Hyperlipidemic chicken as a model of non-alcoholic steatohepatitis

Experimental Biology and Medicine

Volumn 234, Issue 1, 2009, Pages 10-16

  Ayala, Ignacio ^a   Castillo, Antonia Martín ^b   Adánez, Gracia ^c   Fernández Rufete, Ana ^c   Pérez, Bartolomé García ^c   Castells, Maria T ^a  

^a UNIVERSITY OF MURCIA   (Spain)

^b Allergy Section   (Spain)

^c HOSPITAL UNIVERSITARIO VIRGEN DE LA ARRIXACA   (Spain)

Author keywords

Chicken; Experimental animal model; Non alcoholic steatohepatitis (NASH)

Indexed keywords

CHOLESTEROL; LIVER ENZYME; PALM OIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIET; EXPERIMENTAL MODEL; FAT INTAKE; HISTOPATHOLOGY; HYPERCHOLESTEROLEMIA; HYPERLIPIDEMIA; HYPERTRIGLYCERIDEMIA; INFLAMMATORY INFILTRATE; LIPID BLOOD LEVEL; LIVER CELL; LIVER FUNCTION; NONALCOHOLIC FATTY LIVER; NONHUMAN;

ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; BIOLOGICAL MARKERS; CHICKENS; CHOLESTEROL, DIETARY; DISEASE MODELS, ANIMAL; FATTY LIVER; GAMMA-GLUTAMYLTRANSFERASE; HEPATOCYTES; HYPERLIPIDEMIAS; INFLAMMATION; LIVER; MALE;

ANIMALIA; AVES;

EID: 60549095620     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.3181/0807-RM-219     Document Type: Article

References (31)

