Mechanism of ionization of polycyclic aromatic hydrocarbons by a toluene/anisole mixture as a dopant in liquid chromatography/dopant-assisted atmospheric-pressure photoionization/mass spectrometry

Polycyclic Aromatic Compounds

Volumn 29, Issue 1, 2009, Pages 41-55

  Itoh, Nobuyasu ^a   Narukawa, Tomohiro ^a   Numata, Masahiko ^a   Aoyagi, Yoshie ^a   Yarita, Takashi ^a   Takatsu, Akiko ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

Anisole; Atmospheric pressure photoionization (APPI); Dopant assisted; Polycyclic aromatic hydrocarbons (PAHs); Toluene

Indexed keywords

ACETONITRILE; AROMATIZATION; ATMOSPHERIC IONIZATION; ATMOSPHERIC PRESSURE; CHARGE TRANSFER; CHROMATOGRAPHIC ANALYSIS; DOPING (ADDITIVES); LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHOTOIONIZATION; POLYCYCLIC AROMATIC HYDROCARBONS; POSITIVE IONS;

ANISOLE; ATMOSPHERIC PRESSURE PHOTO IONIZATION; ATMOSPHERIC-PRESSURE PHOTOIONIZATION; CLUSTER IONS; DOPANT ASSISTED; IONIZATION MECHANISMS; PHOTOIONIZATION MASS SPECTROMETRY; POLYCYCLIC AROMATIC HYDROCARBON; RADICAL CATIONS; REVERSED PHASE LIQUID-CHROMATOGRAPHY;

TOLUENE;

EID: 61449094863     PISSN: 10406638     EISSN: 15635333     Source Type: Journal    
DOI: 10.1080/10406630902720211     Document Type: Article

References (26)

