메뉴 건너뛰기




Volumn 1788, Issue 3, 2009, Pages 615-622

The YheI/YheH heterodimer from Bacillus subtilis is a multidrug ABC transporter

Author keywords

ABC transporter; ATP binding cassette; Drug transport; Multidrug; Overexpression

Indexed keywords

ABC TRANSPORTER; HETERODIMER;

EID: 60549113479     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamem.2008.12.012     Document Type: Article
Times cited : (36)

References (74)
  • 1
    • 0026621245 scopus 로고
    • ABC transporters: from microorganisms to man
    • Higgins C.F. ABC transporters: from microorganisms to man. Annu. Rev. Cell Biol. 8 (1992) 67-113
    • (1992) Annu. Rev. Cell Biol. , vol.8 , pp. 67-113
    • Higgins, C.F.1
  • 3
    • 33846040629 scopus 로고    scopus 로고
    • TransportDB: a comprehensive database resource for cytoplasmic membrane transport systems and outer membrane channels
    • Ren Q., Chen K., and Paulsen I.T. TransportDB: a comprehensive database resource for cytoplasmic membrane transport systems and outer membrane channels. Nucleic Acids Res. 35 (2007) D274-D279
    • (2007) Nucleic Acids Res. , vol.35
    • Ren, Q.1    Chen, K.2    Paulsen, I.T.3
  • 4
    • 3943062954 scopus 로고    scopus 로고
    • ATP-binding cassette transporters in bacteria
    • Davidson A.L., and Chen J. ATP-binding cassette transporters in bacteria. Annu. Rev. Biochem. 73 (2004) 241-268
    • (2004) Annu. Rev. Biochem. , vol.73 , pp. 241-268
    • Davidson, A.L.1    Chen, J.2
  • 5
    • 44949249999 scopus 로고    scopus 로고
    • Structure, function, and evolution of bacterial ATP-binding cassette systems
    • Davidson A.L., Dassa E., Orelle C., and Chen J. Structure, function, and evolution of bacterial ATP-binding cassette systems. Microbiol. Mol. Biol. Rev. 72 (2008) 317-364
    • (2008) Microbiol. Mol. Biol. Rev. , vol.72 , pp. 317-364
    • Davidson, A.L.1    Dassa, E.2    Orelle, C.3    Chen, J.4
  • 6
    • 33846700429 scopus 로고    scopus 로고
    • Intracellular peptide transporters in human-compartmentalization of the "peptidome"
    • Herget M., and Tampe R. Intracellular peptide transporters in human-compartmentalization of the "peptidome". Pflugers Arch. 453 (2007) 591-600
    • (2007) Pflugers Arch. , vol.453 , pp. 591-600
    • Herget, M.1    Tampe, R.2
  • 7
  • 8
    • 34447311648 scopus 로고    scopus 로고
    • Uptake or extrusion: crystal structures of full ABC transporters suggest a common mechanism
    • Dawson R.J., Hollenstein K., and Locher K.P. Uptake or extrusion: crystal structures of full ABC transporters suggest a common mechanism. Mol. Microbiol. 65 (2007) 250-257
    • (2007) Mol. Microbiol. , vol.65 , pp. 250-257
    • Dawson, R.J.1    Hollenstein, K.2    Locher, K.P.3
  • 10
    • 33947260230 scopus 로고    scopus 로고
    • Molecular mechanisms of antibacterial multidrug resistance
    • Alekshun M.N., and Levy S.B. Molecular mechanisms of antibacterial multidrug resistance. Cell 128 (2007) 1037-1050
    • (2007) Cell , vol.128 , pp. 1037-1050
    • Alekshun, M.N.1    Levy, S.B.2
  • 11
    • 33646251815 scopus 로고    scopus 로고
    • Clinically relevant chromosomally encoded multidrug resistance efflux pumps in bacteria
    • Piddock L.J. Clinically relevant chromosomally encoded multidrug resistance efflux pumps in bacteria. Clin. Microbiol. Rev. 19 (2006) 382-402
    • (2006) Clin. Microbiol. Rev. , vol.19 , pp. 382-402
    • Piddock, L.J.1
  • 12
