ErbB4 regulates surfactant synthesis and proliferation in adult rat pulmonary epithelial cells

Experimental Lung Research

Volumn 35, Issue 1, 2009, Pages 29-47

  Liu, Washa ^a   Volpe, Mary Ann V ^a   Zscheppang, Katja ^a,b   Nielsen, Heber C ^a   Dammann, Christiane E L ^a,b  

^a TUFTS MEDICAL CENTER   (United States)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Mesenchyme epithelial communication; Neuregulin; Pulmonary surfactant; Small interfering RNA

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 4; LUNG SURFACTANT; NEU DIFFERENTIATION FACTOR; PHOSPHOLIPID; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; EPITHELIUM CELL; FIBROBLAST; HOMEOSTASIS; LUNG ALVEOLUS CELL; LUNG ALVEOLUS EPITHELIUM; NONHUMAN; PHOSPHOLIPID SYNTHESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; REGULATORY MECHANISM; SYNTHESIS;

ANIMALS; CELL COUNT; CELL LINE; CELL PROLIFERATION; CULTURE MEDIA, CONDITIONED; DOWN-REGULATION; FEMALE; GENE EXPRESSION; GENE TRANSFER, HORIZONTAL; MALE; NEUREGULIN-1; PHOSPHOLIPIDS; PHOSPHORYLATION; PULMONARY SURFACTANT-ASSOCIATED PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, EPIDERMAL GROWTH FACTOR; RESPIRATORY MUCOSA; RNA, SMALL INTERFERING;

EID: 60749093714     PISSN: 01902148     EISSN: 15210499     Source Type: Journal    
DOI: 10.1080/01902140802395757     Document Type: Article

References (48)

