Retrospective evaluation of amphotericin B deoxycholate toxicity in a single centre series of haematopoietic stem cell transplantation recipients

Journal of Antimicrobial Chemotherapy

Volumn 63, Issue 3, 2009, Pages 625-626

  Annaloro, Claudio ^a   Olivares, Cecilia ^a,b   Usardi, Patrizia ^a   Onida, Francesco ^a,b   Della Volpe, Aldo ^a   Tagliaferri, Elena ^a   Deliliers, Giorgio Lambertenghi ^a,b  

^a FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

Ampirical antifungal therapy; D AMB; HSCT

Indexed keywords

AMIKACIN; AMPHOTERICIN B DEOXYCHOLATE; ANTIHISTAMINIC AGENT; POTASSIUM; POTASSIUM CHLORIDE; SODIUM CHLORIDE;

ACUTE KIDNEY FAILURE; ADOLESCENT; ADULT; AGED; ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CREATININE CLEARANCE; DRUG INDUCED DISEASE; FEMALE; GRAFT RECIPIENT; HUMAN; HYDRATION; HYPOKALEMIA; LETTER; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; NEPHROTOXICITY; POTASSIUM BLOOD LEVEL; RETROSPECTIVE STUDY; SIDE EFFECT; SINGLE DRUG DOSE; TREATMENT DURATION;

ADOLESCENT; ADULT; AGED; AMPHOTERICIN B; ANTIFUNGAL AGENTS; DEOXYCHOLIC ACID; DRUG COMBINATIONS; FEMALE; HUMANS; MALE; MIDDLE AGED; MYCOSES; RETROSPECTIVE STUDIES; STEM CELL TRANSPLANTATION; YOUNG ADULT;

EID: 60649117559     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkn549     Document Type: Letter

References (6)

1. Bates DW, Su L, Yu DT et al. Mortality and costs of acute renal failure associated with amphotericin B therapy. Clin Infect Dis 2001; 32: 686-93.
2. Cagnoni PJ, Walsh TJ, Prendergast MM et al. Pharmacoeconomic analysis of liposomal amphotericin B versus conventional amphotericin B in the empirical treatment of persistently febrile neutropenic patients. Clin Oncol 2000; 18: 2476-83.
3. Girmenia C, Cimino G, Di Cristofano F et al. Effects of hydration with salt repletion on renal toxicity of conventional amphotericin B empirical therapy: A prospective study in patients with hematological malignancies. Support Care Cancer 2005; 13: 987-92.
4. Oto OA, Paydas S, Disel U et al. Amphotericin B deoxycholate (d-AMB) use in cases with febrile neutropenia and fungal infections: lower toxicity with suitable premedication. Mycoses 2007; 50 135-9.
5. Imhof A, Walter RB, Schaffner A. Continuous infusion of escalated doses of amphotericin B deoxycholate: An open-label observational study. Clin Infect Dis 2003; 36: 943-51.
6. Schulenburg A, Sperr W, Rabitsch W et al. Brief report: practicability and safety of amphotericin B deoxycholate as continuous infusion in neutropenic patients with hematological malignancies. Leuk Lymphoma 2005; 46: 1163-7.