Simulation and modeling of optical phase contrast microscope cellular nanobioimaging

Proceedings of SPIE - The International Society for Optical Engineering

Volumn 7027, Issue , 2008, Pages

  Tanev, Stoyan ^a   Tuchin, Valery V ^b,c   Pond, James ^d  

^a CARLETON UNIVERSITY   (Canada)

^b SARATOV STATE UNIVERSITY   (Russian Federation)

^c INSTITUTE OF PRECISION MECHANICS AND CONTROL   (Russian Federation)

^d Lumerical Solutions Inc   (Canada)

Author keywords

Biological cell; Finite difference time domain method; Gold NPs; Optical clearing effect; Optical phase contrast microscope

Indexed keywords

CYTOLOGY; ELECTRON OPTICS; FINITE DIFFERENCE TIME DOMAIN METHOD; GOLD; IMAGE RESOLUTION; METHOD OF MOMENTS; MICROSCOPES; QUANTUM ELECTRONICS; REFRACTIVE INDEX; SYSTEMS ENGINEERING; VISUAL COMMUNICATION;

AT RESONANCES; BIOLOGICAL CELL; CELL MODELS; FINITE-DIFFERENCE TIME-DOMAIN SIMULATIONS; GOLD NANOPARTICLES; GOLD NPS; NON-RESONANT; OPTICAL CLEARING EFFECT; OPTICAL IMMERSIONS; OPTICAL PHASE CONTRAST MICROSCOPE; SIMULATION AND MODELING; VISUAL EFFECTS; VISUAL PATTERNS;

THREE DIMENSIONAL;

EID: 60649092709     PISSN: 0277786X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.822518     Document Type: Conference Paper

References (20)

1. Prasad, P. N., [Introduction to Biophotonics], Ch. 7, John Wiley & Sons, New Jersey, (2003). Tuchin, V. V., [Tissue Optics: Light Scattering Methods and Instruments for Medical Diagnosis], SPIE Press Monograph, Vol. PM 166, Second edition, SPIE Publications, Bellingham, (2007).
2. Kahnert, F. M., "Numerical methods in electromagnetic scattering theory," Journal of Quantitative Spectroscopy and Radiative Transfer 73, 775-824 (2003).
3. Drezek, R., Dunn, A. and Richards-Kortum, R., "A pulsed finite-difference time-domain (FDTD) method for calculating light scattering from biological cells over broad wavelength ranges," Optics Express 6, 147-157 (2000).
4. Tanifuji, T. and Hijikata, M., "Finite difference time domain (FDTD) analysis of optical pulse responses in biological tissues for spectroscopic diffused optical tomography," IEEE Transactions on Medical Imaging 21, 181-184 (2002).
5. Drezek, R., Guillaud, M., Collier, T., Boiko, I., Malpica, A., Macaulay, C., Follen, M. and Richards-Kortum, R., "Light scattering from cervical cells throughout neoplastic progression: influence of nuclear morphology, DNA content, and chromatin texture," Journal of Biomedical Optics 8, 7-16 (2003).
6. Tanev, S., Tuchin, V. V. and Paddon, P., "Light scattering effects of gold nanoparticles in cells," Laser Physics Letters 3(12), 594-598 (2006).
7. Tanev, S., Tuchin, V. V. and Paddon, P., "Cell membrane and gold nanoparticles effects on optical immersion experiments with noncancerous and cancerous cells: finite-difference time-domain modeling", Journal of Biomedical Optics 11(6), 064037-1-6 (2006).
8. Tanev, S., Pond, J., Paddon, P. and Tuchin, V. V., "FDTD simulation of optical phase contrast microscope imaging," Proc. SPIE 6991, 66912D-1-9 (2008).
9. Li, X., Taflove, A. and Backman, V., "Recent progress in exact and reduced-order modeling of light-scattering properties of complex structures," IEEE J. Selected Topics in Quantum Electronics 11, 759-765 (2005).
10. Barer, R., Ross, K. F. A. and Tkaczyk, S., "Refractometry of living cells," Nature 171, 720-724 (1953).
11. Fikhman, B. A., [Microbiological Refractometry], Medicine, Moscow, (1967).
12. Tuchin, V.V., [Optical Clearing of Tissues and Blood], SPIE Press Publications, Vol. PM 154, (2005).
13. Taflove, A. and Hagness, S., [Computational Electrodynamics: The Finite-Difference Time Domain Method], 3rd edition, Artech House Publishers, Boston (2005).
14. The simulations were performed by the FDTD Solutions™ software developed by Lumerical Solutions Inc., Vancouver, BC, Canada: www.lumerical.com
15. Sokolov, K., Follen, M., Aaron, J., Pavlova, I., Malpica, A., Lotan, R. and Richards-Kortum, R., "Real-time vital optical imaging of precancer using anti-epidermal growth factor receptor antibodies conjugated to gold nanoparticles," Cancer Research 63, 1999-2004 (2003).
16. El-Sayed, I. H., Huang, X. and El-Sayed, M. A., "Surface plasmon resonance scattering and absorption of anti-EGFR antibody conjugated gold nanoparticles in cancer diagnostics: applications in oral cancer," Nano Letters 5(5), 829- 834 (2005).
17. Khlebtsov, N. G., Melnikov, A. G., Dykman, L. A. and Bogatyrev, V. A. "Optical properties and biomedical applications of nanostructures based on gold and silver bioconjugates," in [Photopolarimetry in Remote Sensing], Videen, G., Yatskiv, Ya. S. and Mishchenko, M. I., Editors, NATO Science Series, II. Mathematics, Physics and Chemistry, Vol. 161, Kluwer, Dordrecht, 265-308 (2004).
18. Zharov, V. P., Kim, J.-W., Curiel, D. T. and Everts, M., "Self-assembling nanoclusters in living systems: application for integrated photothermal nanodiagnostics and nanotherapy," Nanomedicine: Nanotechnology, Biology, and Medicine 1, 326-345 (2005).
19. Zharov, V. P., Mercery, K. E., Galitovskaya, E. N. and Smeltzer, M. S., "Photothermal nano therapeutics and nanodiagnostics for selective killing of bacteria targeted with gold nanoparticles," Biophysical Journal 90, 619-627 (2006).
20. Johnson, P. B. and Christy, R. W., "Optical constants of the noble metals," Physical Review B 6, 4370-4379 (1972).