-
1
-
-
0001144847
-
In Morphol
-
Edited by Gegenbaur C
-
Rabl C: Über Zelltheilung. In Morphol. Jahrbuch. Edited by Gegenbaur C. 1885:214-330.
-
(1885)
Jahrbuch
, pp. 214-330
-
-
Rabl, C.1
Zelltheilung, U.2
-
2
-
-
0001169778
-
Die blastermerenkerne von Ascaris megalocephala und die theorie der chromosomenindividualität
-
Boveri T. Die blastermerenkerne von Ascaris megalocephala und die theorie der chromosomenindividualität. Arch. Zellforschung 3 (1909) 181
-
(1909)
Arch. Zellforschung
, vol.3
, pp. 181
-
-
Boveri, T.1
-
3
-
-
0029969424
-
Specific interactions of chromatin with the nuclear envelope: positional determination within the nucleus in Drosophila melanogaster
-
Marshall W.F., Dernburg A.F., Harmon B., Agard D.A., and Sedat J.W. Specific interactions of chromatin with the nuclear envelope: positional determination within the nucleus in Drosophila melanogaster. Mol Biol Cell 7 (1996) 825-842
-
(1996)
Mol Biol Cell
, vol.7
, pp. 825-842
-
-
Marshall, W.F.1
Dernburg, A.F.2
Harmon, B.3
Agard, D.A.4
Sedat, J.W.5
-
4
-
-
0037165965
-
Visualizing chromatin dynamics in interphase nuclei
-
Gasser S.M. Visualizing chromatin dynamics in interphase nuclei. Science 296 (2002) 1412-1416
-
(2002)
Science
, vol.296
, pp. 1412-1416
-
-
Gasser, S.M.1
-
5
-
-
0033118342
-
Nuclear compartments and gene regulation
-
Cockell M., and Gasser S.M. Nuclear compartments and gene regulation. Curr Opin Genet Dev 9 (1999) 199-205
-
(1999)
Curr Opin Genet Dev
, vol.9
, pp. 199-205
-
-
Cockell, M.1
Gasser, S.M.2
-
6
-
-
0032490917
-
Perinuclear localization of chromatin facilitates transcriptional silencing
-
Andrulis E.D., Neiman A.M., Zappulla D.C., and Sternglanz R. Perinuclear localization of chromatin facilitates transcriptional silencing. Nature 394 (1998) 592-595
-
(1998)
Nature
, vol.394
, pp. 592-595
-
-
Andrulis, E.D.1
Neiman, A.M.2
Zappulla, D.C.3
Sternglanz, R.4
-
7
-
-
40749122641
-
Transcriptional repression mediated by repositioning of genes to the nuclear lamina
-
Reddy K.L., Zullo J.M., Bertolino E., and Singh H. Transcriptional repression mediated by repositioning of genes to the nuclear lamina. Nature 452 (2008) 243-247
-
(2008)
Nature
, vol.452
, pp. 243-247
-
-
Reddy, K.L.1
Zullo, J.M.2
Bertolino, E.3
Singh, H.4
-
8
-
-
41949121084
-
Recruitment to the nuclear periphery can alter expression of genes in human cells
-
Finlan L.E., Sproul D., Thomson I., Boyle S., Kerr E., Perry P., Ylstra B., Chubb J.R., and Bickmore W.A. Recruitment to the nuclear periphery can alter expression of genes in human cells. PLoS Genet 4 (2008) e1000039
-
(2008)
PLoS Genet
, vol.4
-
-
Finlan, L.E.1
Sproul, D.2
Thomson, I.3
Boyle, S.4
Kerr, E.5
Perry, P.6
Ylstra, B.7
Chubb, J.R.8
Bickmore, W.A.9
-
9
-
-
14044266853
-
Gene recruitment of the activated INO1 locus to the nuclear membrane
-
Brickner J.H., and Walter P. Gene recruitment of the activated INO1 locus to the nuclear membrane. PLoS Biol 2 (2004) e342
-
(2004)
PLoS Biol
, vol.2
-
-
Brickner, J.H.1
Walter, P.2
-
10
-
-
2342501365
-
Genome-wide localization of the nuclear transport machinery couples transcriptional status and nuclear organization
-
Casolari J.M., Brown C.R., Komili S., West J., Hieronymus H., and Silver P.A. Genome-wide localization of the nuclear transport machinery couples transcriptional status and nuclear organization. Cell 117 (2004) 427-439
-
(2004)
Cell
, vol.117
, pp. 427-439
-
-
Casolari, J.M.1
Brown, C.R.2
Komili, S.3
West, J.4
Hieronymus, H.5
Silver, P.A.6
-
11
-
-
34247341747
-
H2A.Z-mediated localization of genes at the nuclear periphery confers epigenetic memory of previous transcriptional state
-
This paper describes the discovery that INO1 and GAL1 remain at the nuclear periphery after repression and that this promotes more rapid reactivation. The authors also show that the histone variant H2A.Z is essential for both retention at the nuclear periphery and rapid reactivation.
