Design and evaluation of transdermal drug delivery system for curcumin as an anti-inflammatory drug

Drug Development and Industrial Pharmacy

Volumn 35, Issue 2, 2009, Pages 234-242

  Patel, Nikunjana A ^a   Patel, Natvar J ^a   Patel, Rakesh P ^a  

^a GANPAT UNIVERSITY   (India)

Author keywords

Curcumin; In vitro permeation study; Permeation enhancer; Transdermal film

Indexed keywords

ANTIINFLAMMATORY AGENT; CURCUMIN; OLEIC ACID; POLYMER;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG RESEARCH; DRUG SCREENING; HYDROPHILICITY; HYDROPHOBICITY; IN VITRO STUDY; INFRARED SPECTROSCOPY; KINETICS; NONHUMAN; PHYSICAL CHEMISTRY; RAT; TENSILE STRENGTH;

ADMINISTRATION, CUTANEOUS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CARRAGEENAN; CELLULOSE; CURCUMIN; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; DRUG INCOMPATIBILITY; DRUG STABILITY; EDEMA; EXCIPIENTS; HYDROPHOBICITY; KINETICS; METHYLCELLULOSE; PERMEABILITY; RATS; RATS, WISTAR; SKIN; SKIN ABSORPTION; TENSILE STRENGTH; VEHICLES;

EID: 60749106975     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.1080/03639040802266782     Document Type: Article

References (36)

