Adenovirus-mediated wild-type p53 transfer radiosensitizes H1299 cells to subclinical-dose carbon-ion irradiation through the restoration of p53 function

Cancer Biotherapy and Radiopharmaceuticals

Volumn 24, Issue 1, 2009, Pages 57-65

  Liu, Bing ^a,b   Zhang, Hong ^a   Duan, Xin ^a   Hao, Jifang ^a   Xie, Yi ^a   Zhou, Qingming ^a   Wang, Yanling ^a   Tian, Yuan ^b   Wang, Tao ^b  

^a INSTITUTE OF MODERN PHYSICS   (China)

^b Lanzhou Command Center for Disease Prevention and Control   (China)

Author keywords

Adenovirus vector; Carbon ion beam; Non small cell lung cancer; p53 gene transfer; Radiosensitivity; Subclinical dose

Indexed keywords

ADENOVIRUS VECTOR; COBALT 60; MESSENGER RNA; PROTEIN MDM2; PROTEIN P21; PROTEIN P53;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER RADIOTHERAPY; CELL CYCLE; CELL SURVIVAL; COBALT TELETHERAPY; CONTROLLED STUDY; DNA DAMAGE; DNA FRAGMENTATION; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GAMMA IRRADIATION; GENE TRANSFER; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; ION THERAPY; LUNG CANCER; LUNG NON SMALL CELL CANCER; NICK END LABELING; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION DOSE; RADIOSENSITIZATION; TUMOR SUPPRESSOR GENE; WESTERN BLOTTING;

ADENOVIRIDAE; APOPTOSIS; CARBON; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; FLOW CYTOMETRY; GENES, P53; GENETIC VECTORS; HUMANS; IONS; LUNG NEOPLASMS; RADIATION-SENSITIZING AGENTS; TIME FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 60849125422     PISSN: 10849785     EISSN: None     Source Type: Journal    
DOI: 10.1089/cbr.2008.0514     Document Type: Article

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