Case report of four patients with erythrodermic cutaneous T-cell lymphoma and severe photosensitivity mimicking chronic actinic dermatitis

British Journal of Dermatology

Volumn 160, Issue 3, 2009, Pages 698-703

  Agar, N ^a   Morris, S ^b   Russell Jones, R ^a   Hawk, J ^a   Whittaker, S ^a  

^a ST THOMAS HOSPITAL   (United Kingdom)

^b MIDDLESEX HOSPITAL   (United Kingdom)

Author keywords

Chronic actinic dermatitis; Cutaneous T cell lymphoma; Photosensitivity

Indexed keywords

ALPHA INTERFERON; CHLORAMBUCIL; CHLORMETHINE; CORTICOSTEROID; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; DOXORUBICIN; PREDNISOLONE; PREDNISONE; PSORALEN; VINCRISTINE;

ACTINIC KERATOSIS; ADULT; AGED; ARTICLE; BLOOD; CASE REPORT; CD4 CD8 RATIO; CD8+ T LYMPHOCYTE; CELL CLONE; CLINICAL FEATURE; CUTANEOUS T CELL LYMPHOMA; DISEASE SEVERITY; ERYTHRODERMA; HUMAN; IRRADIATION; LOW DRUG DOSE; LYMPH NODE; MALE; PHENOTYPE; PHOTOSENSITIVITY; PRIORITY JOURNAL; PUVA; SEZARY CELL; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; TUMOR CELL; ULTRAVIOLET A RADIATION; ULTRAVIOLET B RADIATION;

AGED; DERMATITIS, EXFOLIATIVE; DIAGNOSIS, DIFFERENTIAL; FATAL OUTCOME; HUMANS; LYMPHOMA, T-CELL, CUTANEOUS; MALE; MIDDLE AGED; PHOTOSENSITIVITY DISORDERS; SKIN NEOPLASMS; ULTRAVIOLET RAYS;

EID: 60449105742     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2008.08955.x     Document Type: Article

References (22)

1. Ive FA, Magnus IA, Warin RP, Jones EW. 'Actinic reticuloid'; a chronic dermatosis associated with severe photosensitivity and the histological resemblance to lymphoma. Br J Dermatol 1969 81 : 469 85.
2. Thomsen K. The development of Hodgkin's disease in a patient with actinic reticuloid. Clin Exp Dermatol 1977 2 : 109 13.
3. Hawk JL. Chronic actinic dermatitis. Photodermatol Photoimmunol Photomed 2004 20 : 312 14.
4. Bilsland D, Crombie IK, Ferguson J. The photosensitivity dermatitis and actinic reticuloid syndrome: no association with lymphoreticular malignancy. Br J Dermatol 1994 131 : 209 14.
5. Fraser-Andrews EA, Woolford AJ, Russell-Jones R et al. Detection of a peripheral blood T-cell clone is an independent prognostic marker in mycosis fungoides. J Invest Dermatol 2000 114 : 117 21.
6. Whittaker SJ, Smith NP, Jones RR, Luzzatto L. Analysis of beta, gamma, and delta T-cell receptor genes in mycosis fungoides and Sézary syndrome. Cancer 1991 68 : 1572 82.
7. Rietschel RL, Fowler JF. Chapter 2. The role of patch testing. In : Fisher's Contact Dermatitis (Rietsdal RL, Fowler JF, eds 4th edn. Baltimore, MD : Williams and Wilkins, 1995 29.
8. Toonstra J, van der Putte SC, van Wichen DF et al. Actinic reticuloid: immunohistochemical analysis of the cutaneous infiltrate in 13 patients. Br J Dermatol 1989 120 : 779 86.
9. Chu AC, Robinson D, Hawk JL et al. Immunologic differentiation of the Sézary syndrome due to cutaneous T-cell lymphoma and chronic actinic dermatitis. J Invest Dermatol 1986 86 : 134 7.
10. Berti E, Tomasini D, Vermeer MH et al. Primary cutaneous CD8-positive epidermotropic cytotoxic T-cell lymphomas. A distinct clinicopathological entity with an aggressive clinical behavior. Am J Pathol 1999 155 : 483 92.
11. Diss TC, Watts M, Pan LX et al. The polymerase chain reaction in the demonstration of monoclonality in T-cell lymphomas. J Clin Pathol 1995 48 : 1045 50.
12. Bakels V, van Oostveen JW, Preesman AH et al. Differentiation between actinic reticuloid and cutaneous T-cell lymphoma by T-cell receptor gamma gene rearrangement analysis and immunophenotyping. J Clin Pathol 1998 51 : 154 8.
13. Menage HP, Ross JS, Norris PG et al. Analysis of T-cell receptor genes in chronic actinic dermatitis: no evidence of clonality. J Invest Dermatol 1992 98 : 546 Abstract).
14. Iwatsuki K. Clone negative CD8 positive Sézary syndrome - a prominent leukemic variant of erythrodermic actinic reticuloid. In : Cutaneous Lymphomas (Burg G, Leboit PE, eds). Darmstadt : Steinkopff Verlag, 2001 32 3.
15. De Silva BD, McLaren K, Kavanagh GM. Photosensitive mycosis fungoides or actinic reticuloid? Br J Dermatol 2000 142 : 1221 7.
16. Ashinoff R, Buchness MR, Lim HW. Lymphoma in a black patient with actinic reticuloid treated with PUVA: possible etiologic considerations. J Am Acad Dermatol 1989 21 : 1134 7.
17. Jensen NE, Sneddon IB. Actinic reticuloid with lymphoma. Br J Dermatol 1970 82 : 286 9.
18. Volden G, Thune PO. Light sensitivity in mycosis fungoides. Br J Dermatol 1977 97 : 279 84.
19. Ive FA. Mycosis fungoides presenting as light sensitivity. Br J Dermatol 1964 76 : 145.
20. Toonstra J, van Weelden H, Gmelig Meyling FH et al. Actinic reticuloid simulating Sézary syndrome. Report of two cases. Arch Dermatol Res 1985 277 : 159 66.
21. Sugita K, Shimauchi T, Tokura Y. Chronic actinic dermatitis associated with adult T-cell leukemia. J Am Acad Dermatol 2005 52 (2 Suppl. 1 38 40.
22. Menage HD, Harrison GI, Potten CS et al. The action spectrum for induction of chronic actinic dermatitis is similar to that for sunburn inflammation. Photochem Photobiol 1995 62 : 976 9.