Confidence intervals on fit parameters derived from optical reflectance spectroscopy measurements

Journal of Biomedical Optics

Volumn 13, Issue 5, 2008, Pages

  Amelink, Arjen ^a   Robinson, Dominic J ^a   Sterenborg, Henricus J C M ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

confidence intervals; fitting; optical spectroscopy; statistical error; systematic error

Indexed keywords

CONFIDENCE INTERVAL; DIAGONAL ELEMENTS; FIT PARAMETERS; FITTING; FITTING MODEL; FREE PARAMETERS; NUMBER OF DEGREES OF FREEDOM; OPTICAL REFLECTANCE; OPTICAL SPECTROSCOPY; SECOND DERIVATIVES; SIMPLE METHOD; SQUARE ROOTS; STATISTICAL ERROR; SYNTHETIC DATASETS;

COVARIANCE MATRIX; REFLECTION; SPECTROSCOPY;

PARAMETER ESTIMATION;

ALGORITHM; ARTICLE; BIOLOGICAL MODEL; CHEMICAL MODEL; COMPUTER SIMULATION; CONFIDENCE INTERVAL; EVALUATION; METHODOLOGY; PHOTOMETRY; SPECTROSCOPY; STATISTICAL ANALYSIS; STATISTICAL MODEL;

ALGORITHMS; COMPUTER SIMULATION; CONFIDENCE INTERVALS; DATA INTERPRETATION, STATISTICAL; MODELS, BIOLOGICAL; MODELS, CHEMICAL; MODELS, STATISTICAL; PHOTOMETRY; SPECTRUM ANALYSIS;

EID: 60849126442     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.2982523     Document Type: Article

References (25)

