Yolk sac on transvaginal ultrasound as a prognostic indicator in the treatment of ectopic pregnancy with single-dose methotrexate

American Journal of Obstetrics and Gynecology

Volumn 200, Issue 3, 2009, Pages 338.e1-338.e4

  Lipscomb, Gary H ^a   Gomez, Isabel G ^a   Givens, Vanessa M ^a   Meyer, Norman L ^a   Bran, Derita F ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

ectopic pregnancy; methotrexate; predictors of failure

Indexed keywords

CHORIONIC GONADOTROPIN; FOLINIC ACID; METHOTREXATE; PROGESTERONE;

ADULT; AGE DISTRIBUTION; ANAMNESIS; ARTICLE; BODY SURFACE; CONTROLLED STUDY; DRUG TREATMENT FAILURE; FEMALE; FETUS; HEART CONTRACTION; HORMONE BLOOD LEVEL; HUMAN; HUMAN TISSUE; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MEDICAL RECORD REVIEW; PARITY; PREGNANCY; PRIORITY JOURNAL; PROGESTERONE BLOOD LEVEL; PROGNOSIS; REPEATED DRUG DOSE; RETROSPECTIVE STUDY; SINGLE DRUG DOSE; TRANSVAGINAL ECHOGRAPHY; UTERINE CERVIX; UTERINE TUBE PREGNANCY; YOLK SAC;

EID: 60849094465     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajog.2008.12.006     Document Type: Article

References (13)

1. Kooi S., and Kock H.C. A review of the literature on nonsurgical treatment in tubal pregnancies. Obstet Gynecol Surv 47 (1992) 739-749
2. Glock J.L., Johnson J.V., and Brumsted J.R. Efficacy and safety of single-dose systemic methotrexate in the treatment of ectopic pregnancy. Fertil Steril 62 (1994) 716-721
3. Ransom M.X., Garcia A.J., Bohrer M., Corsan G.H., and Kemmann E. Serum progesterone as a predictor of methotrexate success in the treatment of ectopic pregnancy. Obstet Gynecol 83 (1994) 1033-1037
4. Corsan G.H., Karacan M., Qasim S., Bohrer M.K., Ransom M.X., and Kemmann E. Identification of hormonal parameters for successful systemic single-dose methotrexate therapy in ectopic pregnancy. Hum Reprod 10 (1995) 2719-2722
5. Shalev E., Peleg D., Bustan M., Romano S., and Tsabari A. Limited role for intratubal methotrexate treatment of ectopic pregnancy. Fertil Steril 63 (1995) 20-24
6. Stika C.S., Anderson L., and Frederiksen M.C. Single-dose methotrexate for the treatment of ectopic pregnancy: Northwestern Memorial Hospital three-year experience. Am J Obstet Gynecol 174 (1996) 1840-1846
7. Lipscomb G.H., McCord M.L., Stovall T.G., Huff G., Portera S.G., and Ling F.W. Predictors of success of methotrexate treatment in women with tubal ectopic pregnancies. N Engl J Med 341 (1999) 1974-1978
8. Lipscomb G.H., Givens V.A., Meyer M.L., and Bran D. Previous ectopic pregnancy as a risk factor for failure of systemic methotrexate therapy. Fertil Steril 81 (2004) 1221-1224
9. Bixby S., Tello R., and Kuligowska E. Presence of a yolk sac on transvaginal sonography is the most reliable predictor of single-dose methotrexate treatment failure in ectopic pregnancy. J Ultrasound Med 24 (2005) 591-598
10. Potter M.B., Lepine L.A., and Jamieson D.J. Predictors of success with methotrexate treatment of tubal ectopic pregnancy at Grady Memorial Hospital. Am J Obstet Gynecology 188 (2003) 1192-1194
11. Stovall T.G., Ling F.W., Carson S.A., and Buster J.E. Nonsurgical diagnosis and treatment of tubal pregnancy. Fertil Steril 54 (1990) 537-538
12. Stovall T.G., Ling F.W., Gray L.A., Carson S.A., and Buster J.E. Methotrexate treatment of unruptured ectopic pregnancy: a report of 100 cases. Obstet Gynecol 77 (1991) 749-753
13. Stovall T.G., and Ling F.W. Single-dose methotrexate: an expanded clinical trial. Am J Obstet Gynecol 168 (1993) 1759-1762