-
Brickner D.G., Cajigas I.C., Fondufe-Mittendorf Y., Ahmed S., Lee P.-C., Widom J., and Brickner J.H. H2A.Z-mediated localization of genes at the nuclear periphery confers epigenetic memory of previous transcriptional state. PLoS Biol 5 (2007) e81. This paper describes the discovery that INO1 and GAL1 remain at the nuclear periphery after repression and that this promotes more rapid reactivation. The authors also show that the histone variant H2A.Z is essential for both retention at the nuclear periphery and rapid reactivation.
-
(2007)
PLoS Biol
, vol.5
-
-
Brickner, D.G.1
Cajigas, I.C.2
Fondufe-Mittendorf, Y.3
Ahmed, S.4
Lee, P.-C.5
Widom, J.6
Brickner, J.H.7
-
12
-
-
18844412748
-
Developmentally induced changes in transcriptional program alter spatial organization across chromosomes
-
Casolari J.M., Brown C.R., Drubin D.A., Rando O.J., and Silver P.A. Developmentally induced changes in transcriptional program alter spatial organization across chromosomes. Genes Dev 19 (2005) 1188-1198
-
(2005)
Genes Dev
, vol.19
, pp. 1188-1198
-
-
Casolari, J.M.1
Brown, C.R.2
Drubin, D.A.3
Rando, O.J.4
Silver, P.A.5
-
13
-
-
33744977019
-
Nuclear pore association confers optimal expression levels for an inducible yeast gene
-
Taddei A., Van Houwe G., Hediger F., Kalck V., Cubizolles F., Schober H., and Gasser S.M. Nuclear pore association confers optimal expression levels for an inducible yeast gene. Nature 441 (2006) 774-778
-
(2006)
Nature
, vol.441
, pp. 774-778
-
-
Taddei, A.1
Van Houwe, G.2
Hediger, F.3
Kalck, V.4
Cubizolles, F.5
Schober, H.6
Gasser, S.M.7
-
14
-
-
33750320374
-
Cotranscriptional recruitment to the mRNA export receptor Mex67p contributes to nuclear pore anchoring of activated genes
-
Dieppois G., Iglesias N., and Stutz F. Cotranscriptional recruitment to the mRNA export receptor Mex67p contributes to nuclear pore anchoring of activated genes. Mol Cell Biol 26 (2006) 7858-7870
-
(2006)
Mol Cell Biol
, vol.26
, pp. 7858-7870
-
-
Dieppois, G.1
Iglesias, N.2
Stutz, F.3
-
15
-
-
34249003318
-
Glucose-responsive regulators of gene expression in Saccharomyces cerevisiae function at the nuclear periphery via a reverse recruitment mechanism
-
Sarma N.J., Haley T.M., Barbara K.E., Buford T.D., Willis K.A., and Santangelo G.M. Glucose-responsive regulators of gene expression in Saccharomyces cerevisiae function at the nuclear periphery via a reverse recruitment mechanism. Genetics 175 (2007) 1127-1135
-
(2007)
Genetics
, vol.175
, pp. 1127-1135
-
-
Sarma, N.J.1
Haley, T.M.2
Barbara, K.E.3
Buford, T.D.4
Willis, K.A.5
Santangelo, G.M.6
-
16
-
-
31544471808
-
Nup-PI: the nucleopore-promoter interaction of genes in yeast
-
Schmid M., Arib G., Laemmli C., Nishikawa J., Durussel T., and Laemmli U.K. Nup-PI: the nucleopore-promoter interaction of genes in yeast. Mol Cell 21 (2006) 379-391