    • 0036074018 scopus 로고    scopus 로고
    • Mammalian abc transporters in health and disease
    • Borst P., and Elferink R.O. Mammalian abc transporters in health and disease. Annu. Rev. Biochem. 71 (2002) 537-592
    • (2002) Annu. Rev. Biochem. , vol.71 , pp. 537-592
    • Borst, P.1    Elferink, R.O.2
  • 16
    • 0034870399 scopus 로고    scopus 로고
    • Hop resistance in the beer spoilage bacterium Lactobacillus brevis is mediated by the ATP-binding cassette multidrug transporter HorA
    • Sakamoto K., Margolles A., van Veen H.W., and Konings W.N. Hop resistance in the beer spoilage bacterium Lactobacillus brevis is mediated by the ATP-binding cassette multidrug transporter HorA. J. Bacteriol. 183 (2001) 5371-5375
    • (2001) J. Bacteriol. , vol.183 , pp. 5371-5375
    • Sakamoto, K.1    Margolles, A.2    van Veen, H.W.3    Konings, W.N.4
  • 17
    • 1642410137 scopus 로고    scopus 로고
    • A bacterial gene homologous to ABC transporters protect Oenococcus oeni from ethanol and other stress factors in wine
    • Bourdineaud J.P., Nehme B., Tesse S., and Lonvaud-Funel A. A bacterial gene homologous to ABC transporters protect Oenococcus oeni from ethanol and other stress factors in wine. Int. J. Food Microbiol. 92 (2004) 1-14
    • (2004) Int. J. Food Microbiol. , vol.92 , pp. 1-14
    • Bourdineaud, J.P.1    Nehme, B.2    Tesse, S.3    Lonvaud-Funel, A.4
  • 19
    • 15544365661 scopus 로고    scopus 로고
    • Time-resolved fluorescence resonance energy transfer shows that the bacterial multidrug ABC half-transporter BmrA functions as a homodimer
    • Dalmas O., Do Cao M.A., Lugo M.R., Sharom F.J., Di Pietro A., and Jault J.M. Time-resolved fluorescence resonance energy transfer shows that the bacterial multidrug ABC half-transporter BmrA functions as a homodimer. Biochemistry 44 (2005) 4312-4321
    • (2005) Biochemistry , vol.44 , pp. 4312-4321
    • Dalmas, O.1    Do Cao, M.A.2    Lugo, M.R.3    Sharom, F.J.4    Di Pietro, A.5    Jault, J.M.6
  • 20
    • 0034212332 scopus 로고    scopus 로고
    • The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism
    • van Veen H.W., Margolles A., Muller M., Higgins C.F., and Konings W.N. The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism. EMBO J. 19 (2000) 2503-2514
    • (2000) EMBO J. , vol.19 , pp. 2503-2514
    • van Veen, H.W.1    Margolles, A.2    Muller, M.3    Higgins, C.F.4    Konings, W.N.5
  • 21
    • 33748644877 scopus 로고    scopus 로고
    • Structure of a bacterial multidrug ABC transporter
    • Dawson R.J., and Locher K.P. Structure of a bacterial multidrug ABC transporter. Nature 443 (2006) 180-185
    • (2006) Nature , vol.443 , pp. 180-185
    • Dawson, R.J.1    Locher, K.P.2
  • 22
    • 37649004412 scopus 로고    scopus 로고
    • Flexibility in the ABC transporter MsbA: alternating access with a twist
    • Ward A., Reyes C.L., Yu J., Roth C.B., and Chang G. Flexibility in the ABC transporter MsbA: alternating access with a twist. Proc. Natl. Acad. Sci. U. S. A. 104 (2007) 19005-19010
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 19005-19010
    • Ward, A.1    Reyes, C.L.2    Yu, J.3    Roth, C.B.4    Chang, G.5
  • 24
    • 4544337748 scopus 로고    scopus 로고
    • ydaG and ydbA of Lactococcus lactis encode a heterodimeric ATP-binding cassette-type multidrug transporter
    • Lubelski J., Mazurkiewicz P., van Merkerk R., Konings W.N., and Driessen A.J. ydaG and ydbA of Lactococcus lactis encode a heterodimeric ATP-binding cassette-type multidrug transporter. J. Biol. Chem. 279 (2004) 34449-34455
