Men’s Health, Low Testosterone, and Diabetes Individualized

Diabetes Educator

Volumn 34, Issue 5_suppl, 2008, Pages 97S-112S

  Rice, Donna ^a   Brannigan, Robert E ^b   Campbell, R Keith ^c   Fine, Shari ^d   Jack, Leonard ^e   Nelson, Joseph B ^f   Regan Klich, Janet ^g  

^a Botsford Center for Lifestyle Management   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c WASHINGTON STATE UNIVERSITY   (United States)

^d The Christ Hospital   (United States)

^e LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^f Golden Valley   (United States)

^g MICHAEL REESE HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TESTOSTERONE;

ARTICLE; BLOOD; HEALTH STATUS; HUMAN; HYPOGONADISM; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; SELF CARE;

DIABETES MELLITUS, TYPE 2; HEALTH STATUS; HUMANS; HYPOGONADISM; MALE; MEN; SELF CARE; TESTOSTERONE;

EID: 60549115133     PISSN: 01457217     EISSN: 15546063     Source Type: Journal    
DOI: 10.1177/0145721708327143     Document Type: Article

References (70)

1. Seftel AD Male hypogonadism. Part I: epidemiology of hypogonadism. Int J Impot Res.2006;18:115-120.
2. Fukui M., Kitagawa Y., Ose H., Hasegawa G., Yoshikawa T., Nakamura N. Role of endogenous androgen against insulin resistance and atherosclerosis in men with type 2 diabetes. Curr Diabetes Rev. 2007;3:25-31.
3. Fukui M., Soh J., Tanaka M., et al. Low serum testosterone concentration in middle-aged men with type 2 diabetes. Endocrine J. 2007;54:871-877.
4. Miner MM, Sadovsky R. Evolving issues in male hypogonadism: evaluation, management, and related comorbidities. Cleveland Clin J Med. 2007;74:S38-S46.
5. Ding EL, Song Y., Malik VS, Liu S. Sex differences of endogenous sex hormones and risk of type 2 diabetes. A systematic review and meta-analysis. JAMA. 2006;295:1288-1299.
6. Rice D., Brannigan RE, Campbell RK, et al. Men's health, low T, and diabetes: customized treatment, a multidisciplinary approach [transcript]. Consensus Summit Discussion. June 26, 2008.
7. Wheeler MJ, Barnes SC The measurement of testosterone in the diagnosis of hypogonadism in the ageing male. Clin Endocrinol (Oxf). Epub ahead of print, June 25, 2008.
8. Bhasin S., Cunningham GR, Hayes FJ, et al. Testosterone therapy in adult men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2006;91:1995-2010.
9. Morley JE, Perry HM III, Kevorkian RT, Patrick P. Comparison of screening questionnaires for the diagnosis of hypogonadism. Maturitas. 2006;53:424-429.
10. Corona G., Mannucci E., Petrone L., et al. ANDROTEST: a structured interview for the screening of hypogonadism in patients with sexual dysfunction. J Sex Med. 2006;3:706-715.
11. AACE Hypogonadism Task Force. American Association of Clinical Endocrinologists medical guidelines for clinical practice for the evaluation and treatment of hypogonadism in adult male patients-2002 update. Endocrine Pract.2002;8:439-456.
12. Nieschlag E., Swerdloff R., Behre HM, et al. Investigation, treatment and monitoring of late-onset hypogonadism in males. ISA, ISSAM, and EAU recommendations. Eur Urol.2005;48:1-4.
13. Rhoden EL, Morgentaler A. Risks of testosterone-replacement therapy and recommendations for monitoring. N Engl J Med. 2004;350:482-492.
14. Jones TH Testosterone replacement therapy. Br J Hosp Med (Lond). 2007;68:547-553.
15. Hong BS, Ahn TY Recent trends in the treatment of testosterone deficiency syndrome. Int J Urol. 2007;14:981-985.
16. Bain J. The many faces of testosterone. Clin Interv Aging. 2007;2:567-576.
17. Kapoor D., Goodwin E., Channer KS, Jones TH Testosterone replacement therapy improves insulin resistance, glycaemic control, visceral adiposity and hypercholesterolaemia in hypogonadal men with type 2 diabetes. Eur J Endocrinol. 2006;154:899-906.
18. Margo K., Winn R. Testosterone treatments: why, when, and how?Am Fam Physician. 2006;73:1591-1598.
19. Leichtnam M-L., Rolland H., Wüthrich P., Guy RH Testosterone hormone replacement therapy: state-of-the-art and emerging technologies. Pharm Res. 2006;23:1117-1132.
20. Gooren LJ, Behre HM, Saad F., Frank A., Schwerdt S. Diagnosing and treating testosterone deficiency in different parts of the world: results from global market research. Aging Male. 2007;10:173-181.