1. Anto, R. J., Kuttan, G., Babu, K. V. D., Rajasekharan, K. N., & Kuttan, R. (1998). Antiinflammatory activity of natural and synthetic curcuminoids. Pharm. Pharmacol. Commun., 4, 103-106.
2. Arora, P., & Mukherjee, P. (2002). Design, development, physicochemical, and in vitro and in vivo evaluation of transdermal patches containing diclofenac diethylammonium salt. J. Pharm. Sci., 91, 2076-2089.
3. Asai, A., & Miyazawa, T. (2000). Occurrence of orally administered curcuminoid as glucuronide and glucuronide/sulfate conjugates in rat plasma. Life Sci., 67, 2785-2793.
4. Bangham, A. D., Hill, M. W., & Miller, N. G. A. (1974). Preparation and use of liposomes as models of biological membranes. In E. D. Korn (Ed.), Methods in membrane biology (Vol. 1, Chapter 1, pp. 1-64). New York: Plenum Press.
5. Cheng, A. L., Lin, J. K., Hsu, M. M., Lin, J. T., Hsu, M. M., Ho, Y. F., Shen, T. S., Ko, J. Y., Lin, J. T., Lin, B. R., Wu, M. S., Yu, H. S., Jee, S. H., Chen, G. S., Chen, T. M., Chen, C. A., Lai, M. K., Pu, Y. S., Pan, M. H., Wang, U. J., Tsai, C. C., & Hsieh, C. Y. (2001). Phase I chemoprevention clinical trial of curcumin, a chemopreventive agent, in patients with high risk or pre-malignant lesions. Anticancer Res., 21, 2895-2900.
6. Chi, S. C., Park, E. S., & Kim, H. (1995). Effect of penetration enhancers on flurbiprofen permeation though rat skin. Int. J. Pharm., 126, 267-274.
7. Chien, Y. W. (1987). Transdermal therapeutic system. In J. R. Robinson, & V. H. L. Lee (Eds.), Controlled drug delivery fundamentals and applications (2nd ed., pp. 524-552). New York: Marcel Dekker, Inc.
8. Cooper, E. R. (1984). Increased skin permeability for lipophilic molecules. Pharm. Sci., 73, 1153-1156.
9. Draize, J. H., Woodward, G., & Calvery, H. O. (1944). Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membranes. J. Pharmacol. Exp. Ther., 82, 377-379.
10. Goodman, M., & Barry, B. W. (1988). Action of penetration enhancers on human skin as assessed by the permeation of model drugs 5-fluorouracil and estradiol. I. Infinite dose technique. J. Invest. Dermatol., 91, 323-327.
11. Goodman, M., & Barry, B. W. (1989). Lipid-protein-partitioning (LPP) theory of skin enhancer activity: Finite dose technique. Int. J. Pharm., 57, 29-40.
12. Gupta, R., & Mukherjee, B. (2003). Development and in vitro evaluation of diltiazem hydrochloride transdermal patches based on povidone-ethyl cellulose matrices. Drug Dev. Ind. Pharm., 29, 1-7.
13. Harris, J. M., & Spencer, P. S. J. (1962). A modified plythesmographic apparatus for recording volume changes in rat paw. J. Pharm. Pharmacol., 14, 464-466.
14. Hu, J. H., & Zhu, Y. (1996). Effect of enhancers on the permeation of ketoprofen in-vitro. Yao-Hsueh-Hsueh-Pao, 31, 48-53.
15. Huang, M. T., Smart, R. C., Wong, C. Q., & Conney, A. H. (1988). Inhibitory effect of curcumin, chlorogenic acid, caffeic acid, and ferulic acid on tumor promotion in mouse skin by 12-O-tetradecanoylphorbol-13-acetate. Cancer Res., 48(21), 5941-5946.
16. Katayose, S., & Kataoka, K. (1997). Water-soluble polyion complex associates of DNA and poly(ethylene glycol)-poly(L-lysine) block copolymer. Bioconjug. Chem., 8, 702-707.
17. Keith, A. D. (1983). Polymer matrix consideration for transdermal devices. Drug Dev. Ind. Pharm., 9, 605-621.
18. Kim, D. D., & Chien, Y. W. (1996). Transdermal delivery of dideoxynucleoside-type anti-HIV drugs. 2. The effect of vehicle and enhancer on skin permeation. J. Pharm. Sci., 85, 214-219.
19. Kumar, V., Lewis, S. A., Mutalik, S., Shenoy, D. B., Venkatesh., M., & Udupa, N. (2002). Biodegradable microspheres of curcumin for treatment of inflammation. Indian J. Physiol. Pharmacol., 46(2), 209-217.
20. Kusum, D. V., Saisivam, S., Maria, G. R., & Deepti, P. U. (2003). Design and evaluation of matrix diffusion controlled transdermal patches of verapamil hydrochloride. Drug Dev. Ind. Pharm., 29, 495-503.
21. Limpongsa, E., & Umprayn, K. (2008). Preparation and evaluation of diltiazem hydrochloride diffusion-controlled transdermal delivery system. AAPS PharmSciTech., 9(2), 464-470.
22. Misra, A. N. (1997). Controlled and novel drug delivery. In N. K. Jain (Ed.), Transdermal drug delivery (pp. 100-101). New Delhi, India: CBS Publisher and Distributor.
23. Mutalik, S., & Udupa, N. (2004). Glibenclamide transdermal patches: Physicochemical, pharmacodynamic, and pharmacokinetic evaluations. J. Pharm. Sci., 93, 1577-1594.
24. Namdeo, A., & Jain, N. K. (2002). Liquid crystalline pharmacogel based enhanced transdermal delivery of propranolol hydrochloride. J. Control. Release, 82, 223-236.
25. Rao, P. R., & Diwan, P. V. (1998). Formulation and in vitro evaluation of polymeric films of diltiazem hydrochloride and indomethacin for transdermal administration. Drug Dev. Ind. Pharm., 24, 327-336.
26. Rao, D. S., Sekhara, N. C., Satyanarayana, M. N., & Srinivasan, M. (1970). Effect of curcumin on serum and liver cholesterol levels in the rat. J. Nutr., 100(11), 1307-1315.
27. Ravindranath, V., & Chandrasekhara, N. (1980). Absorption and tissue distribution of curcumin in rats. Toxicology, 16, 259-265.
28. Ritger, P. L., & Peppas, N. A. (1987). A simple equation for description of solute release, I: Fickian and non-fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs. J. Control. Release, 5, 23-26.
29. Sakellariou, P., Rowe, R. C., & White, E. F. T. (1986). An evaluation of the interaction and plasticizing efficiency of the polyethylene glycols in ethyl cellulose and hydroxypropyl methylcellulose films using the torsional braid pendulum. Int. J. Pharm., 31, 55-64.
30. Sreejayan Rao, M. N. (1994). Curcuminoids as potent inhibitors of lipid peroxidation. J. Pharm. Pharmacol., 46(12), 1013-1016.
31. Srimol, R. C., & Dhawan, B. N. (1973). Pharmacology of diferuloyl methane (curcumin), a non-steroidal anti-inflammatory agent. J. Pharm. Pharmacol., 25, 447-452.
32. Tiyaboonchai, W., Tungpradit, W., & Plianbangchang, P. (2007). Formulation and characterization of curcuminoids loaded solid lipid nanoparticles. Int. J. Pharm., 337(1-2), 299-306.
33. Vidyalakshmi, K., Rashmi, K. N., Pramodkumar, T. M., & Siddaramaiah, K. (2004). Studies on formulation and in vitro evaluation of PVA/chitosan blend films for drug delivery. J. Macromol. Sci. Pure Appl. Chem., 41(10), 1115-1122.
34. Wade, A., & Weller, P. J. (1994). Handbook of pharmaceutical excipients (pp. 362-366). Washington, DC: American Pharmaceutical Publishing Association.
35. Wang, X., Jiang, Y., Wang, Y.-W., Huang, M.-T., Ho, C.-T., & Huang, Q. (2008). Enhancing anti-inflammation activity of curcumin through O/W nanoemulsions. Food Chem., 108(2), 419-424.
36. Winter, C. A., Risley, E. A., & Nuss, G. W. (1962). Carrageenan induced edema in hind paw of the rat as an assay for anti-inflammatory drugs. Proc. Soc. Exp. Biol. Med., 111, 544-547.