-
(2006)
Mol Cell
, vol.21
, pp. 379-391
-
-
Schmid, M.1
Arib, G.2
Laemmli, C.3
Nishikawa, J.4
Durussel, T.5
Laemmli, U.K.6
-
17
-
-
17644419993
-
Reverse recruitment: the Nup84 nuclear pore subcomplex mediates Rap1/Gcr1/Gcr2 transcriptional activation
-
Menon B.B., Sarma N.J., Pasula S., Deminoff S.J., Willis K.A., Barbara K.E., Andrews B., and Santangelo G.M. Reverse recruitment: the Nup84 nuclear pore subcomplex mediates Rap1/Gcr1/Gcr2 transcriptional activation. Proc Natl Acad Sci U S A 102 (2005) 5749-5754
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 5749-5754
-
-
Menon, B.B.1
Sarma, N.J.2
Pasula, S.3
Deminoff, S.J.4
Willis, K.A.5
Barbara, K.E.6
Andrews, B.7
Santangelo, G.M.8
-
18
-
-
60749104857
-
-
Manuscript under revision
-
Ahmed S, Brickner DG, McDonough M, Light WH, Volpe T, Brickner JH: DNA zip codes: an ancient mechanism for targeting genes to the nuclear periphery. Manuscript under revision.
-
DNA zip codes: An ancient mechanism for targeting genes to the nuclear periphery
-
-
Ahmed, S.1
Brickner, D.G.2
McDonough, M.3
Light, W.H.4
Volpe, T.5
Brickner, J.H.6
-
19
-
-
34047254106
-
Actively transcribed GAL genes can be physically linked to the nuclear pore by the SAGA chromatin modifying complex
-
Luthra R., Kerr S.C., Harreman M.T., Apponi L.H., Fasken M.B., Ramineni S., Chaurasia S., Valentini S.R., and Corbett A.H. Actively transcribed GAL genes can be physically linked to the nuclear pore by the SAGA chromatin modifying complex. J Biol Chem 282 (2007) 3042-3049
-
(2007)
J Biol Chem
, vol.282
, pp. 3042-3049
-
-
Luthra, R.1
Kerr, S.C.2
Harreman, M.T.3
Apponi, L.H.4
Fasken, M.B.5
Ramineni, S.6
Chaurasia, S.7
Valentini, S.R.8
Corbett, A.H.9
-
20
-
-
33745001795
-
SAGA interacting factors confine sub-diffusion of transcribed genes to the nuclear envelope
-
Cabal G.G., Genovesio A., Rodriguez-Navarro S., Zimmer C., Gadal O., Lesne A., Buc H., Feuerbach-Fournier F., Olivo-Marin J.C., Hurt E.C., et al. SAGA interacting factors confine sub-diffusion of transcribed genes to the nuclear envelope. Nature 441 (2006) 770-773
-
(2006)
Nature
, vol.441
, pp. 770-773
-
-
Cabal, G.G.1
Genovesio, A.2
Rodriguez-Navarro, S.3
Zimmer, C.4
Gadal, O.5
Lesne, A.6
Buc, H.7
Feuerbach-Fournier, F.8
Olivo-Marin, J.C.9
Hurt, E.C.10
-
21
-
-
34247279134
-
SWI/SNF is required for transcriptional memory at the yeast GAL gene cluster
-
This paper describes the discovery that GAL1, GAL2, GAL7 and GAL10 are more rapidly activated if they have previously been expressed. This transcriptional memory persists through cell division. Memory does not require histone acetylation or methylation but does require the SWI/SNF chromatin-remodeling complex. SWI/SNF functions to overcome ISW1/2-mediated repression.
