-
2
-
-
0141518579
-
-
For several biologically active natural products containing cyclic spirolactam or hemiaminal structure, see the following examples. Massadine: (a) Nishimura, S, Matsunaga, S, Shibazaki, M, Suzuki, K, Furihata, K, van Soest, R. W. M, Fusetani, N Org. Lett. 2003, 5, 2255-2257
-
For several biologically active natural products containing cyclic spirolactam or hemiaminal structure, see the following examples. Massadine: (a) Nishimura, S.; Matsunaga, S.; Shibazaki, M.; Suzuki, K.; Furihata, K.; van Soest, R. W. M.; Fusetani, N Org. Lett. 2003, 5, 2255-2257.
-
-
-
-
3
-
-
0000879865
-
-
Azaspirene: b
-
Azaspirene: (b) Asami, Y.; Kakeya, H.; Onose, R.; Yoshida, A.; Matsuzaki, H.; Osada, H. Org. Lett. 2002, 4, 2845-2848.
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(2002)
Org. Lett
, vol.4
, pp. 2845-2848
-
-
Asami, Y.1
Kakeya, H.2
Onose, R.3
Yoshida, A.4
Matsuzaki, H.5
Osada, H.6
-
4
-
-
0033524887
-
-
Axinellamine: (c) Urban, S.; Leone, P. A.; Carroll, A. R.; Fechner, G. A.; Smith, J.; Hopper, J. N. A.; Quinn, R. J. J. Org. Chem. 1999, 64, 731-735.
-
Axinellamine: (c) Urban, S.; Leone, P. A.; Carroll, A. R.; Fechner, G. A.; Smith, J.; Hopper, J. N. A.; Quinn, R. J. J. Org. Chem. 1999, 64, 731-735.
-
-
-
-
5
-
-
61349114114
-
-
Pseurotin A: (d) Komagata, D.; Fujita, S.; Yamashita, N.; Saito, S.; Morino, T. J. Antibiot. 1996, 49, 958-959.
-
Pseurotin A: (d) Komagata, D.; Fujita, S.; Yamashita, N.; Saito, S.; Morino, T. J. Antibiot. 1996, 49, 958-959.
-
-
-
-
6
-
-
0025829101
-
-
Synerazol: e
-
Synerazol: (e) Ando, O.; Satake, H.; Nakajima, M.; Sato, A.; Nakamura, T.; Kinoshita, T.; Furuya, K.; Haneishi, T. J. Antibiot. 1991, 44, 382-389.
-
(1991)
J. Antibiot
, vol.44
, pp. 382-389
-
-
Ando, O.1
Satake, H.2
Nakajima, M.3
Sato, A.4
Nakamura, T.5
Kinoshita, T.6
Furuya, K.7
Haneishi, T.8
-
7
-
-
0037011216
-
-
Hughes, C. C.; Trauner, D. Angew. Chem., Int. Ed. 2002, 41, 4556-4559.
-
(2002)
Angew. Chem., Int. Ed
, vol.41
, pp. 4556-4559
-
-
Hughes, C.C.1
Trauner, D.2
-
8
-
-
0041701543
-
-
(a) Sakaguchi, K.; Higashino, M.; Ohfune, Y. Tetrahedron 2003, 59, 6647-6658.
-
(2003)
Tetrahedron
, vol.59
, pp. 6647-6658
-
-
Sakaguchi, K.1
Higashino, M.2
Ohfune, Y.3
-
9
-
-
20544453835
-
-
(b) Sakaguchi, K.; Yamada, T.; Ohfune, Y. Tetrahedron Lett. 2005, 46, 5009-5012.
-
(2005)
Tetrahedron Lett
, vol.46
, pp. 5009-5012
-
-
Sakaguchi, K.1
Yamada, T.2
Ohfune, Y.3
-
10
-
-
34247633037
-
-
(c) Sakaguchi, K.; Okada, T.; Yamada, T.; Ohfune, Y. Tetrahedron Lett. 2007, 48, 3925-3928.
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(2007)
Tetrahedron Lett
, vol.48
, pp. 3925-3928
-
-
Sakaguchi, K.1
Okada, T.2
Yamada, T.3
Ohfune, Y.4
-
11
-
-
0034973963
-
-
(a) Sakaguchi, K.; Suzuki, H.; Ohfune, Y. Chirality 2001, 13, 357-365.
-
(2001)
Chirality
, vol.13
, pp. 357-365
-
-
Sakaguchi, K.1
Suzuki, H.2
Ohfune, Y.3
-
12
-
-
0037033285
-
-
(b) Morimoto, Y.; Takanishi, M.; Kinoshita, T.; Sakaguchi, K.; Shibata, K. Chem. Commun. 2002, 42-43.
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(2002)
Chem. Commun
, pp. 42-43
-
-
Morimoto, Y.1
Takanishi, M.2
Kinoshita, T.3
Sakaguchi, K.4
Shibata, K.5
-
13
-
-
3242751892
-
-
(c) Sakaguchi, K.; Yamamoto, M.; Kawamoto, T.; Yamada, T.; Shinada, T.; Shimamoto, K.; Ohfune, Y. Tetrahedron Lett. 2004, 45, 5869-5872.