    • (2004) J. Biol. Chem. , vol.279 , pp. 34449-34455
    • Lubelski, J.1    Mazurkiewicz, P.2    van Merkerk, R.3    Konings, W.N.4    Driessen, A.J.5
  • 26
    • 34548724460 scopus 로고    scopus 로고
    • Distribution and physiology of ABC-type transporters contributing to multidrug resistance in bacteria
    • Lubelski J., Konings W.N., and Driessen A.J. Distribution and physiology of ABC-type transporters contributing to multidrug resistance in bacteria. Microbiol. Mol. Biol. Rev. 71 (2007) 463-476
    • (2007) Microbiol. Mol. Biol. Rev. , vol.71 , pp. 463-476
    • Lubelski, J.1    Konings, W.N.2    Driessen, A.J.3
  • 27
    • 0033515437 scopus 로고    scopus 로고
    • Inventory, assembly and analysis of Bacillus subtilis ABC transport systems
    • Quentin Y., Fichant G., and Denizot F. Inventory, assembly and analysis of Bacillus subtilis ABC transport systems. J. Mol. Biol. 287 (1999) 467-484
    • (1999) J. Mol. Biol. , vol.287 , pp. 467-484
    • Quentin, Y.1    Fichant, G.2    Denizot, F.3
  • 28
    • 0032483367 scopus 로고    scopus 로고
    • Identification and characterization of the structural and transporter genes for, and the chemical and biological properties of, sublancin 168, a novel lantibiotic produced by Bacillus subtilis 168
    • Paik S.H., Chakicherla A., and Hansen J.N. Identification and characterization of the structural and transporter genes for, and the chemical and biological properties of, sublancin 168, a novel lantibiotic produced by Bacillus subtilis 168. J. Biol. Chem. 273 (1998) 23134-23142
    • (1998) J. Biol. Chem. , vol.273 , pp. 23134-23142
    • Paik, S.H.1    Chakicherla, A.2    Hansen, J.N.3
  • 29
    • 0032415869 scopus 로고    scopus 로고
    • Cytochrome bd biosynthesis in Bacillus subtilis: characterization of the cydABCD operon
    • Winstedt L., Yoshida K., Fujita Y., and von Wachenfeldt C. Cytochrome bd biosynthesis in Bacillus subtilis: characterization of the cydABCD operon. J. Bacteriol. 180 (1998) 6571-6580
    • (1998) J. Bacteriol. , vol.180 , pp. 6571-6580
    • Winstedt, L.1    Yoshida, K.2    Fujita, Y.3    von Wachenfeldt, C.4
  • 30
    • 25444517605 scopus 로고    scopus 로고
    • A bacterial glutathione transporter (Escherichia coli CydDC) exports reductant to the periplasm
    • Pittman M.S., Robinson H.C., and Poole R.K. A bacterial glutathione transporter (Escherichia coli CydDC) exports reductant to the periplasm. J. Biol. Chem. 280 (2005) 32254-32261
    • (2005) J. Biol. Chem. , vol.280 , pp. 32254-32261
    • Pittman, M.S.1    Robinson, H.C.2    Poole, R.K.3
  • 31
    • 33645093693 scopus 로고    scopus 로고
    • The putative ABC transporter YheH/YheI is involved in the signalling pathway that activates KinA during sporulation initiation
    • Fukushima S., Yoshimura M., Chibazakura T., Sato T., and Yoshikawa H. The putative ABC transporter YheH/YheI is involved in the signalling pathway that activates KinA during sporulation initiation. FEMS Microbiol. Lett. 256 (2006) 90-97
    • (2006) FEMS Microbiol. Lett. , vol.256 , pp. 90-97
    • Fukushima, S.1    Yoshimura, M.2    Chibazakura, T.3    Sato, T.4    Yoshikawa, H.5
  • 33
    • 18244409616 scopus 로고    scopus 로고
    • Global transcriptional response of Bacillus subtilis to treatment with subinhibitory concentrations of antibiotics that inhibit protein synthesis
