Mutagenesis identifies the critical regions and amino acid residues of suid herpesvirus 1 DNA-binding protein required for DNA binding and strand invasion

Virus Research

Volumn 140, Issue 1-2, 2009, Pages 147-154

  Wu, Shih Lu ^a   Li, Chia Cheng ^a   Ho, Tin Yun ^a,b   Hsiang, Chien Yun ^a  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Chemical modification; DNA binding; DNA binding protein; Site directed mutagenesis; Strand invasion; Suid herpesvirus 1

Indexed keywords

ACETIC ANHYDRIDE; AMINO ACID; DNA BINDING PROTEIN; LYSINE;

ARTICLE; DNA BINDING; DNA STRAND; HERPES SIMPLEX VIRUS 1; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; DNA, SINGLE-STRANDED; DNA, VIRAL; DNA-BINDING PROTEINS; HERPESVIRUS 1, SUID; LYSINE; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; VIRAL PROTEINS;

SUID HERPESVIRUS 1;

EID: 60749095404     PISSN: 01681702     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.virusres.2008.11.013     Document Type: Article

References (33)

1. Bataille D., and Epstein A.L. Herpes simplex virus type 1 replication and recombination. Biochimie 77 (1995) 787-795
2. Baumann P., Benson F.E., and West S.C. Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro. Cell 87 (1996) 757-766
3. Ben-Porat T., Veach R.A., and Ihara S. Localization of the regions of homology between the genomes of herpes simplex virus type 1 and pseudorabies virus. Virology 127 (1983) 194-204
4. Ben-Porat T., Veach R.A., and Hampl H. Functions of the major nonstructural DNA binding protein of a herpesvirus (pseudorabies). Virology 124 (1983) 411-424
5. Bortner C., Hernandez T.R., Lehman I.R., and Griffith J. Herpes simplex virus 1 single-strand DNA-binding protein (ICP8) will promotes homologous pairing and strand transfer. J. Mol. Biol. 231 (1993) 241-250
6. Bryant F.R., and Lehman I.R. On the mechanism of renaturation of complementary DNA strands by the RecA protein of Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 82 (1985) 297-301
7. Dutch R.E., Bruckner R.C., Mocarski E.S., and Lehman I.R. Herpes simplex virus type 1 recombination: role of DNA replication and viral a sequences. J. Virol. 66 (1992) 277-285
8. Dutch R.E., and Lehman I.R. Renaturation of complementary DNA strands by herpes simplex virus type 1 ICP8. J. Virol. 67 (1993) 6945-6949
9. Gao M., Boucgey J., Curtin K., and Knipe D.M. Genetic identification of a portion of the herpes simplex virus ICP8 protein required for DNA-binding. Virology 163 (1988) 319-329
10. Glazenburg K.L., Moormann R.J.M., Kimman T.G., Gielkens A.L.J., and Peeters B.P.H. In vivo recombination of pseudorabies virus strains in mice. Virus Res. 34 (1994) 115-126
11. Heyer W.D., Evans D.H., and Kolodner R.D. Renaturation of DNA by Saccharomyces cerevisiae protein that catalyzes homologous pairing and strand exchange. J. Biol. Chem. 263 (1988) 15189-15195
12. Ho T.Y., Wu S.L., Hsiang C.H., Chang T.J., and Hsiang C.Y. Identification of a DNA-binding domain and an active-site residue of pseudorabies virus DNase. Biochem. J. 346 (2000) 441-445
13. Hsiang C.Y., Ho T.Y., Hsiang C.H., and Chang T.J. Recombinant pseudorabies virus DNase exhibits a RecBCD-like catalytic function. Biochem. J. 330 (1998) 55-59
14. Hsiang C.Y. Pseudorabies virus DNA-binding protein stimulates the exonuclease activity and regulates the processivity of pseudorabies virus DNase. Biochem. Biophys. Res. Commun. 293 (2002) 1301-1308