-
Kundu S., Horn P.J., and Peterson C.L. SWI/SNF is required for transcriptional memory at the yeast GAL gene cluster. Genes Dev 21 (2007) 997-1004. This paper describes the discovery that GAL1, GAL2, GAL7 and GAL10 are more rapidly activated if they have previously been expressed. This transcriptional memory persists through cell division. Memory does not require histone acetylation or methylation but does require the SWI/SNF chromatin-remodeling complex. SWI/SNF functions to overcome ISW1/2-mediated repression.
-
(2007)
Genes Dev
, vol.21
, pp. 997-1004
-
-
Kundu, S.1
Horn, P.J.2
Peterson, C.L.3
-
22
-
-
33748933029
-
3′-end formation signals modulate the association of genes with the nuclear periphery as well as mRNP dot formation
-
Abruzzi K.C., Belostotsky D.A., Chekanova J.A., Dower K., and Rosbash M. 3′-end formation signals modulate the association of genes with the nuclear periphery as well as mRNP dot formation. EMBO J 25 (2006) 4253-4262
-
(2006)
EMBO J
, vol.25
, pp. 4253-4262
-
-
Abruzzi, K.C.1
Belostotsky, D.A.2
Chekanova, J.A.3
Dower, K.4
Rosbash, M.5
-
23
-
-
38049013812
-
Sus1, Sac3, and Thp1 mediate post-transcriptional tethering of active genes to the nuclear rim as well as to non-nascent mRNP
-
This paper shows that proteins involved in mRNA export are essential for the accumulation of mRNA 'dots' in association with GAL1 promoter-driven reporter genes and for their post-transcriptional localization at the nuclear periphery.
-
Chekanova J.A., Abruzzi K.C., Rosbash M., and Belostotsky D.A. Sus1, Sac3, and Thp1 mediate post-transcriptional tethering of active genes to the nuclear rim as well as to non-nascent mRNP. RNA 14 (2008) 66-77. This paper shows that proteins involved in mRNA export are essential for the accumulation of mRNA 'dots' in association with GAL1 promoter-driven reporter genes and for their post-transcriptional localization at the nuclear periphery.
-
(2008)
RNA
, vol.14
, pp. 66-77
-
-
Chekanova, J.A.1
Abruzzi, K.C.2
Rosbash, M.3
Belostotsky, D.A.4
-
24
-
-
46149085381
-
The nuclear exosome and adenylation regulate posttranscriptional tethering of yeast GAL genes to the nuclear periphery
-
Using both GAL1 promoter-driven reporter genes and the endogenous GAL1 gene, this paper argues that the nuclear exosome normally generates unpolyadenylated RNAs that accumulate in gene-associated 'dots'. These RNA dots and the associated reporter genes are localized at the nuclear periphery.
-
Vodala S., Abruzzi K.C., and Rosbash M. The nuclear exosome and adenylation regulate posttranscriptional tethering of yeast GAL genes to the nuclear periphery. Mol Cell 31 (2008) 104-113. Using both GAL1 promoter-driven reporter genes and the endogenous GAL1 gene, this paper argues that the nuclear exosome normally generates unpolyadenylated RNAs that accumulate in gene-associated 'dots'. These RNA dots and the associated reporter genes are localized at the nuclear periphery.
-
(2008)
Mol Cell
, vol.31
, pp. 104-113
-
-
Vodala, S.1
Abruzzi, K.C.2
Rosbash, M.3
-
25
-
-
53749089421
-
THO/Sub2p functions to coordinate 3′-end processing with gene-nuclear pore association
-
•] is associated with chromatin and interacts with the NPC. The accumulation of this intermediate and its targeting to the NPC requires the nuclear exosome.
-
•] is associated with chromatin and interacts with the NPC. The accumulation of this intermediate and its targeting to the NPC requires the nuclear exosome.