    • Lin J.T., Connelly M.B., Amolo C., Otani S., and Yaver D.S. Global transcriptional response of Bacillus subtilis to treatment with subinhibitory concentrations of antibiotics that inhibit protein synthesis. Antimicrob. Agents Chemother. 49 (2005) 1915-1926
    • (2005) Antimicrob. Agents Chemother. , vol.49 , pp. 1915-1926
    • Lin, J.T.1    Connelly, M.B.2    Amolo, C.3    Otani, S.4    Yaver, D.S.5
  • 34
    • 0000479431 scopus 로고
    • Isolation of plant DNA from fresh tissue
    • Doyle J.J., and Doyle J.L. Isolation of plant DNA from fresh tissue. Focus 12 (1990) 13-15
    • (1990) Focus , vol.12 , pp. 13-15
    • Doyle, J.J.1    Doyle, J.L.2
  • 35
    • 0037144131 scopus 로고    scopus 로고
    • Highly efficient over-production in E. coli of YvcC, a multidrug-like ATP-binding cassette transporter from Bacillus subtilis
    • Steinfels E., Orelle C., Dalmas O., Penin F., Miroux B., Di Pietro A., and Jault J.M. Highly efficient over-production in E. coli of YvcC, a multidrug-like ATP-binding cassette transporter from Bacillus subtilis. Biochim. Biophys. Acta 1565 (2002) 1-5
    • (2002) Biochim. Biophys. Acta , vol.1565 , pp. 1-5
    • Steinfels, E.1    Orelle, C.2    Dalmas, O.3    Penin, F.4    Miroux, B.5    Di Pietro, A.6    Jault, J.M.7
  • 36
    • 0019830545 scopus 로고
    • A new and convenient colorimetric determination of inorganic orthophosphate and its application to the assay of inorganic pyrophosphatase
    • Heinonen J.K., and Lahti R.J. A new and convenient colorimetric determination of inorganic orthophosphate and its application to the assay of inorganic pyrophosphatase. Anal. Biochem. 113 (1981) 313-317
    • (1981) Anal. Biochem. , vol.113 , pp. 313-317
    • Heinonen, J.K.1    Lahti, R.J.2
  • 37
    • 0023025017 scopus 로고
    • Hydrolysis of adenyl-5-yl imidodiphosphate by beef heart mitochondrial ATPase
    • Tomaszek Jr. T.A., and Schuster S.M. Hydrolysis of adenyl-5-yl imidodiphosphate by beef heart mitochondrial ATPase. J. Biol. Chem. 261 (1986) 2264-2269
    • (1986) J. Biol. Chem. , vol.261 , pp. 2264-2269
    • Tomaszek Jr., T.A.1    Schuster, S.M.2
  • 38
    • 0027524789 scopus 로고
    • Temporal activation of beta-glucanase synthesis in Bacillus subtilis is mediated by the GTP pool
    • Stulke J., Hanschke R., and Hecker M. Temporal activation of beta-glucanase synthesis in Bacillus subtilis is mediated by the GTP pool. J. Gen. Microbiol. 139 (1993) 2041-2045
    • (1993) J. Gen. Microbiol. , vol.139 , pp. 2041-2045
    • Stulke, J.1    Hanschke, R.2    Hecker, M.3
  • 39
    • 33846005808 scopus 로고    scopus 로고
    • Discovering antibiotic efficacy biomarkers: toward mechanism-specific high content compound screening
    • Freiberg C., Brunner N., Macko L., and Fischer H.P. Discovering antibiotic efficacy biomarkers: toward mechanism-specific high content compound screening. Mol. Cell Proteomics 5 (2006) 2326-2335
    • (2006) Mol. Cell Proteomics , vol.5 , pp. 2326-2335
    • Freiberg, C.1    Brunner, N.2    Macko, L.3    Fischer, H.P.4
  • 40
    • 12944327876 scopus 로고    scopus 로고
    • Discovering the mechanism of action of novel antibacterial agents through transcriptional profiling of conditional mutants
    • Freiberg C., Fischer H.P., and Brunner N.A. Discovering the mechanism of action of novel antibacterial agents through transcriptional profiling of conditional mutants. Antimicrob. Agents Chemother. 49 (2005) 749-759
