Effect of genetic polymorphisms in UDP-glucuronosyltransferase 1A6 (UGT1A6) on acetylsalicylic acid metabolism in healthy female volunteers

Pharmacology

Volumn 83, Issue 4, 2009, Pages 237-242

  Van Oijen, Martijn G H ^a   Barthélémy, Christine ^b   Janssen, Marcel J R ^a   Joiris, Etienne ^b   Peters, Wilbert H M ^a   Laheij, Robert J F ^a   Smits, Paul ^a   Odou, Pascal ^b   Jansen, Jan B M J ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIV LILLE   (France)

Author keywords

Acetylsalicylic acid; Metabolites of aspirin; Pharmacogenetics; Pharmacokinetics; Salicylic acid; UDP glucuronosyltransferase 1A6; UGT1A6

Indexed keywords

ACETYLSALICYLIC ACID; DRUG METABOLITE; GLUCURONOSYLTRANSFERASE 1A6; SALICYLIC ACID; SALICYLURIC ACID;

ADULT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; DRUG BLOOD LEVEL; DRUG METABOLISM; FEMALE; GENE; GENETIC POLYMORPHISM; GENOTYPE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HOMOZYGOTE; HUMAN; NORMAL HUMAN; PRIORITY JOURNAL; UGT1A6 GENE; VALIDATION PROCESS;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; FEMALE; GLUCURONOSYLTRANSFERASE; HIPPURATES; HOMOZYGOTE; HUMANS; POLYMORPHISM, GENETIC; SALICYLIC ACID; YOUNG ADULT;

EID: 61349151705     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000205824     Document Type: Article

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