In-vitro regeneration of sarin inhibited electric eel acetylcholinesterase by bis-pyridinium oximes bearing xylene linker

European Journal of Medicinal Chemistry

Volumn 44, Issue 3, 2009, Pages 1326-1330

  Acharya, Jyotiranjan ^a   Gupta, Arvind Kumar ^a   Mazumder, Avik ^a   Dubey, Devendra Kumar ^a  

^a DEFENCE RESEARCH AND DEVELOPMENT ESTABLISHMENT   (India)

Author keywords

2 PAM; Acetylcholinesterase; Bis pyridinium oximes; Organophosphorus nerve agents; Reactivators; Sarin; Xylene linkers

Indexed keywords

ACETYLCHOLINESTERASE; ANTIDOTE; N,N' 2 XYLENE BIS[(3 HYDROXYIMINOMETHYL)PYRIDINIUM]DIBROMIDE; N,N' 3 XYLENE BIS[(3,3' HYDROXYIMINOMETHYL)PYRIDINIUM]DIBROMIDE; N,N' 4 XYLENE BIS[(2,2' HYDROXYIMINOMETHYL)PYRIDINIUM]DIBROMIDE; N,N' 4 XYLENE BIS[(3,3' HYDROXYIMINOMETHYL)PYRIDINIUM]DIBROMIDE; OBIDOXIME; OXIME; PRALIDOXIME; SARIN; UNCLASSIFIED DRUG; XYLENE;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; EEL; ENZYME REACTIVATION; IN VITRO STUDY; INFRARED RADIATION; PROTON NUCLEAR MAGNETIC RESONANCE;

ANIMALS; CHOLINESTERASE INHIBITORS; ELECTROPHORUS; OXIMES; PYRIDINIUM COMPOUNDS; SARIN; XYLENES;

EID: 60549087001     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.02.020     Document Type: Article

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