Insulin resistance and therapy: Cross-talk between phosphatidylinositol-3 kinase and mitogen-activated protein kinase pathways

Medical Hypotheses

Volumn 72, Issue 5, 2009, Pages 610-

  Polyzos, Stergios A ^a   Kountouras, Jannis ^a   Zavos, Christos ^a  

^a Medical School   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; APELIN; GLUCOSE; HEMOGLOBIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; INTERLEUKIN 6 ANTIBODY; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RAS PROTEIN; SALICYLIC ACID; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

ADENOVIRUS; ATHEROMATOSIS; CELL GROWTH; ENZYME ACTIVITY; GLUCOSE METABOLISM; HYPERGLYCEMIA; HYPERLIPIDEMIA; INFLAMMATION; INSULIN RESISTANCE; INSULIN TREATMENT; LETTER; METABOLIC PARAMETERS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; THROMBOSIS;

1-PHOSPHATIDYLINOSITOL 3-KINASE; HUMANS; INSULIN RESISTANCE; MAP KINASE SIGNALING SYSTEM;

EID: 61349147709     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2008.12.019     Document Type: Letter

References (4)

1. Zhao L., Sun D., Cao F., Yin T., and Wang H. Can insulin resistance be reversed by insulin therapy?. Med Hypotheses 72 (2009) 34-35
2. In: DeGroot L.J., and Jameson J.L. (Eds). Endocrinology. 5th ed. (2006), Saunders/Elsevier, Philadelphia 975-1000
3. Polyzos SA, Kountouras J, Zavos C. Nonalcoholic fatty liver disease: the pathogenetic roles of insulin resistance and adipocytokines. Curr Mol Med 2009;9 [in press].
4. Gerstein H.C., Miller M.E., Byington R.P., et al. Effects of intensive glucose lowering in type 2 diabetes. N Engl J Med 358 (2008) 2545-2559