21. Ohl DA, Quallich SA Clinical hypogonadism and androgen replacement therapy: an overview. Urol Nurs. 2006;26:253-269.
22. McNicholas T., Ong T. Review of Testim® gel. Expert Opin Pharmacother. 2006;7:477-484.
23. Kapoor D., Aldred H., Clark S., Channer KS, Jones TH Clinical and biochemical assessment of hypogonadism in men with type 2 diabetes: correlations with bioavailable testosterone and visceral adiposity. Diabetes Care. 2007;30:911-917.
24. Beg S., Al-Khoury L., Cunningham GR Testosterone replacement in men. Curr Opin Endocrinol Diabetes Obes.2008;15:364-370.
25. Tostain JL, Blanc F. Testosterone deficiency: a common, unrecognized syndrome. Nat Clin Pract Urol. 2008;5:388-396.
26. Dhindsa S., Prabhakar S., Sethi M., Bandyopadhyay A., Chaudhuri A., Dandona P. Frequent occurrence of hypogonadotropic hypogonadism in type 2 diabetes. J Clin Endocrinol Metab. 2004;89:5462-5468.
27. Kapoor D., Malkin CJ, Channer KS, Jones TH Androgens, insulin resistance and vascular disease in men. Clin Endocrinol. 2005;63:239-250.
28. Mayo Clinic. Male menopause: myth or reality?http://www.mayoclinic.com/print/male-menopause/MC00058/METHOD=print. Accessed September 5, 2008.
29. Harman SM, Metter EJ, Tobin JD, et al. Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging. J Clin Endocrinol Metab. 2001;86:724-731.
30. Mulligan T., Frick MF, Zuraw QC, Stemhagen A., McWhirter C. Prevalence of hypogonadism in males aged at least 45 years: the HIM study. Int J Clin Pract. 2006;60:762-769.
31. Gould DC, Kirby RS, Amoroso P. Hypoandrogen-metabolic syndrome: a potentially common and underdiagnosed condition in men. Int J Clin Pract. 2007;61:341-344.
32. D'Arrigo T. Research profile (Frances J. Hayes, MD). Low testosterone. Tough on insulin sensitivity. Diabetes Forecast. 2007;60:63-65.
33. Tsai EC, Matsumoto AM, Fujimoto WY, Boyko EJ Association of bioavailable, free, and total testosterone with insulin resistance: influence of sex hormone-binding globulin and body fat. Diabetes Care. 2004;27:861-868.
34. Stellato RK, Feldman HA, Hamdy O., Horton ES, McKinlay JB Testosterone, sex hormone-binding globulin, and the development of type 2 diabetes in middle-aged men. Prospective results from the Massachusetts Male Aging Study. Diabetes Care. 2000;23:490-494.
35. Oh J-Y., Barrett-Connor E., Wedick NM, Wingard DL Endogenous sex hormones and the development of type 2 diabetes in older men and women: the Rancho Bernardo Study. Diabetes Care. 2002;25:55-60.
36. Grossmann M., Thomas MC, Panagiotopoulos S., et al. Low testosterone levels are common and associated with insulin resistance in men with diabetes. J Clin Endocrinol Metab. 2008;93: 1834-1840.
37. US Department of Health and Human Services, Centers for Disease Control and Prevention. National diabetes fact sheet, 2007. http://www.cdc.gov/diabetes/pubs/pdf/ndfs_2007.pdf. Accessed July 22, 2008.
38. Zitzmann M., Faber S., Nieschlag E. Association of specific symptoms and metabolic risks with serum testosterone in older men. J Clin Endocrinol Metab. 2006;91:4335-4343.
39. Selvin E., Feinleib M., Zhang L., et al. Androgens and diabetes in men: results from the Third National Health and Nutrition Examination Survey (NHANES III). Diabetes Care. 2007;30:234-238.
40. Tomar R., Dhindsa S., Chaudhuri A., Mohanty P., Garg R., Dandona P. Contrasting testosterone concentrations in type 1 and type 2 diabetes. Diabetes Care. 2006;29:1120-1122.
41. Spark RF Testosterone, diabetes mellitus, and the metabolic syndrome. Curr Urol Rep. 2007;8:467-471.
42. Kapoor D., Jones TH Androgen deficiency as a predictor of metabolic syndrome in aging men: an opportunity for intervention? Drugs Aging. 2008;25:357-369.
43. Behre HM, Heinemann L., Morales A., Pexman-Fieth C. Rationale, design and methods of the ESPRIT study: energy, sexual desire and body proportions with AndroGel®, testosterone 1% gel therapy, in hypogonadal men. Aging Male.2008;11:101-106.
44. Kupelian V., Hayes FJ, Link CL, Rosen R., McKinlay JB Inverse association of testosterone and the metabolic syndrome in men is consistent across race and ethnic groups. J Clin Endocrinol Metab. Epub ahead of print, June 18, 2008.