    • (2005) Antimicrob. Agents Chemother. , vol.49 , pp. 749-759
    • Freiberg, C.1    Fischer, H.P.2    Brunner, N.A.3
  • 42
    • 8744308029 scopus 로고    scopus 로고
    • Properties of overlapping genes are conserved across microbial genomes
    • Johnson Z.I., and Chisholm S.W. Properties of overlapping genes are conserved across microbial genomes. Genome Res. 14 (2004) 2268-2272
    • (2004) Genome Res. , vol.14 , pp. 2268-2272
    • Johnson, Z.I.1    Chisholm, S.W.2
  • 43
    • 42949152261 scopus 로고    scopus 로고
    • The efflux pump inhibitor reserpine selects multidrug-resistant Streptococcus pneumoniae strains that overexpress the ABC transporters PatA and PatB
    • Garvey M.I., and Piddock L.J. The efflux pump inhibitor reserpine selects multidrug-resistant Streptococcus pneumoniae strains that overexpress the ABC transporters PatA and PatB. Antimicrob. Agents Chemother. 52 (2008) 1677-1685
    • (2008) Antimicrob. Agents Chemother. , vol.52 , pp. 1677-1685
    • Garvey, M.I.1    Piddock, L.J.2
  • 44
    • 27644571508 scopus 로고    scopus 로고
    • Use of an efflux-deficient Streptococcus pneumoniae strain panel to identify ABC-class multidrug transporters involved in intrinsic resistance to antimicrobial agents
    • Robertson G.T., Doyle T.B., and Lynch A.S. Use of an efflux-deficient Streptococcus pneumoniae strain panel to identify ABC-class multidrug transporters involved in intrinsic resistance to antimicrobial agents. Antimicrob. Agents Chemother. 49 (2005) 4781-4783
    • (2005) Antimicrob. Agents Chemother. , vol.49 , pp. 4781-4783
    • Robertson, G.T.1    Doyle, T.B.2    Lynch, A.S.3
  • 46
    • 33846979122 scopus 로고    scopus 로고
    • Characterization of relA and codY mutants of Listeria monocytogenes: identification of the CodY regulon and its role in virulence
    • Bennett H.J., Pearce D.M., Glenn S., Taylor C.M., Kuhn M., Sonenshein A.L., Andrew P.W., and Roberts I.S. Characterization of relA and codY mutants of Listeria monocytogenes: identification of the CodY regulon and its role in virulence. Mol. Microbiol. 63 (2007) 1453-1467
    • (2007) Mol. Microbiol. , vol.63 , pp. 1453-1467
    • Bennett, H.J.1    Pearce, D.M.2    Glenn, S.3    Taylor, C.M.4    Kuhn, M.5    Sonenshein, A.L.6    Andrew, P.W.7    Roberts, I.S.8
  • 47
    • 30744447972 scopus 로고    scopus 로고
    • Identification of Listeria monocytogenes genes contributing to intracellular replication by expression profiling and mutant screening
    • Joseph B., Przybilla K., Stuhler C., Schauer K., Slaghuis J., Fuchs T.M., and Goebel W. Identification of Listeria monocytogenes genes contributing to intracellular replication by expression profiling and mutant screening. J. Bacteriol. 188 (2006) 556-568
    • (2006) J. Bacteriol. , vol.188 , pp. 556-568
    • Joseph, B.1    Przybilla, K.2    Stuhler, C.3    Schauer, K.4    Slaghuis, J.5    Fuchs, T.M.6    Goebel, W.7
  • 50
  • 52
    • 33748698411 scopus 로고    scopus 로고
    • The world of subinhibitory antibiotic concentrations
    • Davies J., Spiegelman G.B., and Yim G. The world of subinhibitory antibiotic concentrations. Curr. Opin. Microbiol. 9 (2006) 445-453
    • (2006) Curr. Opin. Microbiol. , vol.9 , pp. 445-453
    • Davies, J.1    Spiegelman, G.B.2    Yim, G.3
  • 53
    • 0036223585 scopus 로고    scopus 로고