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(2004)
Tetrahedron Lett
, vol.45
, pp. 5869-5872
-
-
Sakaguchi, K.1
Yamamoto, M.2
Kawamoto, T.3
Yamada, T.4
Shinada, T.5
Shimamoto, K.6
Ohfune, Y.7
-
14
-
-
34250023769
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-
(d) Sakaguchi, K.; Yamamoto, M.; Watanabe, Y.; Ohfune, Y. Tetrahedron Lett. 2007, 48, 4821-4824.
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(2007)
Tetrahedron Lett
, vol.48
, pp. 4821-4824
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-
Sakaguchi, K.1
Yamamoto, M.2
Watanabe, Y.3
Ohfune, Y.4
-
15
-
-
33748826144
-
2-assisted dianionic enolate Claisen rearrangement of the N-protected α-amino acid allyl ester was originally developed by Kazmaier: Kazmaier, U
-
2-assisted dianionic enolate Claisen rearrangement of the N-protected α-amino acid allyl ester was originally developed by Kazmaier: Kazmaier, U. Angew. Chem., Int. Ed. Engl. 1994, 33, 998-999.
-
(1994)
Angew. Chem., Int. Ed. Engl
, vol.33
, pp. 998-999
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-
-
16
-
-
0025278992
-
-
(a) Sonderquist, E. J.; Anderson, C. L.; Miranda, E. I.; Rivera, I. Tetrahedron Lett. 1990, 31, 4677-4680.
-
(1990)
Tetrahedron Lett
, vol.31
, pp. 4677-4680
-
-
Sonderquist, E.J.1
Anderson, C.L.2
Miranda, E.I.3
Rivera, I.4
-
19
-
-
61349123432
-
-
Hydrogenation of 3 using the Lindlar catalyst did not give any olefin product even at high pressure (5 atm). The use of Pd/C produced the corresponding alkane.
-
Hydrogenation of 3 using the Lindlar catalyst did not give any olefin product even at high pressure (5 atm). The use of Pd/C produced the corresponding alkane.
-
-
-
-
20
-
-
61349198051
-
-
The absolute configuration of the minor isomer was not determined
-
The absolute configuration of the minor isomer was not determined.
-
-
-
-
21
-
-
61349130553
-
-
2 resulted in the decreased yield of 7 28
-
2 resulted in the decreased yield of 7 (28%).
-
-
-
-
22
-
-
0003034713
-
-
It is reported that the ozonolysis of the vinylsilane does not give the corresponding aldehyde; see: (a) Büchi, G, Wüest, H. J. Am. Chem. Soc. 1978, 100, 294-295
-
It is reported that the ozonolysis of the vinylsilane does not give the corresponding aldehyde; see: (a) Büchi, G.; Wüest, H. J. Am. Chem. Soc. 1978, 100, 294-295.
-
-
-
-
23
-
-
33748937863
-
-
(b) Murakami, M.; Sakita, K.; Igawa, K.; Tomooka, K. Org. Lett. 2006, 8, 4023-4046.
-
(2006)
Org. Lett
, vol.8
, pp. 4023-4046
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-
Murakami, M.1
Sakita, K.2
Igawa, K.3
Tomooka, K.4
-
24
-
-
61349128320
-
-
The spirolactone 13 was obtained as a single diastereomer. The relative stereochemistry of 13 was not determined.
-
The spirolactone 13 was obtained as a single diastereomer. The relative stereochemistry of 13 was not determined.
-
-
-
-
25
-
-
61349183629
-
-
Lower amounts of methylamine (2 equiv) resulted in the decreased yield of 12 (<20%).
-
Lower amounts of methylamine (2 equiv) resulted in the decreased yield of 12 (<20%).
-
-
-
-
26
-
-
0037131653
-
-
Electrophilic 4,6-dibromination of 3-substituted phenol: (a) Osuna, M. R.; Agurrie, G.; Somanathan, R.; Molins, E. Tetrahedron: Asymmetry 2002, 13, 2261-2266.
-
Electrophilic 4,6-dibromination of 3-substituted phenol: (a) Osuna, M. R.; Agurrie, G.; Somanathan, R.; Molins, E. Tetrahedron: Asymmetry 2002, 13, 2261-2266.
-
-
-
-
27
-
-
0036339471
-
-
(b) Hashimoto, A.; Jacobson, A. E.; Rothman, R. B.; Dersch, C. M.; George, C.; F-Anderson, J. L.; Rice, K.C. Bioorg. Med. Chem. 2002, 10, 3319-3329.
-
(2002)
Bioorg. Med. Chem
, vol.10
, pp. 3319-3329
-
-
Hashimoto, A.1
Jacobson, A.E.2
Rothman, R.B.3
Dersch, C.M.4
George, C.5
F-Anderson, J.L.6
Rice, K.C.7
-
28
-
-
61349089686
-
-
Negoro, T.; Wada, M.; Someya, M. Bull. Fac. Educ. Wakayama Univ. Natur. Sci. 1998, 48, 1-7.
-
(1998)
Bull. Fac. Educ. Wakayama Univ. Natur. Sci
, vol.48
, pp. 1-7
-
-
Negoro, T.1
Wada, M.2
Someya, M.3
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29
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61349177755
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1
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1
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