Cerebral Protection by Lidocaine During Cardiac Operations: A Follow-Up Study

Annals of Thoracic Surgery

Volumn 87, Issue 3, 2009, Pages 820-825

  Mitchell, Simon J ^a,c   Merry, Alan F ^a,c   Frampton, Christopher ^b   Davies, Elaine ^a   Grieve, Diana ^a   Mills, Brigid P ^a   Webster, Craig S ^a   Milsom, F Paget ^c   Willcox, Timothy W ^c   Gorman, Desmond F ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b StatistEcol   (New Zealand)

^c AUCKLAND CITY HOSPITAL   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

LIDOCAINE; PLACEBO;

ADULT; AGED; ANXIETY; ARTICLE; CLINICAL TRIAL; COGNITIVE DEFECT; CONTINUOUS INFUSION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY BYPASS SURGERY; DEPRESSION; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; FEMALE; FOLLOW UP; HOSPITALIZATION; HUMAN; INTENSIVE CARE UNIT; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MEMORY; NEUROPROTECTION; NEUROPSYCHOLOGICAL TEST; POSTOPERATIVE COMPLICATION; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; SELF EVALUATION; TREATMENT DURATION;

BRAIN DISEASES; CARDIAC SURGICAL PROCEDURES; COGNITION DISORDERS; DOUBLE-BLIND METHOD; FEMALE; FOLLOW-UP STUDIES; HUMANS; LIDOCAINE; MALE; MIDDLE AGED; TIME FACTORS;

EID: 60749085408     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.athoracsur.2008.12.042     Document Type: Article

References (22)

1. Hogue C.W., Palin C.A., and Arrowsmith J.E. Cardiopulmonary bypass management and neurologic outcomes: an evidence based appraisal of current practices. Anesth Analg 103 (2006) 21-37
2. Newman M.F., Kirchner J.L., Phillips-Bute, et al. Longitudinal assessment of neurocognitive function after coronary-artery bypass surgery. N Engl J Med 344 (2001) 395-402
3. Shann K.G., Likosky D.S., Murkin J.M., et al. An evidence based review of the practice of cardiopulmonary bypass in adults: a focus on neurological injury, glycemic control, hemodilution, and the inflammatory response. J Thorac Cardiovasc Surg 132 (2006) 283-290
4. Mitchell S.J. Lidocaine in the treatment of decompression illness: a review of the literature. Undersea Hyperbaric Med 28 (2001) 165-174
5. Mitchell S.J., Pellett O., and Gorman D.F. Cerebral protection by lidocaine during cardiac operations. Ann Thorac Surg 67 (1999) 1117-1124
6. Wang D., Wu X., Li J., Xiao F., Liu X., and Meng M. The effect of lidocaine on early postoperative cognitive dysfunction after coronary artery bypass surgery. Anesth Analg 95 (2002) 1134-1141
7. Lezak M.D. Neuropsychological Assessment. 3rd ed. (1995), Oxford University Press, Oxford, UK
8. Murkin J.M., Newman S.P., Stump D.A., and Blumenthal J.A. Statement of consensus on assessment of neurobehavioural outcomes after cardiac surgery. Ann Thorac Surg 59 (1995) 1289-1295
9. Crook T.H., and Larrabee G.J. S self-rating scale for evaluating memory in everyday life. Psychology Aging 5 (1990) 48-57
10. Zigmond A.S., and Snaith R.P. The Hospital Anxiety and Depression Scale. Acta Psychiatr Scand 67 (1983) 361-370
11. Bright P., Jaldow E., and Kopelman M.D. The National Adult Reading Test as a measure of premorbid intelligence: a comparison with estimates derived from demographic variables. J Int Neuropsych Soc 8 (2002) 847-854
12. Evans D.E., Kobrine A.I., LeGrys D.C., and Bradley M.E. Protective effect of lidocaine in acute cerebral ischaemia induced by air embolism. J Neurosurg 60 (1984) 257-263
13. Lei B., Cottrell J.E., and Kass I.S. Neuroprotective effect of low-dose lidocaine in a rat model of transient focal ischemia. Anesthesiology 95 (2001) 445-451
14. Lei B., Popp S., Capuano-Waters C., Cottrell J.E., and Kass I.S. Lidocaine attenuates apoptosis in the ischemic penumbra and reduces infarct size after transient focal cerebral ischemia in rats. Neuroscience 125 (2004) 691-701
15. Niiyama S., Tanaka E., Tsuji S., et al. Neuroprotective mechanisms of lidocaine against in vitro ischemic insult of the rat hippocampal CA1 pyramidal neurons. Neurosci Res 53 (2005) 271-278
16. Urenjak J., and Obrenovitch T.P. Pharmacological modulation of voltage-gated Na+ channels: a rational and effective strategy against ischemic brain damage. Pharmacol Rev 48 (1996) 21-67
17. Sakabe T., Maekawa T., Ishikawa T., and Takeshita H. The effects of lidocaine on canine cerebral metabolism and circulation related to the EEG. Anesthesiology 40 (1974) 433-441
18. MacGregor R.R., Thorner R.E., and Wright D.M. Lidocaine inhibits granulocyte adherence and prevents granulocyte delivery to inflammatory sites. Blood 56 (1980) 203-209
19. Drewry A., and Gorman D.F. Lidocaine as an adjunct to hyperbaric therapy in decompression illness: a case report. Undersea Biomed Res 19 (1992) 187-190
20. Stump D.A., Stein C.S., Tegeler C.H., et al. Validity and reliability of an ultrasound device for detecting carotid emboli. J Neuroimag 1 (1991) 18-22
21. Nussmeier N.A. Adverse neurological events: risks of intracardiac versus extracardiac surgery. J Cardiothorac Vasc Anesth 10 (1996) 31-37
22. Mathew J.P., Grocott H.P., Phillips-Bute B., and Newman M.F. Lidocaine does not prevent cognitive dysfunction after cardiac surgery. http://outcomeskeywest.com/Portals/16/Abstracts/2004/3-6.pdf Accessed July 18, 2008