Evans syndrome: A study of six cases with review of literature

Hematology

Volumn 13, Issue 6, 2008, Pages 356-360

  Dhingra, Kajal Kiran ^a   Jain, Deepali ^a   Mandal, Shramana ^a   Khurana, Nita ^a   Singh, Tejinder ^a   Gupta, Naresh ^a  

^a LOK NAYAK HOSPITAL   (India)

Author keywords

Anemia; Autoimmune; Evans; Haemolytic; Thrombocytopenia

Indexed keywords

BILIRUBIN; COMPLEMENT COMPONENT C3D; HAPTOGLOBIN; IMMUNOGLOBULIN; IMMUNOGLOBULIN G ANTIBODY; LACTATE DEHYDROGENASE; STEROID;

ADOLESCENT; ADULT; AUTOIMMUNE HEMOLYTIC ANEMIA; BLEEDING DISORDER; BONE MARROW BIOPSY; CHILD; CLINICAL ARTICLE; COOMBS TEST; CYTOPENIA; ERYTHROCYTE; ERYTHROID HYPERPLASIA; FEMALE; HUMAN; HYPERPLASIA; IDIOPATHIC THROMBOCYTOPENIC PURPURA; JAUNDICE; MALE; MEGAKARYOCYTE; MEGAKARYOCYTIC HYPERPLASIA; PALLOR; PRIORITY JOURNAL; REMISSION; RETICULOCYTE COUNT; RETICULOCYTOSIS; REVIEW; THROMBOCYTE COUNT; CASE REPORT; PATHOLOGY; SYNDROME;

ANEMIA, HEMOLYTIC, AUTOIMMUNE; COOMBS' TEST; HUMANS; PURPURA, THROMBOCYTOPENIC, IDIOPATHIC; SYNDROME;

EID: 60849098456     PISSN: 10245332     EISSN: 16078454     Source Type: Journal    
DOI: 10.1179/102453308X343518     Document Type: Review

References (21)

1. Evans RS, Takahash K, Duane RT, Payne R, Liu C. Primary thrombocytopenic purpura and acquired haemolytic anemia: Evidence for a common etiology. AMA Arch Intern Med 1951; 87: 48-65.
2. Pirofsky B. Clinical aspects of autoimmune hemolytic anemia. Semin Hematol 1976; 13: 251-265.
3. Dash S, Marwaha R, Trehan A. Attenuated form of Evans syndrome among paediatric ITP patients. Indian Pediatr 2006; 43: 340-343.
4. McLeod AG, Pai M, Carter RF, Squire J, Barr RD. Familial Evans syndrome: a report of an affected sibship. J Pediatr Hematol Oncol 1999; 21: 244-247.
5. Wang WC. Evans syndrome in childhood: Pathophysiology, clinical course, and treatment. Am J Pediatr Hematol Oncol 1988; 10: 330-338.
6. Prasad M, Gang C, Winfred W. Evans syndrome: Results of a national survey. Am J Pediatr Hematol Oncol 1997; 19: 433-437.
7. Pui CH, Wilimas J, Wang W. Evans syndrome in childhood. Eur J Haematol 2006; 76: 526-530.
8. Park CY, Chung CH. A Patient with mixed type Evans syndrome: Efficacy of rituximab treatment. Korean Med Sci 2006; 21: 1115-1116.
9. Savasan S, Warrier I, Ravindranath I. The spectrum of Evans' syndrome. Arch Dis Child 1997; 77: 245-248.
10. Martino R, Muniz-Diaz E, Arilla M. Combined autoimmune cytopenias. Haematologica 1995; 80: 305-310.
11. Miller BA, Schultz Beardsley D. Autoimmune pancytopenia of childhood associated with multisystem disease manifestations. J Pediatr 1983; 103: 877-878.
12. Zuelzer WW, Mastrangelo R, Stulberg CS, Poulik MD, Pageb RH, Thompson RI. Autoimmune hemolytic anemia. Natural history and viral-immunologic interactions in childhood. Am J Med 1970; 49: 80-93.
13. Avcin T, Jazbec J, Kuhar M, Zupancic M, Rozman B. Evans syndrome associated with antiphospholipid antibodies. J Pediatr Hematol Oncol 2003; 25: 755-756.
14. Keung YK, Mallarino MC, Cobos E. Drug-induced evans syndrome. Ann Intern Med 1998; 128: 327
15. Kakaiya RM, Sherman LA, Miller WV, Katz AJ. Nature of platelet antibody in Evans syndrome: A case report. Ann Clin Lab Sci 1981; 11: 511-515.
16. Teachey DT, Manno CS, Axsom KM et al. Unmasking Evans syndrome: T-cell phenotype and apoptotic response reveal autoimmune lymphoproliferative syndrome (ALPS). Blood 2005; 105: 2443-2448.
17. Scaradavou A, Bussel J. Evans syndrome. Results of a pilot study utilizing a multiagent treatment protocol. J Pediatr Hematol Oncol 1995; 17: 290-295.
18. Raetz E, Zecca M, Nobili B et al. Rituximab for the treatment of refractory autoimmune hemolytic anemia in children. Blood 2003; 101: 3857-3861.
19. Beatty PG, Adams RH. Treatment of severe Evans syndrome with an allogenic cord blood transplant. Bone Marrow Transplant 1997; 20: 427-429.
20. Silverstein MN, Heck FJ. Acquired hemolytic anemia and associated thrombocytopenic purpura: With special reference to Evans' syndrome. Mayo Clin Proc 1962; 37: 122-128.
21. Ng SC. Evans syndrome: A report on 12 patients. Clin Lab Hematol 1992; 14: 189-193.