Synthesis, characterization and biological activity of ring-substituted 6-benzylamino-9-tetrahydropyran-2-yl and 9-tetrahydrofuran-2-ylpurine derivatives

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 5, 2009, Pages 1938-1947

  Szüčová, Lucie ^a   Spíchal, Lukáš ^a   Doležal, Karel ^a   Zatloukal, Marek ^a   Greplová, Jarmila ^a   Galuszka, Petr ^a   Kryštof, Vladimír ^a   Voller, Jiří ^a   Popa, Igor ^a   Massino, Frank J ^b   Jørgensen, Jan Elo ^b   Strnad, Miroslav ^a  

^a PALACKÝ UNIVERSITY   (Czech Republic)

^b Senetek PLC   (United States)

Author keywords

Antisenescence; Cytokinins; Receptor; Stability

Indexed keywords

3 TOPOLIN; 6 (3 HYDROXYBENZYLAMINO) 9 TETRAHYDROFURAN 2 YLPURINE; 6 (3 HYDROXYBENZYLAMINO) 9 TETRAHYDROPYRAN 2 YLPURINE; 6 BENZYLAMINO 9 TETRAHYDROPYRAN 2 YL DERIVATIVE; 9 TETRAHYDROFURAN 2 YLPURINE DERIVATIVE; CYTOKININ; CYTOKININ DEHYDROGENASE; CYTOKININ OXIDASE; CYTOKININ RECEPTOR AHK3; CYTOKININ RECEPTOR CRE1; OXIDOREDUCTASE; PURINE DERIVATIVE; TETRAHYDROPYRAN DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG CYTOTOXICITY; DRUG DEGRADATION; DRUG STRUCTURE; DRUG SYNTHESIS; FIBROBLAST; HUMAN; HUMAN CELL; NONHUMAN; REACTION ANALYSIS; RECEPTOR AFFINITY; STRUCTURE ANALYSIS;

CELL LINE, TUMOR; CYTOKININS; DRUG STABILITY; FIBROBLASTS; FURANS; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; PURINES; PYRANS;

AMARANTHUS; BACTERIA (MICROORGANISMS); NICOTIANA TABACUM; TRITICUM AESTIVUM;

EID: 61349187806     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.01.041     Document Type: Article

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