Analysis of biofluids for gamma-hydroxybutyrate (GHB) and gamma-butyrolactone (GBL) by headspace GC-FID and GC-MS
LeBeau MA, Montgomery MA, Miller ML, Burmeister SG. Analysis of biofluids for gamma-hydroxybutyrate (GHB) and gamma-butyrolactone (GBL) by headspace GC-FID and GC-MS. J Anal Toxicol 2000 24 (6 421 8.
Determination of gamma-hydroxybutyrate (GHB) in biological specimens by gas chromatography-mass spectrometry
Couper FJ, BK Logan. Determination of gamma-hydroxybutyrate (GHB) in biological specimens by gas chromatography-mass spectrometry. J Anal Toxicol 2000 24 (1 1 7.
US Food and Drug Administration. FDA talk paper: FDA approves Xyrem for cataplexy attacks in patients with narcolepsy. http://www.fda.gov/bbs/topics/ ANSWERS/2002/ANS01157.html.
Sodium oxybate demonstrates long-term efficacy for the treatment of cataplexy in patients with narcolepsy
US Xyrem® Multicenter Study Group.
US Xyrem® Multicenter Study Group. Sodium oxybate demonstrates long-term efficacy for the treatment of cataplexy in patients with narcolepsy. Sleep Med 2004 5 (2 119 23.
A 12-month, open-label, multicenter extension trial of orally administered sodium oxybate for the treatment of narcolepsy
US. Xyrem® Multicenter Study Group.
US. Xyrem® Multicenter Study Group. A 12-month, open-label, multicenter extension trial of orally administered sodium oxybate for the treatment of narcolepsy. Sleep 2003 26 (1 31 5.
Jazz Pharmaceuticals, Inc. Palo Alto, CA: Jazz Pharmaceuticals
Jazz Pharmaceuticals, Inc. Xyrem® (sodium oxybate) oral solution. Product monograph. Palo Alto, CA : Jazz Pharmaceuticals, 2005, http://jazzph.isat-tech.com/media/PI.pdf.
Correlation of blood levels of 4-hydroxybutyrate with state of consciousness
Helrich M, McAslan TC, Skolnick S, Bessman SP. Correlation of blood levels of 4-hydroxybutyrate with state of consciousness. Anesthesiology 1964 25 : 771 5.