Sickle cell trait (HbAS) and stunting in children below two years of age in an area of high malaria transmission

Malaria Journal

Volumn 8, Issue 1, 2009, Pages

  Kreuels, Benno ^a,b   Ehrhardt, Stephan ^b   Kreuzberg, Christina ^a   Adjei, Samuel ^c   Kobbe, Robin ^a   Burchard, Gerd D ^a,b   Ehmen, Christa ^b   Ayim, Matilda ^d   Adjei, Ohene ^d   May, Jürgen ^b  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

^c MINISTRY OF HEALTH   (Ghana)

^d KUMASI CENTRE FOR COLLABORATIVE RESEARCH IN TROPICAL MEDICINE   (Ghana)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLOBIN; HEMOGLOBIN S;

ANTHROPOMETRY; ARTICLE; CHILD; CHILDHOOD DISEASE; COHORT ANALYSIS; FEMALE; FOLLOW UP; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; GHANA; HETEROZYGOTE; HUMAN; INCIDENCE; INFANT; MAJOR CLINICAL STUDY; MALARIA; MALE; MALNUTRITION; PARASITE TRANSMISSION; POPULATION; PRESCHOOL CHILD; SICKLE CELL TRAIT; AGE; BLOOD; CONFIDENCE INTERVAL; GENETICS; GROWTH DISORDER; HEMOGLOBIN AS; PREVALENCE; RISK; RISK FACTOR;

AGE FACTORS; BETA-GLOBINS; CHILD, PRESCHOOL; COHORT STUDIES; CONFIDENCE INTERVALS; FOLLOW-UP STUDIES; GENOTYPE; GHANA; GROWTH DISORDERS; HEMOGLOBIN, SICKLE; HUMANS; INCIDENCE; INFANT; MALARIA; MALE; MALNUTRITION; ODDS RATIO; PREVALENCE; RISK FACTORS; SICKLE CELL TRAIT;

EID: 60749114477     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-8-16     Document Type: Article

References (17)

1. Hemoglobin variants and disease manifestations in severe falciparum malaria. J May JA Evans C Timmann C Ehmen W Busch T Thye T Agbenyega RD Horstmann, JAMA 2007 297 2220 2226 10.1001/jama.297.20.2220 17519411
2. An immune basis for malaria protection by the sickle cell trait. TN Williams TW Mwangi DJ Roberts ND Alexander DJ Weatherall S Wambua M Kortok RW Snow K Marsh, PLos Med 2005 2 e128 15916466 10.1371/journal.pmed.0020128
3. Protective effects of the sickle cell gene against malaria morbidity and mortality. M Aidoo DJ Terlouw MS Kolczak PD McElroy FO ter Kuile S Kariuki BL Nahlen AA Lal V Udhayakumar, Lancet 2002 359 1311 1312 10.1016/S0140-6736(02) 08273-9 11965279
4. Malaria and nutritional status in children living on the coast of Kenya. AM Nyakeriga M Troye-Blomberg AK Chemtai K Marsh TN Williams, Am J Clin Nutr 2004 80 1604 1610 15585775
5. Impact of permethrin-treated bed nets on malaria, anemia, and growth in infants in an area of intense perennial malaria transmission in western Kenya. FO ter Kuile DJ Terlouw SK Kariuki PA Phillips-Howard LB Mirel WA Hawley JF Friedman YP Shi MS Kolczak AA Lal JM Vulule BL Nahlen, Am J Trop Med Hyg 2003 68 68 77 12749488
6. Malaria, anemia, and malnutrition in African children - defining intervention priorities. S Ehrhardt GD Burchard C Mantel JP Cramer S Kaiser M Kubo RN Otchwemah U Bienzle FP Mockenhaupt, J Infect Dis 2006 194 108 114 10.1086/504688 16741889
7. Malnutrition as an underlying cause of childhood deaths associated with infectious diseases in developing countries. AL Rice L Sacco A Hyder RE Black, Bull World Health Organ 2000 78 1207 1221 11100616
8. Severity and timing of stunting in the first two years of life affect performance on cognitive tests in late childhood. MA Mendez LS Adair, J Nutr 1999 129 1555 1562 10419990
9. Maternal and child undernutrition: consequences for adult health and human capital. C Victora L Adair C Fall P Hallal R Martorell L Richter H Sachdev, Lancet 2008 371 340 357 18206223 10.1016/S0140-6736(07)61692-4
10. Growth and development in children with sickle-cell trait. A prospective study of matched pairs. MS Kramer Y Rooks HA Pearson, N Engl J Med 1978 299 686 689 683252
11. Growth status of children with and without sickle cell trait. N Rehan, Clin Pediatr (Phila) 1981 20 11 705 709 10.1177/000992288102001103 7297011
12. A comparison of the physical and intellectual development of black children with and without sickle-cell trait. MK McCormack S Scarr-Salapatek H Polesky W Thompson SH Katz WB Barker, Pediatrics 1975 56 1021 1025 172854
13. A randomized controlled trial of extended intermittent preventive antimalarial treatment in infants. R Kobbe C Kreuzberg S Adjei B Thompson I Langefeld PA Thompson HH Abruquah B Kreuels M Ayim W Busch F Marks K Amoah E Opoku C Meyer O Adjei J May, Clin Infect Dis 2007 45 16 25 10.1086/518575 17554695
14. Spatial variation of malaria incidence in young children from a geographically homogeneous area with high endemicity. B Kreuels R Kobbe S Adjei C Kreuzberg C Von Reden K Bater S Klug W Busch O Adjei J May, J Infect Dis 2008 197 85 93 10.1086/524066 18171290
15. WHO Child Growth Standards based on length/height, weight and age. WMGRS Group, Acta Paediatrica 2006 450 76 85 16817681
16. Rapid beta-globin genotyping by multiplexing probe melting temperature and color. MG Herrmann SF Dobrowolski CT Wittwer, Clin Chem 2000 46 425 428 10702535
17. Sickle cell trait and the risk of Plasmodium falciparum malaria and other childhood diseases. TN Williams TW Mwangi S Wambua ND Alexander M Kortok RW Snow K Marsh, J Infect Dis 2005 192 178 186 10.1086/430744 15942909