Anti-inflammatory and analgesic components from "hierba santa," a traditional medicine in Peru

Journal of Natural Medicines

Volumn 63, Issue 2, 2009, Pages 147-158

  Kawano, Marii ^a   Otsuka, Mayumi ^b   Umeyama, Kazuhiro ^b   Yamazaki, Mikio ^b,c   Shiota, Tetsuo ^d   Satake, Motoyoshi ^e   Okuyama, Emi ^a  

^a JOSAI INTERNATIONAL UNIVERSITY   (Japan)

^b CHIBA UNIVERSITY   (Japan)

^c NIIGATA UNIVERSITY OF PHARMACY AND APPLIED LIFE SCIENCES   (Japan)

^d Institute de Agri Cultura Andina y Amazonia   (Peru)

^e UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Carboline; Analgesic; Anti inflammation; Cestrum; Hierba santa; Spirostanol

Indexed keywords

2 SEC BUTYL 4,6 DIHYDROXYPHENYL BETA DEXTRO GLUCOPYRANOSIDE; ACETIC ACID; ACETYLCHOLINE; AMINOPHENAZONE; ANALGESIC AGENT; ANTIINFLAMMATORY AGENT; BETA CARBOLINE; CESTRUMINE A; CESTRUSIDE A; CESTRUSIDE B; METHAMPHETAMINE; NICOTIFLORIN; NORADRENALIN; PINORESINOL; PROSTAGLANDIN E1; PROSTAGLANDIN E2; RUTOSIDE; SITOGLUSIDE; SPIROSTANOL; SUBSTANCE P; UNCLASSIFIED DRUG; URSOLIC ACID;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; AORTA; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CESTRUM; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG ISOLATION; FAST ATOM BOMBARDMENT MASS SPECTROMETRY; GUINEA PIG; HERB; HIERBA SANTA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ILEUM; INTESTINE CONTRACTION; MALE; MEDICINAL PLANT; MOUSE; NONHUMAN; PERU; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; WRITHING TEST;

ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS; CESTRUM; GUINEA PIGS; ILEUM; INFLAMMATION; MALE; MEDICINE, TRADITIONAL; MICE; MUSCLE CONTRACTION; PAIN; PAIN MEASUREMENT; PERU; PLANT EXTRACTS;

EID: 60849093461     PISSN: 13403443     EISSN: 18610293     Source Type: Journal    
DOI: 10.1007/s11418-008-0302-8     Document Type: Article

References (28)

