Targeted transport of 125I-labeled antibody to GFAP and AMVB1 in an experimental rat model of C6 glioma

Journal of Neuroimmune Pharmacology

Volumn 4, Issue 1, 2009, Pages 28-34

  Chekhonin, Vladimir P ^a   Baklaushev, Vladimir P ^a   Yusubalieva, Gaukhar M ^a   Gurina, Olga I ^a  

^a Serbsky National Research Center for Social and Forensic Psychiatry   (Russian Federation)

Author keywords

C6 glioma; Glial fibrillary acidic protein; Targeted delivery

Indexed keywords

ANTIGEN OF ABLUMINAL MEMBRANE OF ENDOTHELIOCYTE 1; CELL ANTIGEN; GLIAL FIBRILLARY ACIDIC PROTEIN; IMMUNOGLOBULIN G; IODINE 125; MONOCLONAL ANTIBODY ANTIGEN OF ABLUMINAL MEMBRANE OF ENDOTHELIOCYTE; MONOCLONAL ANTIBODY GLIAL FIBRILLARY ACIDIC PROTEIN; TUMOR MARKER; UNCLASSIFIED DRUG; ANTIBODY; DIAGNOSTIC AGENT; MEMBRANE ANTIGEN; RADIOACTIVE IODINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN BINDING; ARTICLE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG DELIVERY SYSTEM; DRUG TARGETING; DRUG TRANSPORT; FEMALE; GLIOBLASTOMA; ISOTOPE LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TISSUE DISTRIBUTION; ANIMAL; AUTORADIOGRAPHY; BRAIN; BRAIN TUMOR; CANCER TRANSPLANTATION; FLUORESCENT ANTIBODY TECHNIQUE; GLIOMA; HEMISPHERIC DOMINANCE; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; KIDNEY; METABOLISM; SPLEEN; SPRAGUE DAWLEY RAT; TUMOR CELL LINE;

ANIMALS; ANTIBODIES; ANTIGENS, SURFACE; AUTORADIOGRAPHY; BRAIN; BRAIN NEOPLASMS; CELL LINE, TUMOR; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; FUNCTIONAL LATERALITY; GLIAL FIBRILLARY ACIDIC PROTEIN; GLIOMA; IMMUNOGLOBULIN G; IMMUNOHISTOCHEMISTRY; IODINE RADIOISOTOPES; KIDNEY; NEOPLASM TRANSPLANTATION; RATS; RATS, SPRAGUE-DAWLEY; SPLEEN;

EID: 60549090052     PISSN: 15571890     EISSN: 15571904     Source Type: Journal    
DOI: 10.1007/s11481-008-9123-5     Document Type: Article

References (23)

1. 131I labeled antitenascin 81C6 murine monoclonal antibody in newly diagnosed patients with malignant gliomas: a phase II study J Nucl Med 46 1042 1051
2. LW Brady C Miyamoto DV Woo M Rackover J Emrich H Bender 1992 Malignant astrocytomas treated with iodine-125 labeled monoclonal antibody 425 against epidermal growth factor receptor: a phase II trial Int J Radiat Oncol Biol Phys 22 225 230
3. EB Carson-Walter J Hampton E Shue DM Geynisman PK Pillai R Sathanoori SL Madden RL Hamilton KA Walter 2005 Plasmalemmal vesicle associated protein-1 is a novel marker implicated in brain tumor angiogenesis Clin Cancer Res 11 7643 7650
4. VP Chekhonin GV Morozov IA Riabukhin 1989 Immunoenzyme detection of specific brain antigens as a criterion of the permeability of the hemato-encephalic barrier in rats following acute gamma irradiation Bull Eksp Biol Med 107 4 464 466
5. VP Chekhonin VP Baklaushev OI Gurina TB Dmitrieva EA Savchenko IP Lazarenko 2001 Immunoenzyme assay of glial fibrillary acidic protein for evaluation of functional activity of cell grafts from embryonic ventral mesencephalon in rats with experimental hemiparkinsonism Bull Exp Biol Med 131 6 550 554
6. VP Chekhonin VP Baklaushev GM Yusubalieva KA Pavlov OV Ukhova OI Gurina 2007 Modeling and immunohistochemical analysis of C6 glioma In Vivo Bull Exp Biol Med 2 65 73
7. 125I-labeled monoclonal antibodies after introvenous administration to rats with experimental C6 glioma Biomed Khim 53 532 540
8. 125I-labeled monoclonal antibodies to target proteins in experimental glioma focus Dokl Biochem Biophys 418 1 4
9. M Errede V Benagiano F Girolamo P Flace M Bertossi L Roncali 2002 Differential expression of connexin43 in foetal, adult and tumour-associated human brain endothelial cells Histochem J 34 265 271
10. C Foerch I Curdt B Yan F Dvorak M Hermans J Berkefeld 2006 Serum glial fibrillary acidic protein as a biomarker for intracerebral haemorrhage in patients with acute stroke J Neurol Neurosurg Psychiatry 77 181 184
11. B Grobben PP De Deyn H Slegers 2002 Rat C6 glioma as experimental model system for the study of glioblastoma growth and invasion Cell Tissue Res 310 257 270
12. CS Jung C Foerch A Schänzer A Heck KH Plate V Seifert 2007 Serum GFAP is a diagnostic marker for glioblastoma multiforme Brain 130 Pt 12 3336 3341
13. S Leenstra D Troost PK Das N Claessen AE Becker DA Bosch 1993 Endothelial cell marker PAL-E reactivity in brain tumor, developing brain, and brain disease Cancer 72 3061 3067
14. D Moosmayer D Berndorff CH Chang 2006 Bispecific antibody pretargeting of tumor neovasculature for improved systemic radio-therapy of solid tumors Clin Cancer Res 12 5587 5595
15. DA Reardon A Desjardins JN Rich JJ Vredenburgh 2008 The emerging role of anti-angiogenic therapy for malignant glioma Curr Treat Options Oncol 9 1 1 22
16. JH Sampson GE Archer DD Bigner 1999
17. J-C Soria J Fayette J-P Armand 2004 Molecular targeting: targeting angiogenesis in solid tumors Ann Oncol 15 Supplement 4 iv223 iv227
18. Swanson LW (1998) Brain maps structure of the rat brain, 2nd edn. Elsvier, Amsterdam
19. M ter Horst E Brouwer S Verwijnen M Rodijk M de Jong R Hoeben 2007 Targeting malignant gliomas with a glial fibrillary acidic protein (GFAP)-selective oncolytic adenovirus J Gene Med 9 1071 1079
20. J Trojan J-F Cloix M-Y Ardourel 2007 Insulin-like growth factor type I biology and targeting in malignant gliomas Neuroscience 145 795 811
21. Y Yasuda N Tateishi T Shimoda S Satoh E Ogitani S Fujita 2004 Relationship between S100beta and GFAP expression in astrocytes during infarction and glial scar formation after mild transient ischemia Brain Res 1021 1 20 31
22. MR Zalutsky 2005 Current status of therapy of solid tumors: Brain tumor therapy J Nucl Med 46 Suppl 151S 156S
23. MR Zalutsky DA Reardon G Akabani RE Coleman AH Friedman HS Friedman 2008 Clinical experience with a-particle-emitting 211At: treatment of recurrent brain tumor patients with 211At-labeled chimeric antitenascin monoclonal antibody 81C6 J Nucl Med 49 30 38