At the crossroads: Mucosal immunology of the larynx

Mucosal Immunology

Volumn 2, Issue 2, 2009, Pages 122-128

  Thibeault, S L ^a   Rees, L ^b   Pazmany, L ^c   Birchall, M A ^b  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

TOBACCO SMOKE;

ANTIGEN PRESENTATION; BACTERIAL COLONIZATION; BREATHING; ENTERITIS; GASTROESOPHAGEAL REFLUX; GASTROINTESTINAL TRACT; HEMATOPOIETIC CELL; HUMAN; IMMUNE RESPONSE; IMMUNOMODULATION; LARYNGITIS; LARYNX; LARYNX MUCOSA; MUCOSAL IMMUNITY; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY SYSTEM; RESPIRATORY TRACT INFLAMMATION; REVIEW; SWALLOWING; VOICE;

EID: 60549111214     PISSN: 19330219     EISSN: None     Source Type: Journal    
DOI: 10.1038/mi.2008.82     Document Type: Review

References (41)

1. Jacobson, B.H., Johnson, A. & Grywalski, C. The voice handicap index (VHI): Development and validation. Am. J. Speech Lang. Pathol. 6, 66-70 (1997).
2. Ma, E.P. & Yiu, E.M. Voice activity and participation profile: Assessing the impact of voice disorders on daily activities. J. Speech Lang. Hear. Res. 44, 511-524 (2001).
3. Roy, N. et al. Three treatments for teachers with voice disorders: a randomized clinical trial. J. Speech Lang. Hear. Res. 46, 670-688 (2003).
4. Verdolini, K. & Ramig, L. Review: Occupational risks for voice problems. Logoped Phoniatr. Vocol. 26, 37-46 (2001).
5. Coyle, S.M., Weinrich, B.D. & Stemple, J.C. Shifts in relative prevalence of laryngeal pathology in a treatment-seeking population. J. Voice 15, 424-440 (2001).
6. Barker, E., Haverson, K., Stokes, C.R., Bitchall, M. & Bailey, M. The larynx as an immunological organ: Immunological architecture in the pig as a large animal model. Clin. Exp. Immunol. 143, 6-14 (2006).
7. Stell, P.M., Stell, I.M., & Watt, J. Age changes in the epithelial lining of the human larynx. Gerontology 28, 208-214 (1982).
8. Innes, A.L. et al. Epithelial mucin stores are increased In the large airways of smokers with airflow obstruction. Chest 130 1102-1108 (2006).
9. Gillet, S. et al. Molecular identification of the bacterial flora of the larynx. Clin. Otolaryngol. (in press).
10. Gillet, S., Rees, L.E., Coogan, T., Birchall, M. & Bailey M. Characterization of the bacterial flora of the larynx. Clin. Otolaryngol. 31, 583 (2006).
11. Rees, L.E., Ayoub, O., Birchall, M.A., Haverson, K. & Balley, M. Quantiatitive immunofluorescence to measure MHC Class II expression on laryngeal epithelium. Clin. Exp. Immunol. 134, 497-502 (2003).
12. Rees, L.E., Gunasekaran, S., Sipaul, F, Birchall, M.A. & Bailey, M. The isolation and characterisation of primary human laryngeal epithelial cells. Mol. Immunol. 43, 725-730 (2006).
13. Jecker, P., Ptok, M., Pabst, R. & Westermann, J. Distribution of immunocompetent calls in various areas in the normal laryngeal mucosa of the rat. Eur. Arch. Otorhinolaryngol. 253, 142-146 (1996).
14. Jecker, P. et al. Acute laryngitis in the rat induced by Moraxella catarrhalis and Bordetella pertussis: Number of neutrophils, dendritic cells, and T and B lymphocytes accumulating during infection in the laryngeal mucosa strongly differs in adjacent locations. Pedietr Res. 46, 760-766 (1999).
15. Jecker, P., Mann, W.J., McWilliam, A.S. & Holt, P.G. Dendritic cell influx differs between the subglottic and glottic mucosae during acute laryngotracheitis induced by a broad spectrum of stimuli. Ann. Otol., Rhinol. Laryngol. 111, 567-572 (2002).
16. Debertin, A.S. et al. Coincidence of different structures of mucosa-associated lymphoid tissue (MALT) in the respiratory tract of children: No indications for enhanced mucosal immunostimulation in sudden infant death syndrome (SIDS). Clin. Exp. Immunol. 146 54-59 (2006).
17. Kracke, A. et al. Larynx-associated lymphoid tissue (LALT) in young children. Anat. Rec. 248, 413-420 (1997).
