Comparison of Lung and Kidney Allografts in Induction of Tolerance by a Mixed-Chimerism Approach in Cynomolgus Monkeys

Transplantation Proceedings

Volumn 41, Issue 1, 2009, Pages 429-430

  Aoyama, A ^a   Ng, C Y ^a   Millington, T M ^a   Boskovic, S ^a   Murakami, T ^a   Wain, J C ^a   Houser, S L ^a   Madsen, J C ^a   Kawai, T ^a   Allan, J S ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN; CD40 LIGAND MONOCLONAL ANTIBODY; CYCLOSPORIN; OKT 8; THYMOCYTE ANTIBODY;

ALLOGRAFT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASE MISPAIRING; BONE MARROW TRANSPLANTATION; CHIMERA; CONTROLLED STUDY; IMMUNOLOGICAL TOLERANCE; KIDNEY TRANSPLANTATION; LUNG GRAFT REJECTION; LUNG TRANSPLANTATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; MALE; MONKEY; MYELOABLATIVE CONDITIONING; NONHUMAN; PRIORITY JOURNAL; SURVIVAL TIME; THYMUS; WHOLE BODY RADIATION;

ABO BLOOD-GROUP SYSTEM; ANIMALS; ANTILYMPHOCYTE SERUM; BONE MARROW TRANSPLANTATION; GRAFT SURVIVAL; HISTOCOMPATIBILITY TESTING; IMMUNE TOLERANCE; KIDNEY TRANSPLANTATION; LUNG TRANSPLANTATION; MACACA FASCICULARIS; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; TRANSPLANTATION CHIMERA; WHOLE-BODY IRRADIATION;

EID: 60649113440     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2008.08.147     Document Type: Article

References (6)

1. Trulock E.P., Edwards L.B., Taylor D.O., et al. Registry of the International Society for Heart and Lung Transplantation: twenty-third official adult lung and heart-lung transplantation report-2006. J Heart Lung Transplant 25 (2006) 880
2. Sharabi Y., and Sachs D.H. Mixed chimerism and permanent specific transplantation tolerance induced by a nonlethal preparative regimen. J Exp Med 169 (1989) 493
3. Tomita Y., Khan A., and Sykes M. Role of intrathymic clonal deletion and peripheral anergy in transplantation tolerance induced by bone marrow transplantation in mice conditioned with a nonmyeloablative regimen. J Immunol 153 (1994) 1087
4. Kawai T., Cosimi A.B., Colvin R.B., et al. Mixed allogeneic chimerism and renal allograft tolerance in cynomolgus monkeys. Transplantation 59 (1995) 256-262
5. Kawai T., Sogawa H., Boskovic S., et al. CD154 blockade for induction of mixed chimerism and prolonged renal allograft survival in nonhuman primates. Am J Transplant 4 (2004) 1391
6. Kawai T., Cosimi A.B., Spitzer T.R., et al. HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med 358 (2008) 353