-
(2008)
Cell
, vol.135
, pp. 308-321
-
-
Rougemaille, M.1
Dieppois, G.2
Kisseleva-Romanova, E.3
Kanth Gudipati, R.4
Lemoine, S.5
Blugeon, C.6
Boulay, J.7
Heick Jensen, T.8
Stutz, F.9
Devaux, F.10
-
26
-
-
0038360922
-
Epigenetic gene regulation by noncoding RNAs
-
Andersen A.A., and Panning B. Epigenetic gene regulation by noncoding RNAs. Curr Opin Cell Biol 15 (2003) 281-289
-
(2003)
Curr Opin Cell Biol
, vol.15
, pp. 281-289
-
-
Andersen, A.A.1
Panning, B.2
-
27
-
-
0037636027
-
The establishment, inheritance, and function of silenced chromatin in Saccharomyces cerevisiae
-
Rusche L.N., Kirchmaier A.L., and Rine J. The establishment, inheritance, and function of silenced chromatin in Saccharomyces cerevisiae. Annu Rev Biochem 72 (2003) 481-516
-
(2003)
Annu Rev Biochem
, vol.72
, pp. 481-516
-
-
Rusche, L.N.1
Kirchmaier, A.L.2
Rine, J.3
-
28
-
-
1542285163
-
A concerted DNA methylation/histone methylation switch regulates rRNA gene dosage control and nucleolar dominance
-
Lawrence R.J., Earley K., Pontes O., Silva M., Chen Z.J., Neves N., Viegas W., and Pikaard C.S. A concerted DNA methylation/histone methylation switch regulates rRNA gene dosage control and nucleolar dominance. Mol Cell 13 (2004) 599-609
-
(2004)
Mol Cell
, vol.13
, pp. 599-609
-
-
Lawrence, R.J.1
Earley, K.2
Pontes, O.3
Silva, M.4
Chen, Z.J.5
Neves, N.6
Viegas, W.7
Pikaard, C.S.8
-
29
-
-
37249012276
-
Nucleosome destabilization in the epigenetic regulation of gene expression
-
Henikoff S. Nucleosome destabilization in the epigenetic regulation of gene expression. Nat Rev Genet 9 (2008) 15-26
-
(2008)
Nat Rev Genet
, vol.9
, pp. 15-26
-
-
Henikoff, S.1
-
30
-
-
0037423930
-
Conserved histone variant H2A.Z protects euchromatin from the ectopic spread of silent heterochromatin
-
Meneghini M.D., Wu M., and Madhani H.D. Conserved histone variant H2A.Z protects euchromatin from the ectopic spread of silent heterochromatin. Cell 112 (2003) 725-736
-
(2003)
Cell
, vol.112
, pp. 725-736
-
-
Meneghini, M.D.1
Wu, M.2
Madhani, H.D.3
-
31
-
-
26844511498
-
Histone variant H2A.Z marks the 5′ ends of both active and inactive genes in euchromatin
-
Raisner R.M., Hartley P.D., Meneghini M.D., Bao M.Z., Liu C.L., Schreiber S.L., Rando O.J., and Madhani H.D. Histone variant H2A.Z marks the 5′ ends of both active and inactive genes in euchromatin. Cell 123 (2005) 233-248
-
(2005)
Cell
, vol.123
, pp. 233-248
-
-
Raisner, R.M.1
Hartley, P.D.2
Meneghini, M.D.3
Bao, M.Z.4
Liu, C.L.5
Schreiber, S.L.6
Rando, O.J.7
Madhani, H.D.8
-
32
-
-
26844489856
-
Genome-wide dynamics of Htz1, a histone H2A variant that poises repressed/basal promoters for activation through histone loss
-
Zhang H., Roberts D.N., and Cairns B.R. Genome-wide dynamics of Htz1, a histone H2A variant that poises repressed/basal promoters for activation through histone loss. Cell 123 (2005) 219-231
-
(2005)
Cell
, vol.123
, pp. 219-231
-
-
Zhang, H.1
Roberts, D.N.2
Cairns, B.R.3
-
33
-
-
29144531244
-
Variant histone H2A.Z is globally localized to the promoters of inactive yeast genes and regulates nucleosome positioning
-
Guillemette B., Bataille A.R., Gevry N., Adam M., Blanchette M., Robert F., and Gaudreau L. Variant histone H2A.Z is globally localized to the promoters of inactive yeast genes and regulates nucleosome positioning. PLoS Biol 3 (2005) e384
-
(2005)
PLoS Biol
, vol.3
-
-
Guillemette, B.1
Bataille, A.R.2
Gevry, N.3
Adam, M.4
Blanchette, M.5
Robert, F.6
Gaudreau, L.7
-
34
-
-
34249026300
-
