Synthesis and bioevaluation of ω-N-amino analogs of B13

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 5, 2009, Pages 1840-1848

  Bai, Aiping ^a   Szulc, Zdzislaw M ^a   Bielawski, Jacek ^a   Mayroo, Nalini ^a   Liu, Xiang ^a   Norris, James ^a   Hannun, Yusuf A ^a   Bielawska, Alicja ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Acid ceramidase; B13; Ceramide; Inhibitors; LCL204; LCL464; Lysosomes

Indexed keywords

2 N (12' N,N DIMETHYLAMINODODECANOYLAMINO) 1 (4''NITROPHENYL) 1,3 PROPANEDIOL; 2 N (TETRADECANOYLAMINO) 1 (4' NITROPHENYL) 1,3 PROPANEDIOL; 2 N (TETRADECYLAMINO) 1 (4' NITROPHENYL) 1,3 PROPANEDIOL; ACYLSPHINGOSINE DEACYLASE; B 13; CERAMIDE; LCL 204; LCL 464; OMEGA AMINO ACID; SPHINGOSINE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; PROTEIN DEGRADATION;

ACID CERAMIDASE; AMIDES; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; ENZYME INHIBITORS; HUMANS; INHIBITORY CONCENTRATION 50; PROPANOLAMINES;

EID: 61349110856     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.01.057     Document Type: Article

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