Pharmacokinetics of linezolid in human non-inflamed vitreous after systemic administration

Journal of Antimicrobial Chemotherapy

Volumn 63, Issue 3, 2009, Pages 550-552

  Horcajada, Juan P ^a   Atienza, Rebeka ^a   Sarasa, María ^a   Soy, Dolors ^a   Adán, Alfredo ^a   Mensa, Josep ^a  

^a HOSPITAL CLÍNIC   (Spain)

Author keywords

Eye; Oxazolidinones; Penetration

Indexed keywords

LINEZOLID;

ABSENCE OF SIDE EFFECTS; ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIABETIC RETINOPATHY; DRUG BLOOD LEVEL; DRUG TISSUE LEVEL; ENDOPHTHALMITIS; FEMALE; HUMAN; LENS SUBLUXATION; MALE; MAXIMUM PLASMA CONCENTRATION; MINIMUM INHIBITORY CONCENTRATION; RETINA DETACHMENT; RETINA MACULA HOLE; STAPHYLOCOCCUS EPIDERMIDIS; VITRECTOMY;

ACETAMIDES; ADULT; AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; FEMALE; HUMANS; INFUSIONS, INTRAVENOUS; MALE; MIDDLE AGED; OXAZOLIDINONES; SERUM; TIME FACTORS; VITREOUS BODY;

EID: 60649105776     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkn516     Document Type: Article

References (17)

1. Kattan HM, Flynn HW Jr, Pflugfelder SC et al. Nosocomial endophthalmitis survey. Current incidence of infection after intraocular surgery. Ophthalmology 1991; 98: 227-38.
2. Ng JQ, Morlet N, Pearman JW et al. Management and outcomes of postoperative endophthalmitis since the Endophthalmitis Vitrectomy Study: The Endophthalmitis Population Study of Western Australia (EPSWA)'s fifth report. Ophthalmology 2005; 112: 1199-206.
3. Endophthalmitis Vitrectomy Study Group. Results of the Endophthalmitis Vitrectomy Study. A randomized trial of immediate vitrectomy and of intravenous antibiotics for the treatment of postoperative bacterial endophthalmitis. Arch Ophthalmol 1995; 113: 1479-96.
4. Kunimoto DY, Das T, Sharma S et al. Microbiologic spectrum and susceptibility of isolates: Part I. Postoperative endophthalmitis. Am J Ophthalmol 1999; 128: 240-2.
5. Al-Omran AM, Abboud EB, Abu El-Asrar AM. Microbiologic spectrum and visual outcome of posttraumatic endophthalmitis. Retina 2007; 27: 236-42.
6. Axelrod JL, Klein RM, Bergen RL et al. Human vitreous levels of selected antistaphylococcal antibiotics. Am J Ophthalmol 1985; 100: 570-5.
7. Fiscella RG, Nguyen TKP, Cwik MJ et al. Aqueous and vitreous penetration of levofloxacin after oral administration. Ophthalmology 1999; 106: 2286-90.
8. Hariprasad SM, Shah GK, Mieler WF et al. Vitreous and aqueous penetration of orally administered moxifloxacin in humans. Arch Ophthalmol 2006; 124: 178-82.
9. Herbert EN, Pearce IA, McGalliard J et al. Vitreous penetration of levofloxacin in the uninflamed phakic human eye. Br J Ophthalmol 2002; 86: 387-9.
10. Vedantham V, Lalitha P, Velpandian T et al. Vitreous and aqueous penetration of orally administered moxifloxacin in humans. Eye 2006; 20: 1273-8.
11. Jones R, Ballow C, Bidenbach D. Multi-laboratory assessment of the linezolid spectrum of activity using the Kirby-Bauer disk diffusion method. Report of the Zyvox Antimicrobial Potency Study (ZAPS) in the United States. Diagn Microbiol Infect Dis 2001; 40: 59-66.
12. Vázquez EG, Mensa J, López Y et al. Penetration of linezolid into the anterior chamber (aqueous humour) of the human eye after intravenous administration. Antimicrob Agents Chemother 2004; 48: 670-2.
13. Ciulla TA, Comer GM, Peloquin C et al. Human vitreous distribution of linezolid after a single oral dose. Retina 2005; 25: 619-24.
14. Fiscella RG, Lai WW, Buerk B et al. Aqueous and vitreous penetration of linezolid (Zyvox) after oral administration. Ophthalmology 2004; 111: 1191-5.
15. Soriano F, Pérez-Trallero E, Pallarés R et al. Streptococcus pneumoniae endophthalmitis: A study of 36 cases with special reference to antibiotic resistance and treatment options. Clin Microbiol Infect 2006; 12: 519-26.
16. Speaker MG, Milch FA, Shah MK et al. Role of external bacterial flora in the pathogenesis of acute postoperative endophthalmitis. Ophthalmology 1991; 98: 639-50.
17. Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing: Sixteenth Informational Supplement M100-S16. CLSI, Wayne, PA, USA, 2006.