The FUSE binding proteins FBP1 and FBP3 are potential c-myc regulators in renal, but not in prostate and bladder cancer

BMC Cancer

Volumn 8, Issue , 2008, Pages

  Weber, Achim ^a   Kristiansen, Ilka ^a   Johannsen, Manfred ^b   Oelrich, Beibei ^b   Scholmann, Katharina ^c   Gunia, Sven ^d   May, Matthias ^e   Meyer, Hellmuth Alexander ^b   Behnke, Silvia ^a   Moch, Holger ^a   Kristiansen, Glen ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c Charité Campus Benjamin Franklin Medical Center   (Germany)

^d HELIOS Klinikum Bad Saarow   (Germany)

^e NONE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; FAR UPSTREAM ELEMENT BINDING PROTEIN; KI 67 ANTIGEN; MYC PROTEIN; PROSTATE SPECIFIC ANTIGEN; PROTEIN FBP1; PROTEIN FBP2; PROTEIN FBP3; UNCLASSIFIED DRUG; FUBP1 PROTEIN, HUMAN; FUBP3 PROTEIN, HUMAN; HELICASE; MYCBP PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ADULT; ARTICLE; BLADDER CANCER; CANCER CELL; CANCER GRADING; CELL PROLIFERATION; GENE CONTROL; GENE EXPRESSION; GENE LOCATION; GENETIC ASSOCIATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KIDNEY CARCINOMA; MAJOR CLINICAL STUDY; PROSTATE CANCER; TISSUE MICROARRAY; UPREGULATION; BLADDER TUMOR; CHI SQUARE DISTRIBUTION; GENE EXPRESSION REGULATION; KIDNEY TUMOR; MALE; METABOLISM; MIDDLE AGED; NONPARAMETRIC TEST; PATHOLOGY; PHYSIOLOGY; PROSTATE TUMOR; UROGENITAL TRACT TUMOR;

CHI-SQUARE DISTRIBUTION; DNA HELICASES; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; KIDNEY NEOPLASMS; MALE; MIDDLE AGED; PROSTATIC NEOPLASMS; STATISTICS, NONPARAMETRIC; TISSUE ARRAY ANALYSIS; TRANSCRIPTION FACTORS; URINARY BLADDER NEOPLASMS; UROGENITAL NEOPLASMS;

EID: 60649085175     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-8-369     Document Type: Article

References (25)