15. Kintner R.L., Allan R.W., and Brandt C.R. Recombinants are isolated at high frequency following in vivo mixed ocular infection with two avirulent herpes simplex virus type 1 strains. Arch. Virol. 140 (1995) 231-244
16. Kosinski J., Cymerman I.A., Feder M., Kurowski M.A., Sasin J.M., and Bujnicki J.M. A 'FRankenstein's monster' approach to comparative modeling: merging the finest fragments of fold-recognition models and iterative model refinement aided by 3D structure evaluation. Proteins 53 (2003) 369-379
17. Kurowski M.A., and Bujnicki J.M. GeneSilico protein structure prediction meta-server. Nucleic Acids Res. 31 (2003) 3305-3307
18. Leinbach S.S., and Heath L.S. A carboxyl-terminal peptide of the DNA-binding protein ICP8 of herpes simplex virus contains a single-stranded DNA-binding site. Virology 166 (1988) 10-16
19. Li Z., Golub E.I., Gupta R., and Radding C.M. Recombination activities of HsDmc1 protein, the meiotic human homolog of RecA protein. Proc. Natl. Acad. Sci. U.S.A. 94 (1997) 11221-11226
20. Mapelli M., Mühleisen M., Persico G., van der Zandt H., and Tucker P.A. The 60-residue C-terminal region of the single-stranded DNA binding protein on herpes simplex virus type 1 is required for cooperative DNA binding. J. Virol. 74 (2000) 8812-8822
21. Mapelli M., Panjikar S., and Tucker P.A. The crystal structure of the herpes simplex virus 1 ssDNA-binding protein suggests the structural basis for flexible, cooperative single-stranded DNA binding. J. Biol. Chem. 280 (2005) 2990-2997
22. McEntee K., Weinstock G.M., and Lehman I.R. Initiation of general recombination catalyzed in vitro by the RecA protein of Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 76 (1979) 2615-2619
23. Neale G.A.M., and Kitchingman G.R. Conserved region 3 of the adenovirus type 5 DNA-binding protein is important for interaction with single stranded DNA. J. Virol. 64 (1990) 630-638
24. Nimonkar A.V., and Boehmer P.E. The herpes simplex virus type-1 single-strand DNA-binding protein (ICP8) promotes strand invasion. J. Biol. Chem. 278 (2003) 9678-9682
25. Norris D., and Kolodner R. Interaction of a Saccharomyces cerevisiae strand exchange stimulatory factor with DNA. Biochemistry 29 (1990) 7911-7917
26. Reuven N.B., Staire A.E., Myers R.S., and Weller S.K. The herpes simplex virus type 1 alkaline nuclease and single-stranded DNA binding protein mediate strand exchange in vitro. J. Virol. 77 (2003) 7425-7433
27. Ruyechan W.T., and Olson J.W. Surface lysine and tyrosine residues are required for interaction of the major herpes simplex virus type 1 DNA-binding protein with single stranded DNA. J. Virol. 66 (1992) 6273-6279
28. Shan Q., Cox M.M., and Inman R.B. DNA strand exchange promoted by RecA K72R. J. Biol. Chem. 271 (1996) 5712-5724
29. Singleton M.R., Wentzell L.M., Liu Y., West S.C., and Wigley D.B. Structure of the single-strand annealing domain of human RAD52 protein. Proc. Natl. Acad. Sci. U.S.A. 99 (2002) 13492-13497
30. Tsugita A., and Kneale G.G. Identification of lysine residues at the binding site of bacteriophage-Pf1 DNA-binding protein. Biochem. J. 228 (1985) 193-199
31. Wang Y., and Hall J. Characterization of a major DNA-binding domain in the herpes simplex virus type 1 DNA-binding protein (ICP8). J. Virol. 64 (1990) 2082-2089
32. Wilkinson D.E., and Weller S.K. The role of DNA recombination in herpes simplex virus DNA replication. IUBMB Life 55 (2003) 451-458
33. Wu S.L., Hsiang C.Y., Ho T.Y., and Chang T.J. Identification, expression, and characterization of the pseudorabies virus DNA-binding protein gene and gene product. Virus Res. 56 (1998) 1-9