1. O. R., Scepanovic, K. L., Bechtel, A. S., Haka, W. C., Shih, T. W., Koo, A. J., Berger, and M. S., Feld, " Determination of uncertainty in parameters extracted from single spectroscopic measurements, ", J. Biomed. Opt., 12, 064012 (2007). jbo JBOPFO 1083-3668 10.1117/1.2815692
2. T. J., Farrell, M. S., Patterson, and B. C., Wilson, " A diffusion theory model of spatially resolved, steady-state diffuse reflectance for the non-invasive determination of tissue optical properties, ", Med. Phys., 19, 879-888 (1992). mph MPHYA6 0094-2405 10.1118/1.596777
3. R. M. P., Doornbos, R., Lang, M. C., Aalders, F. W., Cross, and H. J. C. M., Sterenborg, " The determination of in vivo human tissue optical properties and absolute chromophore concentrations using spatially resolved steady-state diffuse reflectance spectroscopy, ", Phys. Med. Biol., 44, 967-981 (1999). pme PHMBA7 0031-9155 10.1088/0031-9155/44/4/012 (Pubitemid 29185386)
4. G., Zonios, L. T., Perelman, V., Backman, R., Manoharan, M., Fitzmaurice, J., Van-Dam, and M. S., Feld, " Diffuse reflectance spectroscopy of human adenomatous colon polyps, in vivo, ", Appl. Opt., 38, 6628-6637 (1999). apo APOPAI 0003-6935 10.1364/AO.38.006628 (Pubitemid 129567570)
5. N., Ghosh, S. K., Mohanty, S. K., Majumder, and P. K., Gupta, " Measurement of optical transport properties of normal and malignant human breast tissue, ", Appl. Opt., 40, 176-184 (2001). apo APOPAI 0003-6935 10.1364/AO.40.000176
6. J. C., Finlay and T. H., Foster, " Hemoglobin oxygen saturations in phantoms and, in vivo, from measurements of steady-state diffuse reflectance at a single, short source-detector separation, ", Med. Phys., 31, 1949-1959 (2004). mph MPHYA6 0094-2405 10.1118/1.1760188 (Pubitemid 38924813)
7. P., Thueler, I., Charvet, F., Bevilacqua, M. St., Ghislain, G., Ory, P., Marquet, P., Meda, B., Vermeulen, and C., Depeursinge, " In vivo, endoscopic tissue diagnostics based on spectroscopic absorption, scattering, and phase function properties, ", J. Biomed. Opt., 8 (4), 495-503 (2003). jbo JBOPFO 1083-3668 10.1117/1.1578494
8. G. M., Palmer and N., Ramanujam, " Monte Carlo-based inverse model for calculating tissue optical properties. Part I: theory and validation on synthetic phantoms, ", Appl. Opt., 45, 1062-1071 (2006). apo APOPAI 0003-6935 10.1364/AO.45.001062
9. T. J., Pfefer, L. S., Matchette, C. L., Bennett, J. A., Gall, J. N., Wilke, A. J., Durkin, and M. N., Ediger, " Reflectance-based determination of optical properties in highly attenuating tissue, ", J. Biomed. Opt., 8 (2), 206-215 (2003). jbo JBOPFO 1083-3668 10.1117/1.1559487
10. R., Reif, O., A'Amar, and I. J., Bigio, " Analytical model of light reflectance for extraction of the optical properties in small volumes of turbid media, ", Appl. Opt., 46, 7317-7328 (2007). apo APOPAI 0003-6935 10.1364/AO.46.007317
11. A., Amelink, M. P., Bard, S. A., Burgers, and H. J., Sterenborg, " In vivo, measurement of the local optical properties of tissue by use of differential path-length spectroscopy, ", Opt. Lett., 29, 1087-1089 (2004). opl OPLEDP 0146-9592 10.1364/OL.29.001087
12. M. P., Bard, A., Amelink, V., Noordhoek Hegt, W. J., Graveland, H. J., Sterenborg, H. C., Hoogsteden, and J. G., Aerts, " Measurement of hypoxia-related parameters in bronchial mucosa by use of optical spectroscopy, ", Am. J. Respir. Crit. Care Med., 171, 1178-1184 (2005). 7yf ZZZZZZ 1073-449X (Pubitemid 40663732)
13. R. L., van Veen, A., Amelink, M., Menke-Pluymers, C., van der Pol, and H. J., Sterenborg, " Optical biopsy of breast tissue using differential path-length spectroscopy, ", Phys. Med. Biol., 50, 2573-2581 (2005). pme PHMBA7 0031-9155 10.1088/0031-9155/50/11/009 (Pubitemid 40770640)
14. A., Amelink, O. P., Kaspers, H. J., Sterenborg, J. E., van der Wal, J. L., Roodenburg, and M. J., Witjes, " Non-invasive measurement of the morphology and physiology of oral mucosa by use of optical spectroscopy, ", Oral Oncol., 44, 65-71 (2008). 8el EJCCER 0964-1955 (Pubitemid 350251281)
15. A., Amelink and H. J. C. M., Sterenborg, " Measurement of the local optical properties of turbid media using differential pathlength spectroscopy, ", Appl. Opt., 43, 3048-3054 (2004). apo APOPAI 0003-6935 10.1364/AO.43.003048
16. O. P., Kaspers, H. J. C. M., Sterenborg, and A., Amelink, " Controlling the optical path length in turbid media using differential path-length spectroscopy: fiber diameter dependence, ", Appl. Opt., 47, 365-371 (2008). apo APOPAI 0003-6935 10.1364/AO.47.000365 (Pubitemid 351462476)
17. S. W., van de Poll, " Raman spectroscopy of atherosclerosis, ", Ph.D., Thesis, Univ. of Leiden, p. 123, ISBN 90-9016109-0 (2003).
18. S., Prahl, see, http://omlc.ogi.edu/spectra/hemoglobin (1999).
19. F., James, Minuit - function minimization and error analysis, Reference Manual Version 94.1, Cern (1998).
20. P. R., Bevington and D. K., Robinson, Data Reduction and Error Analysis for the Physical Sciences, McGraw-Hill, New York (1969).
21. J. R., Mourant, T., Fuselier, J., Boyer, T. M., Johnson, and I. J., Bigio, " Prediction and measurements of scattering and absorption over broad wavelength ranges in tissue phantoms, ", Appl. Opt., 36, 949-957 (1997). apo APOPAI 0003-6935 10.1364/AO.36.000949 (Pubitemid 127638552)
22. G. M., Palmer, C., Zhu, T. M., Breslin, F., Xu, K. W., Gilchrist, and N., Ramanujam, " Monte Carlo-based inverse model for calculating tissue optical properties. Part II: Application to breast cancer diagnosis, ", Appl. Opt., 45, 1072-1078 (2006). apo APOPAI 0003-6935 10.1364/AO.45.001072
23. L. T., Perelman, V., Backman, M., Wallace, G., Zonios, R., Manoharan, A., Nusrat, S., Shields, M., Seiler, C., Lima, T., Hamano, I., Itzkan, J., Van Dam, J. M., Crawford, and M. S., Feld, " Observation of periodic fine structure in reflectance from biological tissue: a new technique for measuring nuclear size distribution, ", Phys. Rev. Lett., 80, 627-630 (1998). prl PRLTAO 0031-9007 10.1103/PhysRevLett.80.627 (Pubitemid 128622229)
24. M. B., Wallace, L. T., Perelman, V., Backman, J. M., Crawford, M., Fitzmaurice, M., Seiler, K., Badizadegan, S. J., Shields, I., Itzkan, R. R., Dasari, J., Van Dam, and M. S., Feld, " Endoscopic detection of dysplasia in patients with barrett's esophagus using light-scattering spectroscopy, ", Gastroenterology, 119, 677-682 (2000). gst GASTAB 0016-5085 10.1053/gast.2000.16511
25. V., Backman, R., Gurjar, K., Badizadegan, I., Itzkan, R. R., Dasari, L. T., Perelman, and M. S., Feld, " Polarized light scattering spectroscopy for quantitative measurement of epithelial cellular structures, in situ, ", IEEE J. Sel. Top. Quantum Electron., 5, 1019-1026 (1999). isq IJSQEN 1077-260X 10.1109/2944.796325 (Pubitemid 30544900)