1. George J, Liddle C. Nonalcoholic fatty liver disease: pathogenesis and potential for nuclear receptors as therapeutic targets. Mol Pharmacol 5: 49-59, 2008.
2. Schreuder TCMA, Verwer BJ, van Nieukerk CMJ, Mulder CJJ. Nonalcoholic fatty liver disease: an overview of current insights in pathogenesis, diagnosis and treatment. World J Gastroenterol 14:2474-2486, 2008.
3. McCullough AJ. The epidemiology and risk factors of NASH. In: Farrell GC, George J, Hall P, McCullough AJ, Eds. Fatty Liver Disease: NASH and related disorders. Oxford: Blackwell Publishing, p23, 2005.
4. London RM, George J. Pathogenesis of NASH: animal models. Clin Liver Dis 11:55-74, 2007.
5. Cherian G, Holsonbake T, Goeger M, Bildfell R. Dietary CLA alters yolk and tissue FA composition and hepatic histopathology of laying hens. Lipids 37:751-757, 2002.
6. García Pérez B, Ayala I, Castells MT, Madrid JF, Ortega MR, Ortega JV, Ballesta J, Fernández Pardo J, Valdés M. Planimetric and histological study of the aortae in atherosclerotic chickens treated with nifedipine, verapamil and diltiazem. Histol Histopathol 18:1027-1033, 2003.
7. García Pérez B, Ayala I, Castells MT, Sánchez Polo MT, García Partida P, Valdés M. Effects of nifedipine, verapamil and diltiazem on serum biochemical parameters and aortic composition of atherosclerotic chickens. Biomed Pharmacother 59:1-7, 2005.
8. Libby P. Inflammation in atherosclerosis. Nature 420:868-874, 2002.
9. Kostner GM, Molinari E, Pichler P. Evaluation of a new HDL2/HDL3 quantitation method based on precipitation with polyethylene glycol. Clin Chem Acta 148:139-147, 1985.
10. Brunt EM, Janney CG, Di Bisceglie AM, Neuschwander-Tetri BA, Bacon BR. Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions. Am J Gastroenterol 94:2467-2474, 1999.
11. Angulo P. Nonalcoholic fatty liver disease. N Engl J Med 346:1221-1231, 2002.
12. Kleiner DE, Brunt EM, Van Natta M, Behling C, Contos MJ, Cummings OW, Ferrell LD, Liu YC, Torbenson MS, Unalp-Arida A, Yeh M, McCullough AJ, Sanyal AJ, Nonalcoholic Steatohepatitis Clinical Research Network. Design and validation of a histologic scoring system for non-alcoholic fatty liver disease. Hepatology 41: 1313-1321, 2005.
13. Ludwig J, McGill DB, Lindor KD. Review: nonalcoholic steatohepatitis. J Gastroenterol Hepatol 12:398-403, 1997.
14. Rector RS, Thyfault JP, Wei Y, Ibdah JA. Non-alcoholic fatty liver disease and the metabolic syndrome: an update. World J Gastroenterol 14:185-192, 2008.
15. Stevens L. Avian Biochemistry and Molecular Biology. Cambridge: Cambridge University Press, p74, 1996.
16. Hermier D, Guy G, Guillaumin S, Davail S, Andre JM, Hoo-Paris R. Differential channelling of liver lipids in relation to susceptibility to hepatic steatosis in two species of ducks. Comp Biochem Physiol B Biochem Mol Biol 135:663-675, 2003.
17. Targher G, Bertolini L, Padovani R, Poli F, Scala L, Zenari L, Zoppini G, Falezza G. Non-alcoholic fatty liver disease is associated with carotid artery wall thickness in diet-controlled type 2 diabetic patients. J Endocrinol Invest 29:55-60, 2006.
18. Simpson CF, Harms RH. Aortic atherosclerosis in nonlaying hens with fatty liver syndrome. Avian Dis 27:652-659, 1983.
19. Cortez-Pinto H, Camilo ME, Baptista A, De Oliveira AG, De Moura MC. Non-alcoholic fatty liver: another feature of the metabolic syndrome? Clin Nutr 18:353-358, 1999.
20. Ho KJ, Lawrence WD, Lewis KA, Liu LB, Taylor CB. Hereditary hyperlipidemia in nonlaying chickens. Arch Pathol 98:161-172, 1974.
21. Amagasa H, Okazaki M, Iwai S, Kumai T, Kobayashi S, Oguchi K. Enhancement of the coagulation system in spontaneously hypertensive and hyperlipidemic rats. J Atheros Thromb 12:191-197, 2005.
22. Okazaki M, Morio Y, Iwai S, Miyamoto K, Sakamoto H, Imai K, Oguchi K. Age-related changes in blood coagulation and fibrinolysis in mice fed on a high-cholesterol diet. Exp Animal 47:237-246, 1998.
23. Ichino K, Okazaki M, Usami S, Oguchi K. Involvement of enhanced coagulation and fibrinolysis system in induction of atherosclerosis in hyperlipidemic rabbits fed on a high cholesterol diet. In Vivo 11:115-123, 1997.
24. Federico A, Trappoliere F, Coppola M, D'Auria M. Relationship between dietary intake and liver histology in non-alcoholic fatty liver disease. J Hepatol 44:S251, 2006.
25. Diehl AM. Alcoholic liver disease. Med Clin North Am 73:815-830, 1989.
26. Zelber-Sagi S, Lurie Y, Nitzan-Kaluski D, Halpern Z, Oren R. Serum ALT is not a reliable screening tool for NAFLD in the general population. J Hepatol 44:S267, 2006.
27. Elkin RG, Wood KV, Hagey LR. Biliary bile acid profiles of domestic fowl as determined by high performance liquid chromatography and fast atom bombardment mass spectrometry. Comp Biochem Physiol B Biochem Mol Biol 96:157-161, 1990.
28. Cherian G, George MP. Hepatic lipid characteristic and histopathology of laying hens fed CLA or n-3 fatty acids. Lipids 39:31-36, 2004.
29. Franzen LE, Ekstedt M, Kechagias S, Bodin L. Semiquantitative evaluation overestimates the degree of steatosis in liver biopsies: a comparison to stereological point counting. Mod Pathol 18:912-916, 2005.
30. Hübscher SG. Histological assessment of non-alcoholic fatty liver disease. Histopathology 49:450-465, 2006.
31. Younossi ZM, Gramlich T, Liu YC, Matteoni C. Nonalcoholic fatty liver disease: assessment of variability in pathologic interpretations. Mod Pathol 11:560-565, 1998.