Interaction of angiotensin-converting enzyme and apolipoprotein E gene polymorphisms in ischemic stroke involving large-vessel disease

Journal of Thrombosis and Thrombolysis

Volumn 27, Issue 1, 2009, Pages 68-74

  Saidi, Sarra ^a   Zammiti, Walid ^a   Slamia, Lamia B ^b   Ammou, Sofyan B ^b   Almawi, Wassim Y ^a,c   Mahjoub, Touhami ^a  

^a UNIVERSITY OF MONASTIR   (Tunisia)

^b SAHLOUL UNIVERSITY HOSPITAL   (Tunisia)

^c ARABIAN GULF UNIVERSITY   (Bahrain)

Author keywords

ACE; Apolipoprotein E; Cholesterol; Gene polymorphism; Stroke

Indexed keywords

APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; CHOLESTEROL; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HIGH DENSITY LIPOPROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LIPID; LOW DENSITY LIPOPROTEIN; TRIACYLGLYCEROL;

ADULT; ARTICLE; BRAIN BLOOD VESSEL; CEREBROVASCULAR ACCIDENT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DNA POLYMORPHISM; DYSLIPIDEMIA; FEMALE; GENE DELETION; GENE FREQUENCY; GENE INSERTION; GENE INTERACTION; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HUMAN; HYPERTENSION; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PREVALENCE; PRIORITY JOURNAL; TUNISIA;

AGE FACTORS; AGED; ALLELES; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; BRAIN ISCHEMIA; CASE-CONTROL STUDIES; COMORBIDITY; EPIGENESIS, GENETIC; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; INTRACRANIAL ARTERIOSCLEROSIS; LIPIDS; MALE; MIDDLE AGED; PEPTIDYL-DIPEPTIDASE A; POLYMORPHISM, GENETIC; RISK FACTORS; SEQUENCE DELETION; TUNISIA;

EID: 60649092986     PISSN: 09295305     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11239-007-0165-y     Document Type: Article

References (35)

