The pharmacokinetic profile of recombinant human erythropoietin is unchanged in patients undergoing cardiac surgery

European Journal of Clinical Pharmacology

Volumn 65, Issue 3, 2009, Pages 273-279

  McCluskey, Stuart A ^a,c   Cheung, Wing K ^b   Katznelson, Rita ^a,c   Poonawala, Humara ^a   Fedorko, Ludwik ^a,c   Djaiani, George ^a,c   Mehta, Bobby ^a   Karkouti, Keyvan ^a,c  

^a TORONTO GENERAL HOSPITAL   (Canada)

^b JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Cardiopulmonary bypass; Erythropoietin; Off pump coronary bypass

Indexed keywords

ACETYLSALICYLIC ACID; ERYTHROPOIETIN; FIBRINOGEN; HEMOGLOBIN; HEPARIN; PLACEBO; RECOMBINANT ERYTHROPOIETIN; WARFARIN;

ADULT; AGED; ARTICLE; BLOOD VOLUME; CARDIOPULMONARY BYPASS; CLINICAL ARTICLE; CORONARY ARTERY BYPASS GRAFT; CORONARY ARTERY SURGERY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG DOSE COMPARISON; DRUG METABOLISM; ELECTIVE SURGERY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBRINOGEN BLOOD LEVEL; HEART SURGERY; HEMATOLOGICAL PARAMETERS; HEMOGLOBIN DETERMINATION; HUMAN; INTERNATIONAL NORMALIZED RATIO; MALE; OFF PUMP CORONARY SURGERY; PRIORITY JOURNAL; REPEATED DRUG DOSE; SIDE EFFECT; SINGLE DRUG DOSE; SURGICAL PATIENT; SURVIVAL RATE; THROMBOCYTE COUNT; THROMBOEMBOLISM;

EID: 60549085933     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-008-0575-6     Document Type: Article

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