Effect of Liver Regeneration on the Pharmacokinetics of Immunosuppressive Drugs

Transplantation Proceedings

Volumn 41, Issue 1, 2009, Pages 379-381

  Lodewijk, L ^a   Mall, A ^a   Spearman, C W ^a   Kahn, D ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN; CYTOCHROME P450; IMMUNOSUPPRESSIVE AGENT; RAPAMYCIN; TACROLIMUS;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; GRAFT REJECTION; IMMUNOSUPPRESSIVE TREATMENT; INHIBITION KINETICS; LIVER GRAFT; LIVER REGENERATION; MALE; NONHUMAN; PARTIAL HEPATECTOMY; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RAT;

ANIMALS; AREA UNDER CURVE; CYCLOSPORINE; HEPATECTOMY; IMMUNOSUPPRESSIVE AGENTS; LIVER REGENERATION; MALE; RATS; RATS, LONG-EVANS; SIROLIMUS; TACROLIMUS;

EID: 60649087917     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2008.10.055     Document Type: Article

References (4)

1. Kahn D., van Hoorn-Hickman R., McLeod H., et al. The stimulatory effect of a partially hepatectomized axillary graft upon the host liver. S Afr Med J 61 (1982) 362
2. Starkel P., Laurent S., Petit M., et al. Early down-regulation of cytochrome P450-3A and 2E1 in the regenerating rat liver is not related to the loss of liver mass or the process of cell proliferation. Liver 20 (2000) 405
3. Fausto N. Liver regeneration: from laboratory to clinic. Liver Transpl 7 (2001) 835
4. Michalopoulos G.K., and DeFrances M.C. Liver regeneration. Science 276 (1997) 60