Vaginal microbicide adherence biomarkers should be validated

The Lancet

Volumn 373, Issue 9665, 2009, Pages 721-

  van de Wijgert, Janneke ^a   Jones, Heidi ^b   Kilmarx, Peter H ^c  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b NewYork Presbyterian Hospital   (United States)

^c CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MICROBICIDE; ANTIINFECTIVE AGENT; BIOLOGICAL MARKER;

ACCURACY; CORRELATION ANALYSIS; GEL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INSTRUMENT; LETTER; PATIENT COMPLIANCE; PRIORITY JOURNAL; SELF REPORT; SEXUAL BEHAVIOR; SEXUALITY; STAINING; VALIDITY; CLINICAL TRIAL; FEMALE; NOTE; REPRODUCIBILITY; VAGINA DISEASE;

ANTI-INFECTIVE AGENTS; BIOLOGICAL MARKERS; CLINICAL TRIALS AS TOPIC; FEMALE; HUMANS; PATIENT COMPLIANCE; REPRODUCIBILITY OF RESULTS; VAGINAL DISEASES;

EID: 60649087911     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(09)60437-2     Document Type: Letter

References (4)

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2. Wallace A.R., Teitelbaum A., Wan L., et al. Determining the feasibility of utilizing the microbicide applicator compliance assay for use in clinical trials. Contraception 76 (2007) 53-56
3. Wallace A., Mitchell T., Maguire R., Sudol K.M., and Phillips D.M. Assay for establishing whether microbicide applicators have been exposed to the vagina. Sex Transm Dis 31 (2004) 465-468
4. Karim SA, Coletti A, Richardson B, et al. Safety and effectiveness of vaginal microbicides BufferGel and 0.5% PRO 2000/5 gel for the prevention of HIV infection in women: results of the HPTN 035 trial. 16th Conference on Retroviruses and Opportunistic Infections; Feb 8-11, 2009; Montreal, Canada (abstr 48LB).