1. Gao X, Yang H, ZhiPing T (2006) Association studies of genetic polymorphism, environmental factors and their interaction in ischemic stroke. Neurosci Lett 398:172-177
2. Hassan A, Markus HS (2000) Genetics and ischemic stroke. Brain 123:1784-1812
3. Ariyaratnam R, Casas JP, Whittaker J et al (2007) Genetics of ischaemic stroke among persons of non-European descent: A meta-analysis of eight genes involving approximately 32,500 individuals. PLoS Med 4:e131
4. Banerjee I, Gupta V, Ganesh S (2007) Association of gene polymorphism with genetic susceptibility to stroke in Asian populations: A meta-analysis. J Hum Genet 52:205-219
5. Liao D, Myers R, Hunt S et al (1997) Familial history of stroke and stroke risk: The Family Heart Study. Stroke 28:1908-1912
6. Um JY, Kim HM, Park HS et al (2005) Candidate genes of cerebral infarction and traditional classification in Koreans with cerebral infarction. Int J Neurosci 115:743-756
7. Zhang JH, Kohara K, Yamamoto Y et al (2004) Genetic predisposition to neurological symptoms in lacunar infarction. Cerebrovasc Dis 17:273-279
8. Nakata Y, Katsuya T, Rakugi H et al (1997) Polymorphism of angiotensin converting enzyme, angiotensinogen, and apolipoprotein E genes in a Japanese population with cerebrovascular disease. Am J Hypertens 10:1391-1395
9. Slowik A, Turaj W, Dziedzic T et al (2004) DD genotype of ACE gene is a risk factor for intracerebral hemorrhage. Neurology 63:359-361
10. Um JY, Moon KS, Lee KM et al (2003) Polymorphism of angiotensin-converting enzyme, angiotensinogen, and apolipoprotein E genes in Korean patients with cerebral infarction. J Mol Neurosci 21:23-28
11. Szolnoki Z (2005) Evaluation of the interactions of common genetic mutations in stroke. Methods Mol Med 104:241-250
12. Siest G, Pillot T, Regis-Bailly A et al (1995) Apolipoprotein E: An important gene and protein to follow in laboratory medicine. Clin Chem 41:1068-1086
13. Batalla A, Alvarez R, Reguero JR et al (2000) Synergistic effect between apolipoprotein E and angiotensinogen gene polymorphisms in the risk for early myocardial infarction. Clin Chem 46:1910-1915
14. Luc G, Bard J, Arveiler D (1994) Impact of apolipoprotein E polymorphism on lipoproteins and risk of myocardial infarction: The ECTIM study. Arterioscler Thromb 14:1412-1419
15. Karagiannis A, Balaska K, Tziomalos K et al (2004) Lack of an association between angiotensin-converting enzyme gene insertion/ deletion polymorphism and ischaemic stroke. Eur Neurol 51:148-152
16. Tuncer N, Tuglular S, Kilic G et al (2006) Evaluation of the angiotensin-converting enzyme insertion/deletion polymorphism and the risk of ischaemic stroke. J Clin Neurosci 13:224-227
17. O'Malley JP, Maslen CL, Illingworth DR (1998) Angiotensin-converting enzyme DD genotype and cardiovascular disease in heterozygous familial hypercholesterolemia. Circulation 97:1780-1783
18. Nickenig G, Jung O, Strehlow K et al (1997) Hypercholesterolemia is associated with enhanced angiotensin AT1-receptor expression. Am J Physiol 272:H2701-H2707
19. Schmieder RE, Hilgers KF, Schlaich MP, Schmidt BM (2007) Renin-angiotensin system and cardiovascular risk. Lancet 369:1208-1219
20. Keidar S, Attias J, Heinrich R et al (1999) Angiotensin II atherogenicity in apolipoprotein E deficient mice is associated with increased cellular cholesterol biosynthesis. Atherosclerosis 146:249-257
21. Bosse Y, Vohl MC, Dumont M et al (2002) Influence of the angiotensin-converting enzyme gene insertion/deletion polymorphism on lipoprotein/lipid response to gemfibrozil. Clin Genet 62:45-52
22. Ruland S, Gorelick PB (2003) Are cholesterol-lowering medications and anti-hypertensive agents preventing stroke in ways other than by controlling the risk factor? Curr Atheroscler Rep 5:38-43
23. Rigat B, Hubert C, Corvol P, Soubrier F (1992) PCR detection of the insertion/deletion polymorphism of the human angiotensin-converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1). Nucleic Acids Res 20:1433
24. Al-Khedhairy AA (2004) Apolipoprotein E polymorphism in Saudis. Mol Biol Rep 31: 257-260
25. Mahfouz RA, Sabbagh AS, Zahed LF et al (2006) Apolipoprotein E gene polymorphism and allele frequencies in the Lebanese population. Mol Biol Rep 33:145-149
26. Al-Bustan SA, Alnaqeeb MA, Annice BG et al (2005) Apolipoprotein E genotyping among the healthy Kuwaiti population. Hum Biol 77:487-498
27. Lahlali-Kacemi N, Bamou Y, Guedira A et al (2002) Polymorphisme de l'apolipoprotéine E dans une population marocaine: fréquence allélique et relation avec les paramètres lipidiques plasmatiques. Ann Biol Clin 60:73-78
28. Tikkanen MJ, Huttunen JK, Ehnholm C, Pietinen P (1990) Apolipoprotein E4 homozygosity predisposes to serum cholesterol elevation during high fat diet. Arteriosclerosis 10:285-288
29. Rigat B, Hubert C, Alhenc-Gelas F et al (1990) An insertion: deletion polymorphism in the angiotensin 1-converting enzyme gene accounting for half of the variance of serum enzyme levels. J Clin Invest 86:1343-1346
30. Pera J, Slowik A, Dziedzic T et al (2006) ACE I/D polymorphism in different etiologies of ischemic stroke. Acta Neurol Scand 114:320-322
31. Bennouar N, Allami A, Laraqui A et al (2004) Apolipoprotein E and angiotensin-converting enzyme gene polymorphisms as risk factors of coronary disease. Ann Biol Clin (Paris) 62:295-304
32. Catto A, Carter AM, Barrett JH et al (1996) Angiotensin-converting enzyme insertion/deletion polymorphism and cerebrovascular disease. Stroke 27:435-440
33. Hachinski V, Graffagnino C, Beaudry M et al (1996) Lipids and stroke: A paradox resolved. Arch Neurol 53:303-308
34. del Ser T, Bornstein B, Barba R et al (2001) Relationship of angiotensin converting enzyme genotype with serum triglyceride concentration in stroke patients. Neurosci Lett 316:21-24
35. Okura Y, Hayashi K, Shingu T et al (2003) Angiotensin-converting enzyme insertion/deletion genotype is associated with the activities of plasma coagulation factor VII and X independent of triglyceride metabolism. Coron Artery Dis 14:285-291