18. Hiller, A.S., Tschernig, T, Kleemann, W.J. & Pabst, R. Bronchus-associated lymphoid tissue (BALT) and larynx-associated-lymphoid tissue (LALT) are found at different frequencies in children, adolescents and adults. Scand. J. Immunol. 47, 159-162 (1998).
19. Kutta, H., Steven, P., Tillmann, B.N., Tsokos, M. & Paulsen, F.P. Region-specific immunological response of the different laryngeal compartments: Significance of larynx-associated lymphoid tissue. Cell Tissue Res. 311, 365-371 (2003).
20. Rees, L.E. et al. Lifestyle factors influence immunology architecture of the human larynx. Clin. Immunol. 118, 324-327 (2006).
21. Dietrich, C., Jecker, P, Tschernig, T. & Mann, W.J. Presence of dendritic cells, T lymphocytes, macrophages, B lymphocytes and glandular tissue in the human fetal larynx. Acta Otolaryngologica 124, 833-838 (2004).
22. Barker, E. et al. Early immunological changes associated with laryngeal transplantation in a major histocompatibility complex-matched pig model. Clin. Exp. Immunol. 146, 603-508 (2006).
23. Inman, C.F. et al. Validation of computer-assisted, pixel-based analysis of multiple-colour immunofluorescence histology. J. Immunol. Methods 302. 156-167 (2005).
24. Inman, C., Bailey, J.C., Cook, S. & Bailey, M. Interactions between immune cells and their microenvironment. Vet. Immunol. Immunopathol. 120, 10-19 (2007).
25. http://rsb.info.nih.gov/ii/
26. Birchall, M. et al. The development of upper airway mucosal immune architecture depends on peri-natal bacterial colonisation. Clin. Otolaryngol. 33, 299 (2008).
27. Tanaka, I., Suzuki, K., Tanaka, E. & Baba, S. Investigation of normal bacterial flora in the upper respiratory tract. Acta Otolaryngologica, Supplement 525, 44-50 (1996).
28. Kizilay, A. et al. Histopathologic examination for Helicobacter pylori as a possible etiopathogenic factor in laryngeal carcinoma. Chemotherapy 52, 80-82 (2006).
29. Akbayir, N., Basak, T., Seven, H., Sungun, A. & Erdem, L. Investigation of Helicobacter pylori colonization in laryngeal neoplasia. Eur. Arch. Otorhinolaryngol. 262, 170-172 (2005).
30. Fang, T.J., Lee, L.A., Li, H.Y., Yang, C. & Huang, C.G. Helicobacter pylori colonization in the larynges of patients with hoarseness. Laryngoscope 118, 389-393 (2008).
31. Rubin, J.S., Benjamin, E., Prior, A., Lavy, J. & Ratcliffe, P. The prevalence of Helicobacter pylori infection in benign laryngeal disorders. J. Voice 16, 87-91 (2002).
32. Borkowski, G. et al. A possible role of Helicobacter pylori infection in the etiology of chronic laryngitis. Eur Arch. Otorhinolaryngol. 254, 481-482 (1997).
33. Jaspersen, D: et al. Is chronic laryngitis associatedwith Helicobacter pylori? Results of a prospective study. Z. Gastoenterol. 36, 369-372 (1998).
34. Rees, L.E. et al. Smoking influences the immunological architecture of the human larynx. Clin. Immunol. 118, 342-347 (2006).
35. Duflo, S. et al. Differential gene expression profiling of vocal fold polyps and Reinke's edema by cDNA microarray. Ann. Otol., Rhinol. Laryngol. 115, 703-714 (2006).
36. Koufman, J.A., Amin, M.R. & Panetti, M. Prevalence of reflux in 113 consecutive patients with laryngeal and voice disorders. Otolaryngol. Head Neck Surg. 123, 385-388 (2000).
37. Karkos, P.D. & Wilson, J.A. Empiric treatment of laryngopharyngeal reflux with proton pump inhibitors: A systematic review. Laryngoscope 116, 144-148 (2006).
38. Rees, L.E. et al. The mucosal immune response to laryngopharyngeal reflux. Am. J. Respir. Crit. Care Med. 177, 1187-1193 (2008).
39. Belafsky, P.C., Postma, G.N., Amin, M.R. & Koufman, J.A. Symptoms and findings of laryngopharyngeal reflux. Ear Nose Throat J. 81, 10-13 (2002).
40. Tonti, E. et al. NKT cell help to B lymphocytes can occur independently of cognate interaction. Blood (in press).
41. Fontana, G.A. et al. Coughing in laryngectomized patients. Am. J. Respir. Crit. Care Med. 160, 1578-1584 (1999).