    • Bacillus subtilis functional genomics: global characterization of the stringent response by proteome and transcriptome analysis
    • Eymann C., Homuth G., Scharf C., and Hecker M. Bacillus subtilis functional genomics: global characterization of the stringent response by proteome and transcriptome analysis. J. Bacteriol. 184 (2002) 2500-2520
    • (2002) J. Bacteriol. , vol.184 , pp. 2500-2520
    • Eymann, C.1    Homuth, G.2    Scharf, C.3    Hecker, M.4
  • 54
    • 0016795183 scopus 로고
    • Studies on the control of development. Accumulation of guanosine tetraphosphate and pentaphosphate in response to inhibition of protein synthesis in Bacillus subtilis
    • Rhaese H.J., Dichtelmuller H., and Grade R. Studies on the control of development. Accumulation of guanosine tetraphosphate and pentaphosphate in response to inhibition of protein synthesis in Bacillus subtilis. Eur. J. Biochem. 56 (1975) 385-392
    • (1975) Eur. J. Biochem. , vol.56 , pp. 385-392
    • Rhaese, H.J.1    Dichtelmuller, H.2    Grade, R.3
  • 55
    • 0036796243 scopus 로고    scopus 로고
    • Overexpression and functional characterization of an ABC (ATP-binding cassette) transporter encoded by the genes drrA and drrB of Mycobacterium tuberculosis
    • Choudhuri B.S., Bhakta S., Barik R., Basu J., Kundu M., and Chakrabarti P. Overexpression and functional characterization of an ABC (ATP-binding cassette) transporter encoded by the genes drrA and drrB of Mycobacterium tuberculosis. Biochem. J. 367 (2002) 279-285
    • (2002) Biochem. J. , vol.367 , pp. 279-285
    • Choudhuri, B.S.1    Bhakta, S.2    Barik, R.3    Basu, J.4    Kundu, M.5    Chakrabarti, P.6
  • 56
    • 0027417398 scopus 로고
    • Characterization of the adenosine triphosphatase activity of Chinese hamster P-glycoprotein
    • al-Shawi M.K., and Senior A.E. Characterization of the adenosine triphosphatase activity of Chinese hamster P-glycoprotein. J. Biol. Chem. 268 (1993) 4197-4206
    • (1993) J. Biol. Chem. , vol.268 , pp. 4197-4206
    • al-Shawi, M.K.1    Senior, A.E.2
  • 57
    • 0026722467 scopus 로고
    • Expression of the human multidrug resistance cDNA in insect cells generates a high activity drug-stimulated membrane ATPase
    • Sarkadi B., Price E.M., Boucher R.C., Germann U.A., and Scarborough G.A. Expression of the human multidrug resistance cDNA in insect cells generates a high activity drug-stimulated membrane ATPase. J. Biol. Chem. 267 (1992) 4854-4858
    • (1992) J. Biol. Chem. , vol.267 , pp. 4854-4858
    • Sarkadi, B.1    Price, E.M.2    Boucher, R.C.3    Germann, U.A.4    Scarborough, G.A.5
  • 58
    • 31844452412 scopus 로고    scopus 로고
    • Insight in eukaryotic ABC transporter function by mutation analysis
    • Frelet A., and Klein M. Insight in eukaryotic ABC transporter function by mutation analysis. FEBS Lett. 580 (2006) 1064-1084
    • (2006) FEBS Lett. , vol.580 , pp. 1064-1084
    • Frelet, A.1    Klein, M.2
  • 59
    • 0034947674 scopus 로고    scopus 로고
    • From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance
    • Litman T., Druley T.E., Stein W.D., and Bates S.E. From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance. Cell. Mol. Life Sci. 58 (2001) 931-959
    • (2001) Cell. Mol. Life Sci. , vol.58 , pp. 931-959
    • Litman, T.1    Druley, T.E.2    Stein, W.D.3    Bates, S.E.4
  • 60
    • 0033534178 scopus 로고    scopus 로고
