Effect of Megestrol Acetate on Serum Albumin Level in Malnourished Dialysis Patients

Journal of Renal Nutrition

Volumn 19, Issue 2, 2009, Pages 167-171

  Monfared, Ali ^a   Heidarzadeh, Abtin ^a   Ghaffari, Maryam ^a   Akbarpour, Marzieh ^a  

^a GUILAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

APPETITE STIMULANT; BIOLOGICAL MARKER; MEGESTROL ACETATE; SERUM ALBUMIN;

ARTICLE; BLOOD; CHRONIC KIDNEY FAILURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HUMAN; MALE; MALNUTRITION; METABOLISM; MIDDLE AGED; NUTRITIONAL STATUS; RANDOMIZED CONTROLLED TRIAL; RENAL REPLACEMENT THERAPY; TREATMENT OUTCOME;

APPETITE STIMULANTS; BIOLOGICAL MARKERS; FEMALE; HUMANS; KIDNEY FAILURE, CHRONIC; MALE; MALNUTRITION; MEGESTROL ACETATE; MIDDLE AGED; NUTRITIONAL STATUS; RENAL DIALYSIS; SERUM ALBUMIN; TREATMENT OUTCOME;

EID: 60649091540     PISSN: 10512276     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.jrn.2008.11.003     Document Type: Article

References (16)

1. Kalantar-Zadeh K., Block G.J., McAllister C., et al. Appetite and inflammation, nutrition, anemia, and clinical outcome in hemodialysis patients. Am J Clin Nutr 80 (2004) 299-307
2. Morley E.J., Thomas R.D., Mary G., and Wilson M. Cachexia: pathophysiology and clinical relevance. Am J Clin Nutr 83 (2006) 735-743
3. Masud T, Mitzh WE: Nutrition in end stage renal diseases. In: Pereira BJG, Sayegh MH, Blake P, editors: Chronic kidney disease, dialysis and transplantation. Second edition. Philadelphia, Saunders, pp 214-231
4. Rammohan M., Kalantar-Zadeh K., Liang A., et al. Megestrol acetate in a moderate dose for the treatment of malnutrition-inflammation complex in maintenance dialysis patients. J Ren Nutr 15 (2005) 345-355
5. Ohri-Vachaspati P., and Sehgal A.R. Correlation of poor appetite among hemodialysis patients. J Ren Nutr 9 (1999) 182-185
6. Carrero J.J., Qureshi A.R., Axelsson J., et al. Comparison of nutritional and inflammatory markers in dialysis patients with reduced appetite. Am J Clin Nutr 85 (2007) 695-701
7. Scheyla José dos Santos N., Antonio Draibe S., Ayako Kamimura M., et al. Is serum albumin a marker of nutritional status in hemodialysis patients without evidence of inflammation?. Artif Organs 27 (2003) 681-686
8. Available in: http://www.cancercare.on.ca/pdfdrugs/MEGESTRO.pdf
9. Femia R.A. Goyette R, Richert E: The science of megestrol acetate delivery: potential to improve outcomes in cachexia. Biodrugs 19 (2005) 179-187
10. Cronin R.E., and Henrich W.L. Protein catabolic rate in maintenance dialysis. Up to date 15.3 (2007)
11. Carrero J.J., Aguilera A., Stenvinkel P., et al. Appetite disorders in uremia. J Ren Nutr 18 (2008) 107-113
12. Loprinzi C.L., Bernath A.M., Schaid D.J., et al. Phase III evaluation of 4 doses of megestrol acetate at therapy for patients with cancer anorexia and/or cachexia. Oncology 51 (1994) 2-7
13. Aguilera A., Selgas R., Diez J.J., et al. Anorexia in end-stage renal diseases: pathophysiology and treatment. Expert Opin Pharmacother 2 (2001) 1825-1838
14. Lein Y.H., and Ruffenach S.J. Low dose megestrol increases serum albumin in malnourished dialysis patients. Int J Artif Organs 19 (1996) 147-150
15. Boccanfuso J.A., Hutton M., and McAllister B. The effects of megestrol acetate on nutritional parameters in a dialysis population. J Ren Nutr 10 (2000) 36-43
16. Costero O., Bajo M.A., del Peso G., et al. Treatment of anorexia and malnutrition in peritoneal dialysis patients with megestrol acetate. Adv Perit Dial 20 (2004) 209-212