1. V De Feo 1992 Medicinal and magical plants in the northern Peruvian Andes Fitoterapia 63 417 440
2. Duke AJ, Martinez VR (1994) Amazonian ethnobotanical dictionary. CRC, Boca Raton
3. RW Bussmann D Sharon 2006 Traditional medicinal plant use in Northern Peru: tracking two thousand years of healing culture J Ethnobiol Ethnomed 2 47
4. GB Hammond ID Fernandez LF Villegas AJ Vaisberg 1998 A survey of traditional medicinal plants from the Callejon de Huaylas, Department of Ancash, Peru J Ethnopharmacol 61 17 30
5. Soukup J (1980-1987) Vocabulario de los nombres vulgares de la flora eruana y catalogo de generos. SDB, Lima, Peru
6. Flores FA (1999) Inventario Taxonomico de la Flora de la Amazonia Peruana. Herbario Ethnobotánico Amazónico, Iquitos, Perú
7. Chavez NA (1977) La materia Medica en el Incanato. Velasquez Mejia Baca, Lima, Peru
8. F Faini R Torres F Delle Monache GB Marini-Bettolo M Castillo 1980 1-Acetyl-3-carboxy-beta-carboline, a new acid and other constituents of Vestia lycioides Planta Med 38 128 132
9. F Faini M Castillo R Torres 1978 A new beta-carboline alkaloid from Vestia lycioides Phytochemistry 17 338
10. I Razmilic M Castillo JT Lopez 1980 New synthesis of 1-acetyl-3- (methoxycarbonyl)-beta-carboline J Heterocycl Chem 17 595 596
11. M Haraguchi Y Mimaki M Motidome H Morita K Takeya H Itokawa A Yokosuka Y Sashida 2000 Steroidal saponins from the leaves of Cestrum sendtenerianum Phytochemistry 55 715 720
12. M Haraguchi M Motidome H Morita K Takeya H Itokawa Y Mimaki Y Sashida 1999 New polyhydroxylated steroidal sapogenin and saponin from the leaves of Cestrum sendtenerianum Chem Pharm Bull 47 582 584
13. T Deyama 1983 The constituents of Eucommia ulmoides Oliv. I. Isolation of (+)-medioresinol di-O-beta-d-glucopyranoside Chem Pharm Bull 31 2993 2997
14. GF Pauli P Junior 1995 Phenolic glycosides from Adonis aleppica Phytochemistry 38 1245 1250
15. Sahai M, Singh M, Singh AK, Hara N, Fujimoto Y (1994) Cesternosides A and B, novel glucosides from the leaves of Cestrum nocturnum. J Chem Res Synop 22-23
16. T Kosuge M Yokota K Sugiyama T Mure H Yamazawa T Yamamoto 1985 Studies on bioactive substances in crude drugs used for arthritic diseases in traditional Chinese medicine. III. Isolation and identification of anti-inflammatory and analgesic principles from the whole herb of Pyrola rotundifolia L Chem Pharm Bull 33 5355 5357
17. IM Villasnor J Angelada AP Canlas D Echegoyen 2002 Bioactivity studies on b-sitosterol and its glucoside Phytother Res 16 417 421
18. E Okuyama K Suzumura M Yamazaki 1995 Pharmacologically active components of Todopon Puok (Fagraea racemosa), a medicinal plant from Borneo Chem Pharm Bull 43 2200 2204
19. J Liu 1995 Pharmacology of oleanolic acid and ursolic acid J Ethnopharmacol 49 57 68
20. MC Recio RM Giner S Manez J Gueho HR Julien K Hostettmann JL Rios 1995 Investigations on the steroidal anti-inflammatory activity of triterpenoids from Diospyros leucomelas Planta Med 61 9 12
21. T Tsuruga YT Chun Y Ebizuka U Sankawa 1991 Biologically active constituents of Melaleuca leucadendron: inhibitors of induced histamine release from rat mast cells Chem Pharm Bull 39 3276 3278
22. T Ringbom L Segura Y Noreen P Perera L Bohlin 1998 Ursolic acid from Plantago major, a selective inhibitor of cyclooxygenase-2 catalyzed prostaglandin biosynthesis J Nat Prod 61 1212 1215
23. M-L Yang P-C Kuo AG Damu R-J Chang W-F Chiou T-S Wu 2006 A versatile route to the synthesis of 1-substituted beta-carbolines by a single step Pictet-Spengler cyclization Tetrahedron 62 10900 10906
24. H Inouye Y Takeda H Nishimura 1973 On the lignan glucosides of Symplocos lucida Yakugaku Zasshi 93 44 46
25. E Okuyama T Hasegawa T Matsushita H Fujimoto M Ishibashi M Yamazaki 2001 Analgesic components of Saposhnikovia root (Saposhnikovia divaricata) Chem Pharm Bull 49 154 160
26. E Okuyama K Umeyama M Yamazaki Y Kinoshita Y Yamamoto 1995 Usnic acid and diffractaic acid as analgesic and antipyretic components of Usnea diffracta Planta Med 61 113 115
27. T Nakamura E Okuyama M Yamazaki 1996 Neurotropic components from star anise (Illicium verum Hook. fil.) Chem Pharm Bull 44 1908 1914
28. SK Sadhu E Okuyama H Fujimoto M Ishibashi 2003 Separation of Leucas aspera, a medicinal plant of Bangladesh, guided by prostaglandin inhibitory and antioxidant activities Chem Pharm Bull 51 595 598