The triglyceride/high-density lipoprotein cholesterol ratio predicts all-cause mortality in women with suspected myocardial ischemia. A Report From the Women's Ischemia Syndrome Evaluation (WISE)

American Heart Journal

Volumn 157, Issue 3, 2009, Pages 548-555

  Bittner, Vera ^a   Johnson, B Delia ^b   Zineh, Issam ^c   Rogers, William J ^a   Vido, Diane ^d   Marroquin, Oscar C ^e   Bairey Merz, C Noel ^f   Sopko, George ^g  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^c UNIVERSITY OF FLORIDA HEALTH   (United States)

^d ALLEGHENY GENERAL HOSPITAL   (United States)

^e UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^f CEDARS SINAI MEDICAL CENTER   (United States)

^g NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANTIHYPERTENSIVE AGENT; ANTILIPEMIC AGENT; DIURETIC AGENT; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; TRIACYLGLYCEROL; VASODILATOR AGENT;

ADULT; AGE DISTRIBUTION; AGED; ANGIOCARDIOGRAPHY; ARTICLE; CARDIOVASCULAR RISK; CLINICAL EVALUATION; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DIABETES MELLITUS; DISEASE SEVERITY; ETHNIC DIFFERENCE; FEMALE; HEART FAILURE; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HEART MUSCLE REVASCULARIZATION; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MORTALITY; PRIORITY JOURNAL; SMOKING HABIT; STROKE;

ADULT; AGED; CHOLESTEROL, HDL; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; FEMALE; HUMANS; INSULIN RESISTANCE; KAPLAN-MEIERS ESTIMATE; MIDDLE AGED; MYOCARDIAL ISCHEMIA; PREDICTIVE VALUE OF TESTS; PROPORTIONAL HAZARDS MODELS; TRIGLYCERIDES;

EID: 60749126917     PISSN: 00028703     EISSN: 10976744     Source Type: Journal    
DOI: 10.1016/j.ahj.2008.11.014     Document Type: Article

References (26)

1. Rosamond W., Flegal K., Furie K., et al. Heart Disease and Stroke Statistics - 2008 Update. Circulation 117 (2008) e25-e146
2. Bittner V. Perspectives on dyslipidemia and coronary heart disease in women. J Am Coll Cardiol 46 (2005) 1628-1635
3. Hokanson J.E., and Austin M.A. Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level: a meta-analysis of population-based prospective studies. J Cardiovasc Risk 3 (1996) 213-219
4. Sarwar N., Danesh J., Eiriksdottir G., et al. Triglycerides and the risk of coronary heart disease. 10 158 Incident cases among 262 525 participants in 29 western prospective studies. Circulation 115 (2007) 450-458
5. Grundy S.M., Cleeman J.I., Daniels S.R., et al. Diagnosis and management of the metabolic syndrome. An American Heart Association/National Heart, Lung, and Blood Institute scientific statement. Circulation 112 (2005) 2735-2752
6. Assmann G., and Schulte H. Relation of high-density lipoprotein cholesterol and triglycerides to incidence of atherosclerotic coronary artery disease (the PROCAM experience). Prospective Cardiovascular Munster Study. Am J Cardiol 70 (1992) 733-737
7. Manninen V., Tenkanen L., Koskinen P., et al. Joint effects of serum triglyceride and LDL cholesterol and HDL cholesterol concentrations on coronary heart disease risk in the Helsinki Heart Study: implications for treatment. Circulation 85 (1992) 37-45
8. Ballantyne C.M., Olsson A.G., Cook T.J., et al. Influence of low high-density lipoprotein cholesterol and elevated triglyceride on coronary heart disease events and response to simvastatin therapy in 4S. Circulation 104 (2001) 3046-3051
9. Dobiasova M., and Frohlich J. The plasma parameter log (TG/HDL-C) as an atherogenic index: correlation with lipoprotein particle size and esterification rate in apoB-lipoprotein-depleted plasma (FERHDL). Clinical Biochemistry 34 (2001) 583-588
10. Hanak V., Munoz J., Teague J., et al. Accuracy of the triglyceride to high-density lipoprotein cholesterol ratio for prediction of the low-density lipoprotein phenotype B. Am J Cardiol 94 (2004) 219-222
11. McLaughlin T., Reaven T., Abbasi F., et al. Is there a simple way to identify insulin-resistant individuals at increased risk of cardiovascular disease?. Am J Cardiol 96 (2005) 399-404
12. Jiaa L., Long S., Fua M., et al. Relationship between total cholesterol/high-density lipoprotein cholesterol ratio, triglyceride/high-density lipoprotein cholesterol ratio, and high-density lipoprotein subclasses. Metabolism 55 (2006) 1141-1148
13. Gaziano J.M., Hennekens C.H., O'Donnell C.J., et al. Fasting triglycerides, high-density lipoprotein, and risk of myocardial infarction. Circulation 96 (1997) 2520-2525
14. Frohlich J., and Dobiasova M. Fractional esterification rate of cholesterol and ratio of triglycerides to HDL-cholesterol are powerful predictors of positive findings on coronary angiography. Clin Chem 49 (2003) 1873-1880
15. Drexel H., Aczel S., Marte T., et al. Is atherosclerosis in diabetes and impaired fasting glucose driven by elevated LDL cholesterol or by decreased HDL cholesterol?. Diabetes Care 28 (2005) 108-114
16. Shishehbor M.H., Hoogwerf B.J., and Lauer M.S. Association of triglyceride-to-HDL cholesterol ratio with heart rate recovery. Diabetes Care 27 (2004) 936-941
17. Jeppesen J., Hein H.O., Suadicani P., et al. Low triglycerides-high high-density lipoprotein cholesterol and risk of ischemic heart disease. Arch Intern Med 161 (2001) 361-366
18. Asia Pacific Cohort Studies Collaboration. A comparison of lipid variables as predictors of cardiovascular disease in the Asia Pacific region. Ann Epidemiol 15 (2005) 405-413
19. Merz C.N., Kelsey S.F., Pepine C.J., et al. The Women's Ischemia Syndrome Evaluation (WISE) study: protocol, design, methodology, and pilot phase report. J Am Coll Cardiol 33 (1999) 1453-1461
20. Sharaf B.L., Pepine C.J., Kerensky R.A., et al. Detailed angiographic analysis of women with suspected ischemic chest pain (pilot phase data from the NHLBI-sponsored Women's Ischemia Syndrome Evaluation (WISE) study angiographic core laboratory. Am J Cardiol 87 (2001) 937-941
21. Lipid Research Clinics Program. The Manual of Laboratory Operations: Lipid and Lipoprotein Analysis (1974), National Institutes of Health DHEW, Bethesda, MD Publication No.75-628
22. Friedewald W.T., Levy R.I., and Fredrickson D.S. Estimation of the concentration of low-density lipoprotein cholesterol in plasma without use of the preparative ultracentrifuge. Clin Chem 18 (1972) 499-502
23. Hollander M., and Wolfe D.A. Nonparametric Statistical Methods (1973), John Wiley & Sons, New York, NY
24. Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III): final report. Circulation 106 (2002) 3143-3421
25. Sumner A.E., Finley K.B., Genovese D.J., et al. Fasting triglyceride and the triglyceride-HDL cholesterol ratio are not markers of insulin resistance in African Americans. Arch Intern Med 165 (2005) 1395-1400
26. Caroll M.D., Lacher D.A., Sorlie P.D., et al. Trends in serum lipids and lipoproteins of adults, 1960-2002. JAMA 294 (2005) 1773-1781