High-resolution profiling of histone methylations in the human genome
-
Barski A., Cuddapah S., Cui K., Roh T.Y., Schones D.E., Wang Z., Wei G., Chepelev I., and Zhao K. High-resolution profiling of histone methylations in the human genome. Cell 129 (2007) 823-837
-
(2007)
Cell
, vol.129
, pp. 823-837
-
-
Barski, A.1
Cuddapah, S.2
Cui, K.3
Roh, T.Y.4
Schones, D.E.5
Wang, Z.6
Wei, G.7
Chepelev, I.8
Zhao, K.9
-
35
-
-
43749099875
-
Nucleosome organization in the Drosophila genome
-
Mavrich T.N., Jiang C., Ioshikhes I.P., Li X., Venters B.J., Zanton S.J., Tomsho L.P., Qi J., Glaser R.L., Schuster S.C., et al. Nucleosome organization in the Drosophila genome. Nature 453 (2008) 358-362
-
(2008)
Nature
, vol.453
, pp. 358-362
-
-
Mavrich, T.N.1
Jiang, C.2
Ioshikhes, I.P.3
Li, X.4
Venters, B.J.5
Zanton, S.J.6
Tomsho, L.P.7
Qi, J.8
Glaser, R.L.9
Schuster, S.C.10
-
36
-
-
52949083577
-
The genomic distribution and function of histone variant HTZ-1 during C. elegans embryogenesis
-
Whittle C.M., McClinic K.N., Ercan S., Zhang X., Green R.D., Kelly W.G., and Lieb J.D. The genomic distribution and function of histone variant HTZ-1 during C. elegans embryogenesis. PLoS Genet 4 (2008) e1000187
-
(2008)
PLoS Genet
, vol.4
-
-
Whittle, C.M.1
McClinic, K.N.2
Ercan, S.3
Zhang, X.4
Green, R.D.5
Kelly, W.G.6
Lieb, J.D.7
-
37
-
-
0344022572
-
Targeted recruitment of Set1 histone methylase by elongating Pol II provides a localized mark and memory of recent transcriptional activity
-
Ng H.H., Robert F., Young R.A., and Struhl K. Targeted recruitment of Set1 histone methylase by elongating Pol II provides a localized mark and memory of recent transcriptional activity. Mol Cell 11 (2003) 709-719
-
(2003)
Mol Cell
, vol.11
, pp. 709-719
-
-
Ng, H.H.1
Robert, F.2
Young, R.A.3
Struhl, K.4
-
38
-
-
29144488127
-
The mobile nucleoporin Nup2p and chromatin-bound Prp20p function in endogenous NPC-mediated transcriptional control
-
Dilworth D.J., Tackett A.J., Rogers R.S., Yi E.C., Christmas R.H., Smith J.J., Siegel A.F., Chait B.T., Wozniak R.W., and Aitchison J.D. The mobile nucleoporin Nup2p and chromatin-bound Prp20p function in endogenous NPC-mediated transcriptional control. J Cell Biol 171 (2005) 955-965
-
(2005)
J Cell Biol
, vol.171
, pp. 955-965
-
-
Dilworth, D.J.1
Tackett, A.J.2
Rogers, R.S.3
Yi, E.C.4
Christmas, R.H.5
Smith, J.J.6
Siegel, A.F.7
Chait, B.T.8
Wozniak, R.W.9
Aitchison, J.D.10
-
39
-
-
0037205232
-
Chromatin boundaries in budding yeast: the nuclear pore connection
-
Ishii K., Arib G., Lin C., Van Houwe G., and Laemmli U.K. Chromatin boundaries in budding yeast: the nuclear pore connection. Cell 109 (2002) 551-562
-
(2002)
Cell
, vol.109
, pp. 551-562
-
-
Ishii, K.1
Arib, G.2
Lin, C.3
Van Houwe, G.4
Laemmli, U.K.5
-
40
-
-
34249337761
-
Perceptions of epigenetics
-
Bird A. Perceptions of epigenetics. Nature 447 (2007) 396-398
-
(2007)
Nature
, vol.447
, pp. 396-398
-
-
Bird, A.1
-
41
-
-
33947693747
-
On the use of the word 'epigenetic'
-
Ptashne M. On the use of the word 'epigenetic'. Curr Biol 17 (2007) R233-236
-
(2007)
Curr Biol
, vol.17
-
-
Ptashne, M.1
-
42
-
-
36549089092
-
A yeast catabolic enzyme controls transcriptional memory
-
Using heterokaryon analysis, the authors show that GAL gene transcriptional memory is conferred by a cytoplasmic factor. They identify the Gal1 protein as the cytoplasmic factor. Constitutive expression of Gal1 leads to more rapid transcriptional activation of GAL7, suggesting that this is sufficient to generate artificial memory.
