Passive immunization with llama single-domain antibody fragments reduces foot-and-mouth disease transmission between pigs

Vaccine

Volumn 27, Issue 13, 2009, Pages 1904-1911

  Harmsen, M M ^a   Fijten, H P D ^a   Engel, B ^a   Dekker, A ^a   Eble P L ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Foot and mouth disease; Passive immunization; Single domain antibody

Indexed keywords

RECOMBINANT ANTIBODY; RECOMBINANT LLAMA SINGLE DOMAIN ANTIBODY FRAGMENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FOOT AND MOUTH DISEASE; FOOT AND MOUTH DISEASE VIRUS; GENE FUSION; IMMUNOPROPHYLAXIS; NONHUMAN; PASSIVE IMMUNIZATION; PRIORITY JOURNAL; SWINE; VIREMIA; VIRUS SHEDDING; VIRUS TRANSMISSION;

ANIMALS; ANTIBODIES, BISPECIFIC; ANTIBODIES, VIRAL; CAMELIDS, NEW WORLD; FOOT-AND-MOUTH DISEASE; FOOT-AND-MOUTH DISEASE VIRUS; IMMUNIZATION, PASSIVE; IMMUNOGLOBULIN FRAGMENTS; PLASMIDS; SWINE; SWINE DISEASES; VIRAL VACCINES; VIREMIA; VIRUS SHEDDING;

EID: 61349157275     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2009.01.110     Document Type: Article

References (29)