1. Hanold, K.A., S. M. Fischer, P. H. Cormia, C. E. Miller, and J. A. Syage. 2004. Atmospheric pressure photoionization. 1. General properties for LC/MS. Anal. Chem. 76:2842-51.
2. Raffaelli, A., and A. Saba. 2003. Atmospheric pressure photoionization mass spectrometry. Mass Spectrom. Rev. 22:318-31.
3. Robb, D.B., and M. W. Blades. 2006. Factors affecting primary ionization in dopant-assisted atmospheric pressure photoionization (DA-APPI) for LC/MS. J. Am. Soc. Mass Spectr. 17:130-8.
4. Robb, D.B., and M. W. Blades. 2005. Effects of solvent flow, dopant flow, and lamp current on dopant-assisted atmospheric pressure photoionization (DA-APPI) for LC-MS. Ionization via proton transfer. J. Am. Soc. Mass Spectr. 16:1275-90.
5. Kauppila, T.J., R. Kostiainen, and A. P. Bruins. 2004. Anisole, a new dopant for atmospheric pressure photoionization mass spectrometry of low proton affinity, low ionization energy compounds. Rapid Commun. Mass Sp. 18:808-15.
6. Kauppila, T.J., T. Kuuranne, E. C. Meurer, M. N. Eberlin, T. Kotiaho, and R. Kostiainen. 2002. Atmospheric pressure photoionization mass spectrometry. Ionization mechanism and the effect of solvent on the ionization of naphthalenes. Anal. Chem. 74:5470-9.
7. Robb, D.B., T. R. Covey, and A. P. Bruins. 2000. Atmospheric pressure photoionization: An ionization method for liquid chromatography-mass spectrometry. Anal. Chem. 72:3653-9.
8. Cormia, P.H., S. M. Fischer, and C. A. Miller. 2001. Analysis of polyaromatic hydrocarbons by atmospheric pressure photoionization LC/MS, Proceedings of the 49th ASMS Conference on Mass spectrometry and Allied Topics, Chicago, Illionis, May 27-31, 2001.
9. Short, L.C., S.-S. Cai, and J. A. Syage. 2007. APPI-MS: Effects of mobile phases and VUV lamps on the detection of PAH compounds. J. Am. Soc. Mass Sp. 18:589-99.
10. Itoh, N., Y. Aoyagi, and T. Yarita. 2006. Optimization of the dopant for the trace determination of polycyclic aromatic hydrocarbons (PAHs) by liquid chromatography/dopant-assisted atmospheric-pressure photoionization/mass spectrometry (LC/DA-APPI/MS). J. Chromatogr. A 1131:285-8.
11. Finlayson-Pitts, B.J., and J. N. Pitts Jr. 2000. Chemistry of the upper and lower atmosphere: Theory, experiments, and applications. London: Academic Press.
12. Golomb, D., E. Barry, G. Fisher, P. Varanusupakul, M. Koleda, and T. Rooney. 2001. Atmospheric deposition of polycyclic aromatic hydrocarbons near New England coastal waters. Atmos. Environ. 35:6245-58.
13. Carrera, G., P. Fernandez, R. M. Vilanova, and J. O. Grimalt. 2001. Persistent organic pollutants in snow from European high mountain areas. Atmos. Environ. 35:245-54.
14. Masclet, P., V. Hoyau, J.L. Jaffrezo, and H. Cachier. 2000. Polycyclic aromatic hydrocarbon deposition on the ice sheet of Greenland. Part I: superficial snow. Atmos. Environ. 34:3195-207.
15. Ohkouchi, N., K. Kawamura, and H. Kawahata. 1999. Distributions of three-to seven-ring polynuclear aromatic hydrocarbons on the deep sea floor in the Central Pacific. Environ. Sci. Technol. 33:3086-90.
16. Menzie, C.A., B. B. Potocki, and J. Santodonato. 1992. Exposure to carcinogenic PAHs in the environment. Environ. Sci. Technol. 26:1278-84.
17. Maher, W.A., and J. Aislabie. 1992. Polycyclic aromatic hydrocarbons in nearshore marine sediments of Australia. Sci. Total Environ. 112:143-64.
18. Luch, A. 2004. The carcinogenetic effects of polycyclic aromatic hydrocarbons. London: Imperial College Press.
19. Billiard, S.M., M. E. Hahn, D. G. Franks, R. E. Peterson, N. C. Bols, and P. V. Hodson. 2002. Binding of polycyclic aromatic hydrocarbons (PAHs) to teleost aryl hydrocarbon receptors (AHRs). Comp. Biochem. Phys. B. 133:55-68.
20. Machala, M., J. Vondráłek, L. Bláaha, M. Ciganek, and J. Neła. 2001. Aryl hydrocarbon receptor-mediated activity of mutagenic polycyclic aromatic hydrocarbons determined using in vitro receptor gene assay. Mutat. Res. 497:49-62.
21. Arcaro, K.F., P. W. O'Keefe, Y. Yang, W. Clayton, and J. F. Gierthy. 1999. Antiestrogenicity of environmental polycyclic aromatic hydrocarbons in human breast cancer cells. Toxicol. 133:115-27.
22. Titato, G.M., and F. M. Lanças. 2006. Optimization and validation of HPLC-UVDAD and HPLC-APCI-MS methodologies for the determination of selected PAHs in water samples. J. Chromatogr. Sci. 44:35-40.
23. van Leeuwen, S.M., H. Hayen, and U. Karst. 2004. Liquid chromatography-electrochemistry-mass spectrometry of polycyclic aromatic hydrocarbons. Anal. Bioanal. Chem. 378:917-25.
24. Airiau, C.Y., R. G. Brereton, and J. Crosby. 2001. High-performance liquid chromatography/electrospray tandem mass spectrometry of polycyclic aromatic hydrocarbons. Rapid Commun. Mass Sp. 15:135-40.
25. The NIST Chemistry WebBook. US Institute of Standards and Technology (NIST), Gaithersburg, MD, 2007. http://webbook.nist.gov.
26. Tubaro, M., E. Marotta, R. Seraglia, and P. Traldi. 2003. Atmospheric pressure photoionization mechanisms. 2. The case of benzene and toluene. Rapid Commun. Mass Sp. 17:2423-29.