Extrudable core system: Development of a single-layer osmotic controlled-release tablet

Journal of Controlled Release

Volumn 134, Issue 3, 2009, Pages 201-206

  Waterman, Kenneth C ^a   MacDonald, Bruce C ^a   Roy, Michael C ^a  

^a PFIZER INC   (United States)

Author keywords

Extrudable core technology; High dose drug delivery; Monolithic osmotic tablet; Oral controlled release; Osmotic tablet

Indexed keywords

EXTRUDABLE CORE TECHNOLOGY; HIGH DOSE DRUG DELIVERY; MONOLITHIC OSMOTIC TABLET; ORAL CONTROLLED-RELEASE; OSMOTIC TABLET;

OSMOSIS; SUGAR (SUCROSE); SUGARS;

CONTROLLED DRUG DELIVERY;

[2 (3,4 DICHLOROPHENOXY) 5 FLUORBENZYL]METHYLAMINE; ANTIDEPRESSANT AGENT; CARBOMER; CARBOPOL 974P; CARBOXYMETHYLCELLULOSE; CELLULOSE ACETATE; CP 607366; DODECYL SULFATE SODIUM; HYDROXYETHYLCELLULOSE; HYDROXYPROPYLCELLULOSE; HYDROXYPROPYLMETHYLCELLULOSE; MACROGOL 3350; MAGNESIUM STEARATE; METHYLAMMONIUM; SERTRALINE; SILDENAFIL; SORBITOL; SUGAR; TARTARIC ACID; UNCLASSIFIED DRUG; XANTHAN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG SOLUBILITY; NONHUMAN; OSMOSIS; OSMOTIC PRESSURE; PRIORITY JOURNAL; TABLET FORMULATION; VISCOSITY;

ADMINISTRATION, ORAL; CELLULOSE; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; DRUG COMPOUNDING; HYDROGEN-ION CONCENTRATION; OSMOSIS; POLYMERS; SOLUBILITY; TABLETS; VISCOSITY;

EID: 61349164186     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2008.11.017     Document Type: Article

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