Should idiopathic short stature be treated with growth hormone?

Nature Clinical Practice Endocrinology and Metabolism

Volumn 5, Issue 3, 2009, Pages 148-149

  Savage, Martin O ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; RECOMBINANT GROWTH HORMONE; SOMATOMEDIN C;

BODY HEIGHT; CHILD; DOSE RESPONSE; DRUG MEGADOSE; HUMAN; IDIOPATHIC DISEASE; PRIORITY JOURNAL; PROGNOSIS; SHORT STATURE; SHORT SURVEY; SMALL FOR DATE INFANT; TREATMENT RESPONSE; TURNER SYNDROME;

GROWTH DISORDERS; GROWTH HORMONE; HUMANS;

EID: 60749131706     PISSN: 17458366     EISSN: 17458374     Source Type: Journal    
DOI: 10.1038/ncpendmet1074     Document Type: Short Survey

References (9)

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2. Ranke MB (1996) Towards a consensus on the definition of idiopathic short stature. Horm Res 45 (Suppl 2): 64-66
3. Savage MO et al. (2006) Endocrine assessment, molecular characterization and treatment of growth hormone insensitivity disorders. Nat Clin Pract Endocrinol Metab 2: 395-407
4. David A et al. (2007) An intronic growth hormone receptor mutation causing activation of a pseudoexon is associated with a broad spectrum of growth hormone insensitivity phenotypes. J Clin Endocrinol Metab 92: 655-659
5. Cohen P et al. (2008) Consensus statement on the diagnosis and treatment of children with idiopathic short stature: a summary of the Growth Hormone Research Society, the Lawson Wilkins Pediatric Endocrine Society, and the European Society for Paediatric Endocrinology Workshop. J Clin Endocrinol Metab 93: 4210-4217
6. Wit JM et al. (2008) Idiopathic short stature: management and growth hormone treatment. Growth Horm IGF Res 18: 111-135
7. Rekers-Mombarg LT et al. (1998) Growth hormone therapy with three dosage regimens in children with idiopathic short stature. European Study Group Participating Investigators. J Pediatr 132: 455-460
8. Kamp GA et al. (2002) High dose growth hormone treatment induces acceleration of skeletal maturation and an earlier onset of puberty in children with idiopathic short stature. Arch Dis Child 87: 215-220
9. Allen DB and Fost N (2004) hGH for short stature: ethical issues raised by expanded access. J Pediatr 144: 648-652