Establishing the added benefit of measuring MMP9 in FOB positive patients as a part of the Wolverhampton colorectal cancer screening programme

BMC Cancer

Volumn 9, Issue , 2009, Pages

  Wilson, Sue ^a   Taskila, Taina ^a   Ismail, Tariq ^b   Stocken, Deborah D ^a   Martin, Ashley ^a   Redman, Val ^a   Wakelam, Michael ^a   Perry, Ian ^c   Hobbs, Richard ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b QUEEN ELIZABETH HOSPITAL   (United Kingdom)

^c NEW CROSS HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE B; TUMOR MARKER;

ADULT; AGED; ARTICLE; CANCER SCREENING; COLONOSCOPY; COLORECTAL CANCER; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; FALSE POSITIVE RESULT; HUMAN; MAJOR CLINICAL STUDY; OCCULT BLOOD TEST; PILOT STUDY; PREDICTION; PROTEIN BLOOD LEVEL; SENSITIVITY AND SPECIFICITY; BLOOD; CANCER DIAGNOSIS; COLORECTAL TUMOR; EVALUATION; MIDDLE AGED; OCCULT BLOOD; PREDICTION AND FORECASTING;

AGED; COLORECTAL NEOPLASMS; EARLY DETECTION OF CANCER; HUMANS; MATRIX METALLOPROTEINASE 9; MIDDLE AGED; OCCULT BLOOD; PILOT PROJECTS; PREDICTIVE VALUE OF TESTS; TUMOR MARKERS, BIOLOGICAL;

EID: 60849120129     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-9-36     Document Type: Article

References (14)

1. Cancer Statistics: Registration of cancer diagnosed in England MB1 No 31 Office of National Statistics 2000
2. Mortality statistics: Review of the Registrar General on deaths by cause, sex and age in England and Wales Series DH2 No 29 Office of National Statistics 2003
3. Macafee D Gemmil E Lund J Colorectal cancer: Current care, future innovations and economic considerations Expert Rev Pharmacoeconomics Outcomes Res 2006, 6:195-206. 10.1586/14737167.6.2.195
4. Coleman M Cooper N Ellis L Rachet B Rasulo D Shah A Westlake S One- and five-year relative survival for patients diagnosed in 1998-2004 in 'Spearhead' Primary Care Trusts (PCTs), compared with those in the rest of England: 10 common cancers, by sex National Statistics 2008
5. Hewitson P Glasziou P Watson E Towler B Irwig L Cochrane systematic review of colorectal cancer screening using the fecal occult blood test (hemoccult): An update Am J Gastroenterol 2008, 103(6):1541-1549. 10.1111/j.1572-0241.2008.01875.x 18479499
6. Atkin WS Impending or pending? The national bowel cancer screening programme Bmj 2006, 332:7544-742. 1420723 16554333 10.1136/ bmj.38797.494757.47
7. Results of the first round of a demonstration pilot of screening for colorectal cancer in the United Kingdom Bmj 2004, 329(7458):133. 478217 15237087 10.1136/bmj.38153.491887.7C
8. Weller D Coleman D Robertson R Butler P Melia J Campbell C Parker R Patnick J Moss S The UK colorectal cancer screening pilot: Results of the second round of screening in England Br J Cancer 2007, 97(12):1601-1605. 10.1038/sj.bjc.6604089 18026197
9. Gatto NM Frucht H Sundararajan V Jacobson JS Grann VR Neugut AI Risk of perforation after colonoscopy and sigmoidoscopy: A population-based study J Natl Cancer Inst 2003, 95(3):230-236. 12569145
10. Collins HM Morris TM Watson SA Spectrum of matrix metalloproteinase expression in primary and metastatic colon cancer: Relationship to the tissue inhibitors of metalloproteinases and membrane type-1-matrix metalloproteinase Br J Cancer 2001, 84(12):1664-1670. 10.1054/ bjoc.2001.1831 11401321
11. Hurst NG Stocken DD Wilson S Keh C Wakelam MJ Ismail T Elevated serum matrix metalloproteinase 9 (MMP-9) concentration predicts the presence of colorectal neoplasia in symptomatic patients Br J Cancer 2007, 97(7):971-977. 10.1038/sj.bjc.6603958 17912241
12. Heslin MJ Yan J Johnson MR Weiss H Diasio RB Urist MM Role of matrix metalloproteinases in colorectal carcinogenesis Ann Surg 2001, 233(6):786-792. 1421321 11371737 10.1097/00000658-200106000-00008
13. Parsons SL Watson SA Collins HM Griffin NR Clarke PA Steele RJ Gelatinase (MMP-2 and -9) expression in gastrointestinal malignancy Br J Cancer 1998, 78(11):1495-1502. 9836483
14. Goehring C Perrier A Morabia A Spectrum bias: A quantitative and graphical analysis of the variability of medical diagnostic test performance Stat Med 2004, 23(1):125-135. 10.1002/sim.1591 14695644