1. Plowman GD, Culouscou JM, Whitney GS, Green JM, Carlton GW, Foy L, Neubauer MG, Shoyab M: Ligand-specific activation of HER4/p180erbB4, a fourth member of the epidermal growth factor receptor family. Proc Natl Acad Sci U S A. 1993;90:1746-1750.
2. Ramadurai SM, Chen WY, Yerozolimsky GB, Zagami M, Dammann CE, Nielsen HC: Cell-specific and developmental expression of phospholipase C-gamma and diacylglycerol in fetal lung. Am J Physiol Lung Cell Mol Physiol. 2003;284:L808-L816.
3. Schulze WX, Deng L, Mann M: Phosphotyrosine interactome of the ErbB-receptor kinase family. Mol Syst Biol. 2005;1:1-13.
4. Lemmens K, Segers VF, Demolder M, De Keulenaer GW: Role of neuregulin-1/ErbB2 signaling in endothelium-cardiomyocyte cross-talk. J Biol Chem. 2006;281:19469-19477.
5. Chang H, Riese DJ, Gilbert W, Stern DF, McMahan UJ: Ligands for ErbB-family receptors encoded by a neuregulin-like gene. Nature. 1997;387:509-512.
6. Srinivasan R, Poulsom R, Hurst HC, Gullick WJ: Expression of the c-erbB-4/HER4 protein and mRNA in normal human fetal and adult tissues and in a survey of nine solid tumour types. J Pathol. 1998;185:236-245.
7. Naresh A, Long W, Vidal GA, Wimley WC, Marrero L, Sartor CI, Tovey S, Cooke TG, Bartlett JM, Jones FE: The ERBB4/HER4 intracellular domain 4ICD is a BH3-only protein promoting apoptosis of breast cancer cells. Cancer Res. 2006;66:6412-6420.
8. msellem-Ouazana D, Bieche I, Tozlu S, Botto H, Debre B, Lidereau R: Gene expression profiling of ERBB receptors and ligands in human transitional cell carcinoma of the bladder. J Urol. 2006;175:1127-1132.
9. Normanno N, De LA, Bianco C, Strizzi L, Mancino M, Maiello MR, Carotenuto A, De FG, Caponigro F, Salomon DS: Epidermal growth factor receptor (EGFR) signaling in cancer. Gene. 2006;366:2-16.
10. Starr A, Greif J, Vexler A, shkenazy-Voghera M, Gladesh V, Rubin C, Kerber G, Marmor S, Lev-Ari S, Inbar M, Yarden Y, Ben-Yosef R: ErbB4 increases the proliferation potential of human lung cancer cells and its blockage can be used as a target for anti-cancer therapy. Int J Cancer. 2006;119:269-274.
11. Iwamoto R, Mekada E: ErbB and HB-EGF signaling in heart development and function. Cell Struct Funct. 2006;31:1-14.
12. Bovetti S, De MS, Gambarotta G, Fasolo A, Perroteau I, Puche AC, Bovolin P: Differential expression of neuregulins and their receptors in the olfactory bulb layers of the developing mouse. Brain Res. 2006;1077:37-47.
13. Golding JP, Sobieszczuk D, Dixon M, Coles E, Christiansen J, Wilkinson D, Gassmann M: Roles of erbB4, rhombomere-specific, and rhombomere-independent cues inmaintaining neural crest-free zones in the embryonic head. Dev Biol. 2004;266:361-372.
14. Gassmann M, Casagranda F, Orioli D, Simon H, Lai C, Klein R, Lemke G: Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor. Nature. 1995;378:390-394.
15. Meyer D, Birchmeier C: Multiple essential functions of neuregulin in development. Nature. 1995;378:386-390.
16. Lee KF, Simon H, Chen H, Bates B, Hung MC, Hauser C: Requirement for neuregulin receptor erbB2 in neural and cardiac development. Nature. 1995;378:394-398.
17. Olayioye MA, Neve RM, Lane HA, Hynes NE: The ErbB signaling network: receptor heterodimerization in development and cancer. EMBO J. 2000;19:3159-3167.
18. Ruocco S, Lallemand A, Tournier JM, Gaillard D: Expression and localization of epidermal growth factor, transforming growth factor-alpha, and localization of their common receptor in fetal human lung development. Pediatr Res. 1996;39:448-455.
19. Dammann CE, Nielsen HC: Carraway KL III: Role of neuregulin-1 beta in the developing lung. Am J Respir Crit Care Med. 2003;167:1711-1716.
20. Dammann CE, Nielsen HC: Regulation of the epidermal growth factor receptor in fetal rat lung fibroblasts during late gestation. Endocrinology. 1998;139:1671-1677.
21. Nielsen HC, Martin A, Volpe MV, Hatzis D, Vosatka RJ: Growth factor control of growth and epithelial differentiation in embryonic lungs. Biochem Mol Med. 1997;60:38-48.
22. Nielsen HC, Kellogg CK, Doyle CA: Development of fibroblast-type-II cell communications in fetal rabbit lung organ culture. Biochim Biophys Acta. 1992;1175:95-99.
23. Nielsen HC: Epidermal growth factor influences the developmental clock regulating maturation of the fetal lung fibroblast. Biochim Biophys Acta. 1989;1012:201-206.
24. Dammann CE, Nassimi N, Liu W, Nielsen HC: ErbB receptor regulation by dexamethasone in mouse type II epithelial cells. Eur Respir J. 2006;28:1117-1123.
