of fibroblast proliferation, differentiation, and invasion: implications for tissue valve engineering[J]. Tissue Eng, 2006, 12: 2707-2716.
5. Chinese source.
6. Chinese source.
7. Chinese source.
8. Chinese source.
9. Schenke-Layland K, Opitz F, Gross M, Döring C, Halbhuber K J, Schirrmeister F, et al. Complete dynamic repopulation of decellularized heart valves by application of defined physical signals-an in vitro study[J]. Cardiovasc Res, 2003, 60:497-509.
10. Lau Y K, Gobin A M, West J L. Overexpression of lysyl oxidase to increase matrix crosslinking and improve tissue strength in dermal wound healing[J]. Ann Biomed Eng, 2006, 34: 1239-1246.