1. Fry E.E., Stuart D.I., and Rowlands D.J. The structure of foot-and-mouth disease virus. Curr Top Microbiol Immunol 288 (2005) 71-101
2. Knowles N.J., and Samuel A.R. Molecular epidemiology of foot-and-mouth disease virus. Virus Res 91 1 (2003) 65-80
3. Thompson D., Muriel P., Russell D., Osborne P., Bromley A., Rowland M., et al. Economic costs of the foot and mouth disease outbreak in the United Kingdom in 2001. Rev Sci Tech 21 3 (2002) 675-687
4. Salt J.S., Barnett P.V., Dani P., and Williams L. Emergency vaccination of pigs against foot-and-mouth disease: protection against disease and reduction in contact transmission. Vaccine 16 7 (1998) 746-754
5. Eblé P.L., Bouma A., De Bruin M.G.M., van Hemert-Kluitenberg F., van Oirschot J.T., and Dekker A. Vaccination of pigs two weeks before infection significantly reduces transmission of foot-and-mouth disease virus. Vaccine 22 11-12 (2004) 1372-1378
6. Eblé P.L., de Koeijer A.A., de Jong M.C., Engel B., and Dekker A. A meta-analysis quantifying transmission parameters of FMDV strain O Taiwan among non-vaccinated and vaccinated pigs. Prev Vet Med 83 (2008) 98-106
7. Goris N., Vandenbussche F., and De Clercq K. Potential of antiviral therapy and prophylaxis for controlling RNA viral infections of livestock. Antiviral Res 78 1 (2008) 170-178
8. Blancou J. History of the control of foot and mouth disease. Comp Immunol Microbiol Infect Dis 25 5-6 (2002) 283-296
9. Davidson FL. Alternative strategies for foot-and-mouth disease control in pigs: a thesis submitted in partial ffulfilment of the requirements of the University of Hertfordshire for the degree of Doctor of Philosophy. PhD thesis. Pirbright, United Kingdom: Pirbright Laboratory. 1997.
10. Harmsen M.M., and De Haard H.J. Properties, production, and applications of camelid single-domain antibody fragments. Appl Microbiol Biotechnol 77 1 (2007) 13-22
11. Harmsen M.M., Van Solt C.B., Fijten H.P.D., Van Keulen L., Rosalia R.A., Weerdmeester K., et al. Passive immunization of guinea-pigs with llama single-domain antibody fragments against foot-and-mouth disease. Vet Microbiol 120 3-4 (2007) 193-206
12. Harmsen M.M., Van Solt C.B., Fijten H.P.D., and Van Setten M.C. Prolonged in vivo residence times of llama single-domain antibody fragments in pigs by binding to porcine immunoglobulins. Vaccine 23 41 (2005) 4926-4934
13. Harmsen M.M., Fijten H.P.D., Dekker A., and Eblé P.L. Passive immunization of pigs with bispecific llama single-domain antibody fragments against foot-and-mouth disease and porcine immunoglobulin. Vet Microbiol 132 (2008) 56-64
14. Van der Linden R., De Geus B., Stok W., Bos W., Van Wassenaar D., Verrips T., et al. Induction of immune responses and molecular cloning of the heavy chain antibody repertoire of Lama glama. J Immunol Methods 240 1-2 (2000) 185-195
15. Harmsen M.M., van Solt C.B., Hoogendoorn A., van Zijderveld F.G., Niewold T.A., and van der Meulen J. Escherichia coli F4 fimbriae specific llama single-domain antibody fragments effectively inhibit bacterial adhesion in vitro but poorly protect against diarrhoea. Vet Microbiol 111 1-2 (2005) 89-98
16. Van de Laar T., Visser C., Holster M., Lopez C.G., Kreuning D., Sierkstra L., et al. Increased heterologous protein production by Saccharomyces cerevisiae growing on ethanol as sole carbon source. Biotechnol Bioeng 96 3 (2007) 483-494
17. Moonen P., Boonstra J., van der Honing R.H., Leendertse C.B., Jacobs L., and Dekker A. Validation of a LightCycler-based reverse transcription polymerase chain reaction for the detection of foot-and-mouth disease virus. J Virol Methods 113 1 (2003) 35-41
18. Conrath K.E., Lauwereys M., Wyns L., and Muyldermans S. Camel single-domain antibodies as modular building units in bispecific and bivalent antibody constructs. J Biol Chem 276 10 (2001) 7346-7350
19. Coppieters K., Dreier T., Silence K., de Haard H., Lauwereys M., Casteels P., et al. Formatted anti-tumor necrosis factor alpha VHH proteins derived from camelids show superior potency and targeting to inflamed joints in a murine model of collagen-induced arthritis. Arthritis Rheum 54 6 (2006) 1856-1866
20. Hmila I., Abdallah R.B., Saerens D., Benlasfar Z., Conrath K., Ayeb M.E., et al. VHH, bivalent domains and chimeric Heavy chain-only antibodies with high neutralizing efficacy for scorpion toxin AahI'. Mol Immunol 45 14 (2008) 3847-3856
21. Mateu M.G., and Verdaguer N. Functional and structural aspects of the interaction of foot-and-mouth disease virus with antibodies. In: Sobrino F., and Domingo E. (Eds). Foot and mouth disease current perspectives (2004), Horizon Bioscience, Norfolk 222-260
22. Aggarwal N., and Barnett P.V. Antigenic sites of foot-and-mouth disease virus (FMDV): an analysis of the specificities of anti-FMDV antibodies after vaccination of naturally susceptible host species. J Gen Virol 83 4 (2002) 775-782
23. Rieder E., Baxt B., Lubroth J., and Mason P.W. Vaccines prepared from chimeras of foot-and-mouth disease virus (FMDV) induce neutralizing antibodies and protective immunity to multiple serotypes of FMDV. J Virol 68 11 (1994) 7092-7098
24. De Groot A.S., and Scott D.W. Immunogenicity of protein therapeutics. Trends Immunol 28 11 (2007) 482-490
25. Chen W., Liu M., Jiao Y., Yan W., Wei X., Chen J., et al. Adenovirus-mediated RNA interference against foot-and-mouth disease virus infection both in vitro and in vivo. J Virol 80 7 (2006) 3559-3566
26. Chinsangaram J., Moraes M.P., Koster M., and Grubman M.J. Novel viral disease control strategy: adenovirus expressing alpha interferon rapidly protects swine from foot-and-mouth disease. J Virol 77 2 (2003) 1621-1625
27. Wu Q., Brum M.C., Caron L., Koster M., and Grubman M.J. Adenovirus-mediated type I interferon expression delays and reduces disease signs in cattle challenged with foot-and-mouth disease virus. J Interferon Cytokine Res 23 7 (2003) 359-368
28. Yang B., Lan X., Li X., Yin X., Li B., Han X., et al. A novel bi-functional DNA vaccine expressing VP1 protein and producing antisense RNA targeted to 5′UTR of foot-and-mouth disease virus can induce both rapid inhibitory effect and specific immune response in mice. Vaccine 26 (2008) 5477-5483
29. Goris N., De Palma A., Toussaint J.F., Musch I., Neyts J., and De Clercq K. 2'-C-Methylcytidine as a potent and selective inhibitor of the replication of foot-and-mouth disease virus. Antiviral Res 73 3 (2007) 161-168