Hepatocarcinogenic susceptibility of rasH2 mice to troglitazone in a two-stage hepatocarcinogenesis model

Archives of Toxicology

Volumn 83, Issue 2, 2009, Pages 173-181

  Jin, Meilan ^a,b   Saekusa, Yukie ^a,c   Dewa, Yasuaki ^a,c   Nishimura, Jihei ^a,c   Matsumoto, Sayaka ^a,c   Shibutani, Makoto ^a   Hasumi, Keiji ^b   Mitsumori, Kunitoshi ^a  

^a TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

^b TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

^c GIFU UNIVERSITY   (Japan)

Author keywords

PPAR agonist; RasH2 mouse; Troglitazone

Indexed keywords

CYCLINE; DIETHYLNITROSAMINE; GAMMA GLUTAMYLTRANSFERASE; MITOGEN ACTIVATED PROTEIN KINASE; RNA; TROGLITAZONE; VASCULOTROPIN; VASCULOTROPIN B;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEMALE; HISTOLOGY; IMMUNOHISTOCHEMISTRY; LIVER CARCINOGENESIS; LIVER CARCINOMA; LIVER WEIGHT; MALE; NONHUMAN; PARTIAL HEPATECTOMY; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEX DIFFERENCE; SURVIVAL RATE;

ANIMALS; BODY WEIGHT; CARCINOGENS; CHROMANS; DISEASE MODELS, ANIMAL; DISEASE SUSCEPTIBILITY; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GAMMA-GLUTAMYLTRANSFERASE; GENE EXPRESSION REGULATION, NEOPLASTIC; IMMUNOHISTOCHEMISTRY; LIVER NEOPLASMS, EXPERIMENTAL; MALE; MICE; MICE, TRANSGENIC; ORGAN SIZE; PRECANCEROUS CONDITIONS; SURVIVAL ANALYSIS; THIAZOLIDINEDIONES; TIME FACTORS; TUMOR MARKERS, BIOLOGICAL;

MUS;

EID: 60449105696     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-008-0335-5     Document Type: Article

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