Environmental mutagens induced transversions but not transitions in regulatory region of mitochondrial DNA

Journal of Toxicology and Environmental Health - Part A: Current Issues

Volumn 72, Issue 5, 2009, Pages 301-304

  Partridge, Michael A ^a   Huang, Sarah X L ^a,c   Kibriya, Muhammad G ^b   Ahsan, Habibul ^b,c   Davidson, Mercy M ^a   Hei, Tom K ^a,c  

^a New York Presbyterian Columbia University Medical Center   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c Department of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARSENIC; ASBESTOS; MITOCHONDRIAL DNA; MUTAGENIC AGENT; PURINE; PYRIMIDINE; CARCINOGEN; REACTIVE OXYGEN METABOLITE;

ADULT; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; ENVIRONMENTAL EXPOSURE; GAMMA RADIATION; GENETIC POLYMORPHISM; HUMAN; HUMAN CELL; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; OXIDATIVE STRESS; POINT MUTATION; PRIORITY JOURNAL; ULTRAVIOLET RADIATION; ANIMAL; CELL LINE; CHO CELL; CRICETULUS; DNA DAMAGE; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; HAMSTER; LYMPHOCYTE; METABOLISM; MUTATION; POLLUTANT; RADIATION EXPOSURE; SMOKING;

ANIMALS; ARSENIC; ASBESTOS; CARCINOGENS; CELL LINE; CHO CELLS; CRICETINAE; CRICETULUS; DNA DAMAGE; DNA, MITOCHONDRIAL; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; GAMMA RAYS; GENE EXPRESSION REGULATION; HUMANS; LYMPHOCYTES; MUTAGENS; MUTATION; REACTIVE OXYGEN SPECIES; SMOKING; ULTRAVIOLET RAYS;

EID: 60749131341     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287390802526381     Document Type: Article

References (29)