    • The purified and functionally reconstituted multidrug transporter LmrA of Lactococcus lactis mediates the transbilayer movement of specific fluorescent phospholipids
    • Margolles A., Putman M., van Veen H.W., and Konings W.N. The purified and functionally reconstituted multidrug transporter LmrA of Lactococcus lactis mediates the transbilayer movement of specific fluorescent phospholipids. Biochemistry 38 (1999) 16298-16306
    • (1999) Biochemistry , vol.38 , pp. 16298-16306
    • Margolles, A.1    Putman, M.2    van Veen, H.W.3    Konings, W.N.4
  • 61
    • 0030822996 scopus 로고    scopus 로고
    • P-glycoprotein-mediated Hoechst 33342 transport out of the lipid bilayer
    • Shapiro A.B., Corder A.B., and Ling V. P-glycoprotein-mediated Hoechst 33342 transport out of the lipid bilayer. Eur. J. Biochem. 250 (1997) 115-121
    • (1997) Eur. J. Biochem. , vol.250 , pp. 115-121
    • Shapiro, A.B.1    Corder, A.B.2    Ling, V.3
  • 62
    • 0030782511 scopus 로고    scopus 로고
    • Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities
    • Shapiro A.B., and Ling V. Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities. Eur. J. Biochem. 250 (1997) 130-137
    • (1997) Eur. J. Biochem. , vol.250 , pp. 130-137
    • Shapiro, A.B.1    Ling, V.2
  • 65
    • 0034817367 scopus 로고    scopus 로고
    • Analysis of a complete library of putative drug transporter genes in Escherichia coli
    • Nishino K., and Yamaguchi A. Analysis of a complete library of putative drug transporter genes in Escherichia coli. J. Bacteriol. 183 (2001) 5803-5812
    • (2001) J. Bacteriol. , vol.183 , pp. 5803-5812
    • Nishino, K.1    Yamaguchi, A.2
  • 66
    • 0030756063 scopus 로고    scopus 로고
    • Natural functions of bacterial multidrug transporters
    • Neyfakh A.A. Natural functions of bacterial multidrug transporters. Trends Microbiol. 5 (1997) 309-313
    • (1997) Trends Microbiol. , vol.5 , pp. 309-313
    • Neyfakh, A.A.1
  • 67
    • 0036015623 scopus 로고    scopus 로고
    • Mystery of multidrug transporters: the answer can be simple
    • Neyfakh A.A. Mystery of multidrug transporters: the answer can be simple. Mol. Microbiol. 44 (2002) 1123-1130
    • (2002) Mol. Microbiol. , vol.44 , pp. 1123-1130
    • Neyfakh, A.A.1
  • 68
    • 0029013337 scopus 로고
    • Two highly similar multidrug transporters of Bacillus subtilis whose expression is differentially regulated
    • Ahmed M., Lyass L., Markham P.N., Taylor S.S., Vazquez-Laslop N., and Neyfakh A.A. Two highly similar multidrug transporters of Bacillus subtilis whose expression is differentially regulated. J. Bacteriol. 177 (1995) 3904-3910
    • (1995) J. Bacteriol. , vol.177 , pp. 3904-3910
    • Ahmed, M.1    Lyass, L.2    Markham, P.N.3    Taylor, S.S.4    Vazquez-Laslop, N.5    Neyfakh, A.A.6
  • 70
    • 0028307550 scopus 로고
    • Phosphatidylcholine translocase: a physiological role for the mdr2 gene
    • Ruetz S., and Gros P. Phosphatidylcholine translocase: a physiological role for the mdr2 gene. Cell 77 (1994) 1071-1081
    • (1994) Cell , vol.77 , pp. 1071-1081
    • Ruetz, S.1    Gros, P.2
  • 72
    • 0034799367 scopus 로고    scopus 로고
    • Efflux-mediated drug resistance in Gram-positive bacteria
    • Markham P.N., and Neyfakh A.A. Efflux-mediated drug resistance in Gram-positive bacteria. Curr. Opin. Microbiol. 4 (2001) 509-514
    • (2001) Curr. Opin. Microbiol. , vol.4 , pp. 509-514
    • Markham, P.N.1    Neyfakh, A.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.