-
Zacharioudakis I., Gligoris T., and Tzamarias D. A yeast catabolic enzyme controls transcriptional memory. Curr Biol 17 (2007) 2041-2046. Using heterokaryon analysis, the authors show that GAL gene transcriptional memory is conferred by a cytoplasmic factor. They identify the Gal1 protein as the cytoplasmic factor. Constitutive expression of Gal1 leads to more rapid transcriptional activation of GAL7, suggesting that this is sufficient to generate artificial memory.
-
(2007)
Curr Biol
, vol.17
, pp. 2041-2046
-
-
Zacharioudakis, I.1
Gligoris, T.2
Tzamarias, D.3
-
43
-
-
0037173045
-
Gene activation by interaction of an inhibitor with a cytoplasmic signaling protein
-
Peng G., and Hopper J.E. Gene activation by interaction of an inhibitor with a cytoplasmic signaling protein. Proc Natl Acad Sci U S A 99 (2002) 8548-8553
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 8548-8553
-
-
Peng, G.1
Hopper, J.E.2
-
44
-
-
37149020571
-
SAGA and a novel Drosophila export complex anchor efficient transcription and mRNA export to NPC
-
The hsp70 locus in Drosophila localizes at the nuclear periphery, in association with the nuclear pore complex (NPC). Full transcription and the localization at the nuclear periphery require the same NPC components that have been shown to function in gene recruitment to the nuclear periphery in yeast.
-
Kurshakova M.M., Krasnov A.N., Kopytova D.V., Shidlovskii Y.V., Nikolenko J.V., Nabirochkina E.N., Spehner D., Schultz P., Tora L., and Georgieva S.G. SAGA and a novel Drosophila export complex anchor efficient transcription and mRNA export to NPC. EMBO J 26 (2007) 4956-4965. The hsp70 locus in Drosophila localizes at the nuclear periphery, in association with the nuclear pore complex (NPC). Full transcription and the localization at the nuclear periphery require the same NPC components that have been shown to function in gene recruitment to the nuclear periphery in yeast.
-
(2007)
EMBO J
, vol.26
, pp. 4956-4965
-
-
Kurshakova, M.M.1
Krasnov, A.N.2
Kopytova, D.V.3
Shidlovskii, Y.V.4
Nikolenko, J.V.5
Nabirochkina, E.N.6
Spehner, D.7
Schultz, P.8
Tora, L.9
Georgieva, S.G.10
-
45
-
-
40349113413
-
Global histone acetylation induces functional genomic reorganization at mammalian nuclear pore complexes
-
In mammalian cells, certain genes associate with the NPC and relocalize from the nucleoplasm to the nuclear periphery upon treatment with histone deacetylase inhibitors. This suggests that peripheral targeting of active genes can also occur in mammalian cells.
-
Brown C.R., Kennedy C.J., Delmar V.A., Forbes D.J., and Silver P.A. Global histone acetylation induces functional genomic reorganization at mammalian nuclear pore complexes. Genes Dev 22 (2008) 627-639. In mammalian cells, certain genes associate with the NPC and relocalize from the nucleoplasm to the nuclear periphery upon treatment with histone deacetylase inhibitors. This suggests that peripheral targeting of active genes can also occur in mammalian cells.
-
(2008)
Genes Dev
, vol.22
, pp. 627-639
-
-
Brown, C.R.1
Kennedy, C.J.2
Delmar, V.A.3
Forbes, D.J.4
Silver, P.A.5
|