45. Muller M., den Tonkelaar I., Thijssen JH, Grobbee DE, van der Schouw YT Endogenous sex hormones in men aged 40-80 years. Eur J Endocrinol. 2003;149:583-589.
46. Haffner SM, Valdez RA, Stern MP, Katz MS Obesity, body fat distribution and sex hormones in men. Int J Obes Relat Metab Disord. 1993;17:643-649.
47. Zumoff B., Strain GW, Miller LK, et al. Plasma free and non-sex-hormone-binding-globulin-bound testosterone are decreased in obese men in proportion to their degree of obesity. J Clin Endocrinol Metab. 1990;71:929-931.
48. Meier C., Nguyen TV, Handelsman DJ, et al. Endogenous sex hormones and incident fracture risk in older men: the Dubbo Osteoporosis Epidemiology Study. Arch Intern Med. 2008;168:47-54.
49. Laughlin GA, Barrett-Connor E., Bergstrom J. Low serum testosterone and mortality in older men. J Clin Endocrinol Metab. 2008;93:68-75.
50. Kalyani RR, Gavini S., Dobs AS Male hypogonadism in systemic disease. Endocrinol Metab Clin North Am. 2007;36:333-348.
51. Amiaz R., Seidman SN Testosterone and depression in men. Curr Opin Endocrinol Diabetes Obes. 2008;15:278-283.
52. Almeida OP, Yeap BB, Hankey GJ, Jamrozik K., Flicker L. Low free testosterone concentration as a potentially treatable cause of depressive symptoms in older men. Arch Gen Psychiatry. 2008;65:283-289.
53. Morley JE, Charlton E., Patrick P., et al. Validation of a screening questionnaire for androgen deficiency in aging males. Metabolism. 2000;49:1239-1242.
54. Kapoor D., Clarke S., Channer KS, Jones TH Erectile dysfunction is associated with low bioactive testosterone levels and visceral adiposity in men with type 2 diabetes. Int J Androl. 2007;30:500-507.
55. Corona G., Mannucci E., Petrone L., et al. Association of hypogonadism and type II diabetes in men attending an outpatient erectile dysfunction clinic. Int J Impot Res. 2006;18:190-197.
56. Hormone Foundation. The Hormone Foundation's patient guide to androgen deficiency syndromes in adult men. http://www.hormone.org/Resources/Patient_Guides/upload/Androgens_and_Men_Patient_Guide.pdf. Accessed July 22, 2008.
57. Striant [package insert]. Livingston, NJ: Columbia Laboratories, Inc; 2003.
58. Androderm [package insert]. Corona, CA: Watson Pharma, Inc; 2005.
59. AndroGel [package insert]. Marietta, GA: Solvay Pharmaceuticals, Inc; 2007.
60. Testim [package insert]. Norristown, PA: Auxilium Pharmaceuticals, Inc; 2003.
61. Thomas SR, Evans PJ, Holland PA, Biswas M. Invasive breast cancer after initiation of testosterone replacement therapy in a man-a warning to endocrinologists [case report]. Endocrine Pract. 2008;14:201-203.
62. Platano G., Margraf J., Alder J., Bitzer J. Frequency and focus of sexual history taking in male patients-a pilot study conducted among Swiss general practitioners and urologists. J Sex Med. 2008;5:47-59.
63. Snyder PJ, Peachey H., Hannoush P., et al. Effect of testosterone treatment on bone mineral density in men over 65 years of age. J Clin Endocrinol Metab. 1999;84:1966-1972.
64. Bhasin S., Storer TW, Berman N., et al. Testosterone replacement increases fat-free mass and muscle size in hypogonadal men. J Clin Endocrinol Metab. 1997:82:407-413.
65. Katznelson L., Finkelstein JS, Schoenfeld DA, Rosenthal DI, Anderson EJ, Klibanski A. Increase in bone density and lean body mass during testosterone administration in men with acquired hypogonadism. J Clin Endocrinol Metab. 1996;81: 4358-4365.
66. Steidle CP New advances in the treatment of hypogonadism in the aging male. Rev Urol.2003;(5 suppl 1):S34-S40.
67. Basu R., Dalla Man C., Campioni M., et al. Effect of 2 years of testosterone replacement on insulin secretion, insulin action, glucose effectiveness, hepatic insulin clearance, and postprandial glucose turnover in elderly men. Diabetes Care. 2007;30:1972-1978.
68. Shabsigh R., Arver S., Channer KS, et al. The triad of erectile dysfunction, hypogonadism and the metabolic syndrome. Int J Clin Pract. 2008;62:791-798.
69. Rice D., Jack L. Jr. Use of an assessment tool to enhance diabetes educators' ability to identify erectile dysfunction. Diabetes Educ. 2006;32:373-380.
70. American Diabetes Association. Your health care team. http://www.diabetes.org/utils/printthispage.jsp?PageID=HEALTHCARETEAM_238284.Accessed June 22, 2008.