1. Davis-Smyth T Duncan RC Zheng T Michelotti G Levens D The far upstream element-binding proteins comprise an ancient family of single-strand DNA-binding transactivators J Biol Chem 1996, 271(49):31679-31687 8940189
2. Ring HZ Vameghi-Meyers V Min H Nikolic JM Black DL Francke U The mouse Fubp gene maps near the distal end of chromosome 3 Genomics 1999, 56(3):357-358 10087207
3. Ring HZ Vameghi-Meyers V Nikolic JM Min H Black DL Francke U Mapping of the KHSRP gene to a region of conserved synteny on human chromosome 19p13.3 and mouse chromosome 17 Genomics 1999, 56(3):350-352 10087204
4. He L Liu J Collins I Sanford S O'Connell B Benham CJ Levens D Loss of FBP function arrests cellular proliferation and extinguishes c-myc expression EMBO J 2000, 19(5):1034-1044 305642 10698944
5. Liu J He L Collins I Ge H Libutti D Li J Egly JM Levens D The FBP interacting repressor targets TFIIH to inhibit activated transcription Mol Cell 2000, 5(2):331-341 10882074
6. Weber A Liu J Collins I Levens D TFIIH operates through an expanded proximal promoter to fine-tune c-myc expression Mol Cell Biol 2005, 25(1):147-161 538784 15601838
7. Liu J Kouzine F Nie Z Chung HJ Elisha-Feil Z Weber A Zhao K Levens D The FUSE/FBP/FIR/TFIIH system is a molecular machine programming a pulse of c-myc expression EMBO J 2006, 25(10):2119-2130 1462968 16628215
8. Avigan MI Strober B Levens D A far upstream element stimulates c-myc expression in undifferentiated leukemia cells J Biol Chem 1990, 265(30):18538-18545 2211718
9. Duncan R Bazar L Michelotti G Tomonaga T Krutzsch H Avigan M Levens D A sequence-specific, single-strand binding protein activates the far upstream element of c-myc and defines a new DNA-binding motif Genes Dev 1994, 8(4):465-480 8125259
10. Kim MJ Park BJ Kang YS Kim HJ Park JH Kang JW Lee SW Han JM Lee HW Kim S Downregulation of FUSE-binding protein and c-myc by tRNA synthetase cofactor p38 is required for lung cell differentiation Nat Genet 2003, 34(3):330-336 12819782
11. Oster SK Ho CS Soucie EL Penn LZ The myc oncogene: MarvelouslY Complex Advances in Cancer Research 2002, 84:81-154 11885563
12. Adhikary S Eilers M Transcriptional regulation and transformation by Myc proteins Nature Reviews 2005, 6(8):635-645 16064138
13. Bova GS Carter BS Bussemakers MJ Emi M Fujiwara Y Kyprianou N Jacobs SC Robinson JC Epstein JI Walsh PC et al. Homozygous deletion and frequent allelic loss of chromosome 8p22 loci in human prostate cancer Cancer Research 1993, 53(17):3869-3873 7689419
14. Macoska JA Trybus TM Benson PD Sakr WA Grignon DJ Wojno KD Pietruk T Powell IJ Evidence for three tumor suppressor gene loci on chromosome 8p in human prostate cancer Cancer research 1995, 55(22):5390-5395 7585607
15. Sato K Qian J Slezak JM Lieber MM Bostwick DG Bergstralh EJ Jenkins RB Clinical significance of alterations of chromosome 8 in high-grade, advanced, nonmetastatic prostate carcinoma Journal of the National Cancer Institute 1999, 91(18):1574-1580 10491435
16. Christoph F Schmidt B Schmitz-Drager BJ Schulz WA Over-expression and amplification of the c-myc gene in human urothelial carcinoma Int J Cancer 1999, 84(2):169-173 10096250
17. Furge KA Chen J Koeman J Swiatek P Dykema K Lucin K Kahnoski R Yang XJ Teh BT Detection of DNA copy number changes and oncogenic signaling abnormalities from gene expression data reveals MYC activation in high-grade papillary renal cell carcinoma Cancer Research 2007, 67(7):3171-3176 17409424
18. Schraml P Kononen J Bubendorf L Moch H Bissig H Nocito A Mihatsch MJ Kallioniemi OP Sauter G Tissue microarrays for gene amplification surveys in many different tumor types Clin Cancer Res 1999, 5(8):1966-1975 10473073
19. Strefford JC Stasevich I Lane TM Lu YJ Oliver T Young BD A combination of molecular cytogenetic analyses reveals complex genetic alterations in conventional renal cell carcinoma Cancer Genet Cytogenet 2005, 159(1):1-9 15860350
20. Chung HJ Liu J Dundr M Nie Z Sanford S Levens D FBPs are calibrated molecular tools to adjust gene expression Mol Cell Biol 2006, 26(17):6584-6597 1592819 16914741
21. Kristiansen G Schluns K Yongwei Y Denkert C Dietel M Petersen I CD24 is an independent prognostic marker of survival in nonsmall cell lung cancer patients British Journal of Cancer 2003, 88(2):231-236 12610508
22. He L Weber A Levens D Nuclear targeting determinants of the far upstream element binding protein, a c-myc transcription factor Nucleic Acids Res 2000, 28(22):4558-]4565 113884 11071946
23. Liu J Akoulitchev S Weber A Ge H Chuikov S Libutti D Wang XW Conaway JW Harris CC Conaway RC et al. Defective interplay of activators and repressors with TFIH in xeroderma pigmentosum Cell 2001, 104(3):353-363 11239393
24. van Tilborg AA Groenfeld LE Kwast van der TH Zwarthoff EC Evidence for two candidate tumour suppressor loci on chromosome 9q in transitional cell carcinoma (TCC) of the bladder but no homozygous deletions in bladder tumour cell lines British Journal of Cancer 1999, 80(3-4):489-494 10408858
25. Kimura F Florl AR Seifert HH Louhelainen J Maas S Knowles MA Schulz WA Destabilization of chromosome 9 in transitional cell carcinoma of the urinary bladder British Journal of Cancer 2001, 85(12):1887-1893 11747331