Optimizing trial design. Sequential, adaptive, and enrichment strategies

Circulation

Volumn 119, Issue 4, 2009, Pages 597-605

  Mehta, Cyrus ^a,b   Gao, Ping ^c   Bhatt, Deepak L ^d   Harrington, Robert A ^e   Skerjanec, Simona ^c   Ware, James H ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b Cytel Statistical Software and Services   (United States)

^c MEDICINES COMPANY   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e DUKE CLINICAL RESEARCH INSTITUTE   (United States)

Author keywords

Angioplasty; Clinical trials; Design; Methods; Statistics

Indexed keywords

PLACEBO;

ARTICLE; DISEASE SEVERITY; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HUMAN; MATHEMATICAL MODEL; MEDICAL RESEARCH; MORTALITY; PERCUTANEOUS CORONARY INTERVENTION; PRIORITY JOURNAL; REVASCULARIZATION; RISK REDUCTION;

ACUTE CORONARY SYNDROME; ANGIOPLASTY, TRANSLUMINAL, PERCUTANEOUS CORONARY; CLINICAL TRIALS AS TOPIC; HUMANS; MODELS, STATISTICAL;

EID: 61349150491     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.108.809707     Document Type: Article

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