1. Ahsan, H., Chen, Y., Parvez, F., Argos, M., Hussain, A. I., Momotaj, H., Levy D., van Geen, A., Howe, G., and Graziano, J. 2006. Health Effects of Arsenic Longitudinal Study (HEALS): Description of a multidisciplinary epidemiologic investigation. J. Expos. Sci. Environ. Epidemiol. 16:191-205.
2. Aquadro, C. F., and Greenberg, B. D. 1983. Human mitochondrial DNA variation and evolution: analysis of nucleotide sequences from seven individuals. Genetics 103:287-312.
3. Argos, M., Kibriya, M. G., Parvez, F., Jasmine, F., Rakibuz-Zaman, M., and Ahsan, H. 2006. Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. Cancer Epidemiol. Biomarkers Prev. 15:1367-1375.
4. Fliss, M. S., Usadel, H., Caballero, O. L., Wu, L., Buta, M. R., Eleff, S. M., Jen, J., and Sidransky, D. 2000. Facile detection of mitochondrial DNA mutations in tumors and bodily fluids. Science 287:2017-2019.
5. Graziewicz, M. A., Sayer, J. M., Jerina, D. M., and Copeland, W. C. 2004. Nucleotide incorporation by human DNA polymerase gamma opposite benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyguanosine and deoxyadenosine. Nucleic Acids Res. 32:397-405.
6. Harbottle, A., and Birch-Machin, M. A. 2006. Real-time PCR analysis of a 3895 bp mitochondrial DNA deletion in nonmelanoma skin cancer and its use as a quantitative marker for sunlight exposure in human skin. Br. J. Cancer 94:1887-1893.
7. Hei, T. K., Liu, S. X., and Waldren, C. 1998. Mutagenicity of arsenic in mammalian cells: role of reactive oxygen species. Proc. Natl. Acad. Sci. USA 95:8103-8107.
8. Hei, T. K., Wu, L. J., Liu, S. X., Vannais, D., Waldren, C. A., and Randers-Pehrson, G. 1997. Mutagenic effects of a single and an exact number of alpha particles in mammalian cells. Proc. Natl. Acad. Sci. USA 94:3765-3770.
9. Janssen, G. M., Neu, A., t Hart, L. M., van de Sande, C. M., and Antonie Maassen, J. 2006. Novel mitochondrial DNA length variants and genetic instability in a family with diabetes and deafness. Exp. Clin. Endocrinol. Diabetes 114:168-174.
10. Jeronimo, C., Nomoto, S., Caballero, O. L., Usadel, H., Henrique, R., Varzim, G., Oliveira, J., Lopes, C., Fliss, M. S., and Sidransky, D. 2001. Mitochondrial mutations in early stage prostate cancer and bodily fluids. Oncogene 20:5195-5198.
11. Kessel, M., Liu, S. X., Xu, A., Santella, R., and Hei, T. K. 2002. Arsenic induces oxidative DNA damage in mammalian cells. Mol. Cell Biochem. 234-235:301-308.
12. Lee, H. C., Yin, P. H., Yu, T. N., Chang, Y. D., Hsu, W. C., Kao, S. Y., Chi, C. W., Liu, T. Y., and Wei, Y. H. 2001. Accumulation of mitochondrial DNA deletions in human oral tissues -Effects of betel quid chewing and oral cancer. Mutat. Res. 493:67-74.
13. Li, H. H., Aubrecht, J., and Fornace, A. J., Jr. 2007. Toxicogenomics: overview and potential applications for the study of non-covalent DNA interacting chemicals. Mutat. Res. 623:98-108.
14. Liu, S. X., Davidson, M. M., Tang, X., Walker, W. F., Athar, M., Ivanov, V., and Hei, T. K. 2005. Mitochondrial damage mediates genotoxicity of arsenic in mammalian cells. Cancer Res. 65:3236-3242.
15. Mambo, E., Gao, X., Cohen, Y., Guo, Z., Talalay, P., and Sidransky, D. 2003. Electrophile and oxidant damage of mitochondrial DNA leading to rapid evolution of homoplasmic mutations. Proc. Natl. Acad. Sci. USA 100:1838-1843.
16. MITOMAP. 2006. A human mitochondrial genome database. http://www.mitomap.org.
17. Murphy, J. E., Nugent, S., Seymour, C., and Mothersill, C. 2005. Mitochondrial DNA point mutations and a novel deletion induced by direct low-LET radiation and by medium from irradiated cells. Mutat. Res. 585:127-136.
18. Partridge, M. A., Huang, S. X., Hernandez-Rosa, E., Davidson, M. M., and Hei, T. K. 2007. Arsenic induced mitochondrial DNA damage and altered mitochondrial oxidative function: implications for genotoxic mechanisms in mammalian cells. Cancer Res. 67:5239-5247.
19. Piao, C. Q., Liu, L., Zhao, Y. L., Balajee, A. S., Suzuki, M., and Hei, T. K. 2005. Immortalization of human small airway epithelial cells by ectopic expression of telomerase. Carcinogenesis 26:725-731.
20. Pinz, K. G., Shibutani, S., and Bogenhagen, D. F. 1995. Action of mitochondrial DNA polymerase gamma at sites of base loss or oxidative damage. J. Biol. Chem. 270:9202-9206.
21. Polyak, K., Li, Y., Zhu, H., Lengauer, C., Willson, J. K., Markowitz, S. D. Trush, M. A., Kinzler, K. W., and Vogelstein, B. 1998. Somatic mutations of the mitochondrial genome in human colorectal tumours. Nat. Genet. 20:291-293.
22. Salas, A., Yao, Y. G., Macaulay, V., Vega, A., Carracedo, A., and Bandelt, H. J. 2005. A critical reassessment of the role of mitochondria in tumorigenesis. PLoS Med 2 :e296.
23. Vaisman, A., Lim, S. E., Patrick, S. M., Copeland, W. C., Hinkle, D. C., Turchi, J. J., and Chaney, S. G. 1999. Effect of DNA polymerases and high mobility group protein 1 on the carrier ligand specificity for translesion synthesis past platinum-DNA adducts. Biochemistry 38:11026-11039.
24. von Wurmb-Schwark, N., Higuchi, R., Fenech, A. P., Elfstroem, C., Meissner, C., Oehmichen, M., and Cortopassi, G. A. 2002. Quantification of human mitochondrial DNA in a real time PCR. Forens. Sci. Int. 126:34-39.
25. Wang, C. Y., Wang, H. W., Yao, Y. G., Kong, Q. P., and Zhang, Y. P. 2007. Somatic mutations of mitochondrial genome in early stage breast cancer. Int. J. Cancer 121:1253-1256.
26. Warburg, O. 1956. On the origin of cancer cells. Science 123(3191):309-314.
27. Xu, A., Smilenov, L. B., He, P., Masumura, K., Nohmi, T., Yu, Z., and Hei, T. K. 2007. New insight into intrachromosomal deletions induced by chrysotile in the gpt delta transgenic mutation assay. Environ. Health Perspect. 115:87-92.
28. Xu, A., Wu, L. J., Santella, R. M., and Hei, T. K. 1999. Role of oxyradicals in mutagenicity and DNA damage induced by crocidolite asbestos in mammalian cells. Cancer Res. 59:5922-5026.
29. Zanssen, S., and Schon, E. A. 2005. Mitochondrial DNA mutations in cancer. PLoS Med 2:e401.