25. Dammann CE, Ramadurai SM, McCants DD, Pham LD, Nielsen HC: Androgen regulation of signaling pathways in late fetal mouse lung development. Endocrinology. 2000;141:2923-2929.
26. Rosenblum DA, Volpe MV, Dammann CE, Lo YS, Thompson JF, Nielsen HC: Expression and activity of epidermal growth factor receptor in late fetal rat lung is cell- and sex-specific. Exp Cell Res. 1998;239:69-81.
27. Ramadurai SM, Nielsen HC, Chen Y, Hatzis D, Sosenko IR: Differential effects in vivo of thyroid hormone on the expression of surfactant phospholipid, surfactant protein mRNA and antioxidant enzyme mRNA in fetal rat lung. Exp Lung Res. 1998;24:641-657.
28. Liu W, Zscheppang K, Murray S, Nielsen HC, Dammann CE:The ErbB4 receptor in fetal rat lung fibroblasts and epithelial type II cells. Biochim Biophys Acta. 2007;1772:737-747.
29. Zscheppang K, Korenbaum E, Bueter W, Ramadurai SM, Nielsen HC: Dammann CE, ErbB receptor dimerization, localization, and co-localization in mouse lung type II epithelial cells. Pediatr Pulmonol. 2006;41:1205-1212.
30. Fitzpatrick VD, Pisacane PI, Vandlen RL, Sliwkowski MX: Formation of a high affinity heregulin binding site using the soluble extracellular domains of ErbB2 with ErbB3 or ErbB4. FEBS Lett. 1998;431:102-106.
31. Zscheppang K, Liu W, Volpe MV, Nielsen HC, Dammann CE: ErbB4 regulates fetal surfactant phospholipid synthesis in primary fetal rat type II cells. Am J Physiol Lung Cell Mol Physiol. 2007;293:L429-L435.
32. Tidcombe H, Jackson-Fisher A, Mathers K, Stern DF, Gassmann M, Golding JP: Neural and mammary gland defects in ErbB4 knockout mice genetically rescued from embryonic lethality. Proc Natl Acad Sci U S A. 2003;100:8281-8286.
33. Purevdorj E, Zscheppang K, Hoymann HG, Braun A, von MD, Brinkhaus MJ, Schmiedl A, Dammann CE: ErbB4 deletion leads to changes in lung function and structure similar to bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol. 2008;294:L516-L522.
34. Klein JM, Nielsen HC: Sex-specific differences in rabbit fetal lung maturation in response to epidermal growth factor. Biochim Biophys Acta. 1992;1133:121-126.
35. Carraway KL, III, Cantley LC, A neu acquaintance for erbB3 and erbB4: a role for receptor heterodimerization in growth signaling. Cell. 1994;78:5-8.
36. Nielsen HC, Torday JS: Anatomy of fetal rabbit gonads and the sexing of fetal rabbits. Lab Anim. 1983;17:148-150.
37. Douglas WH, Sommers-Smith SK, Johnston JM: Phosphatidate phosphohydrolase activity as a marker for surfactant synthesis in organotypic cultures of type II alveolar pneumonocytes. J Cell Sci. 1983;60:199-207.
38. Funkhouser JD, Cheshire LB, Ferrara TB, Peterson RD: Monoclonal antibody identification of a type II alveolar epithelial cell antigen and expression of the antigen during lung development. Dev Biol. 1987;119:190-198.
39. Vij N, Zeitlin PL, Regulation of the ClC-2 lung epithelial chloride channel by glycosylation of SP1. Am J Respir Cell Mol Biol. 2006;34:754-759.
40. Zhang H, Dickinson DA, Liu RM, Forman HJ: 4-Hydroxynonenal increases gamma-glutamyl transpeptidase gene expression through mitogen-activated protein kinase pathways. Free Radic Biol Med. 2005;38:463-471.
41. Douglas WH, Kaighn ME: Clonal isolation of differentiated rat lung cells. In Vitro. 1974;10:230-237.
42. Veldhuizen R, Possmayer F: Phospholipid metabolism in lung surfactant. Subcell Biochem. 2004;37:359-388.
43. Shannon JM, Pan T, Nielsen LD, Edeen KE, Mason RJ: Lung fibroblasts improve differentiation of rat type II cells in primary culture. Am J Respir Cell Mol Biol. 2001;24:235-244.
44. Torday JS, Sun H, Wang L, Torres E, Sunday ME, Rubin LP: Leptin mediates the parathyroid hormone-related protein paracrine stimulation of fetal lung maturation. Am J Physiol Lung Cell Mol Physiol. 2002;282:L405-L410.
45. Wang G, Davidson BL, Melchert P, Slepushkin VA, van Es HH, Bodner M, Jolly DJ, McCray PB Jr: Influence of cell polarity on retrovirus-mediated gene transfer to differentiated human airway epithelia. J Virol. 1998;72:9818-9826.
46. Nielsen HC, Kirk WO, Sweezey N, Torday JS: Coordination of growth and differentiation in the fetal lung. Exp Cell Res. 1990;188:89-96.
47. Adamson IY, King GM: Sex differences in development of fetal rat lung. I. Autoradiographic and biochemical studies. Lab Invest. 1984;50:456-460.
48. Post M, Smith BT: Effect of fibroblast-pneumonocyte factor on the synthesis of surfactant phospholipids in type II cells from fetal rat lung. Biochim Biophys Acta. 1984;793:297-299.