Probable hepatotoxicity related to Nerium oleander extract in a patient with metastatic synovial sarcoma of the knee

Journal of Alternative and Complementary Medicine

Volumn 15, Issue 2, 2009, Pages 113-

  Altan, Ege ^a   Bitik, Berivan ^a   Kalpakci, Yasin ^a   Dogan, Erkan ^a   Altundag, Kadri ^a  

^a HACETTEPE UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ANVIRZEL; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; DOXORUBICIN; ETOPOSIDE; GAMMA GLUTAMYLTRANSFERASE; IFOSFAMIDE; NERIUM OLEANDER EXTRACT; UNCLASSIFIED DRUG;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ASCITES; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; BLOATING; BONE METASTASIS; CANCER COMBINATION CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURGERY; CARDIOPULMONARY ARREST; CASE REPORT; DISSEMINATED INTRAVASCULAR CLOTTING; FEMALE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; HUMAN; KNEE; LETTER; LIVER TOXICITY; LUNG METASTASIS; MULTIPLE CYCLE TREATMENT; NAUSEA; PRIORITY JOURNAL; SIDE EFFECT; STOMACH PAIN; SYNOVIAL SARCOMA; VOMITING;

ADULT; ANTINEOPLASTIC AGENTS; DRUG-INDUCED LIVER INJURY; FATAL OUTCOME; FEMALE; HUMANS; INJECTIONS, INTRAMUSCULAR; KNEE JOINT; LUNG NEOPLASMS; NERIUM; PLANT EXTRACTS; SARCOMA, SYNOVIAL; SOFT TISSUE NEOPLASMS;

EID: 60749133598     PISSN: 10755535     EISSN: None     Source Type: Journal    
DOI: 10.1089/acm.2008.0459     Document Type: Letter

References (4)

1. Langford SD, Boor PJ. Oleander toxicity: An examination of human and animal toxic exposures. Toxicology 1996;109:1-13.
2. Cheeke PR. Natural Toxicants in Feeds, Forages, and Poisonous Plants, 2nd ed. Danville: IL: Interstate Publishers, 1998:479.
3. Mekhail T, Kaur H, Ganapathi R, et al. Phase 1 trial of Anvirzel in patients with refractory solid tumors. Invest New Drugs 2006;24:423-427.
4. Adam SE, Al-Yahya MA, Al-Farhan AH. Response of Najdi sheep to oral administration of Citrillus colocynthis fruits, Nerium oleander leaves or their mixture. Small Rumin Res 2001;40:239-244.