Calcium sensitive non-selective cation current promotes seizure-like discharges and spreading depression in a model neuron

Journal of Computational Neuroscience

Volumn 26, Issue 1, 2009, Pages 139-147

  Somjen, G G ^a   Kager, H ^b   Wadman, W J ^b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Calcium dependent current; Calcium depletion; Epilepsy; Non specific cation current; Seizure mechanisms; Spreading depression

Indexed keywords

CALCIUM; CHEMICAL ACTIVATION; ENZYME ACTIVITY; POSITIVE IONS;

'CURRENT; CA 2+; CALCIUM DEPLETION; CALCIUM-DEPENDENT CURRENTS; DISCHARGE DEPRESSION; EPILEPSY; EXTRACELLULAR; NON-SPECIFIC CATION CURRENT; SEIZURE MECHANISM; SPREADING DEPRESSION;

NEURONS;

CALCIUM CHANNEL; CALCIUM ION; CHLORIDE ION; ION CHANNEL; POTASSIUM ION; SODIUM ION;

ACTION POTENTIAL; AFTERDISCHARGE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM CURRENT; CALCIUM SENSITIVE NONSELECTIVE CATION CURRENT; COMPUTER MODEL; EPILEPSY; EPILEPTIC DISCHARGE; EXTRACELLULAR CALCIUM; ION CURRENT; ION TRANSPORT; MEMBRANE DEPOLARIZATION; NERVE CELL; NERVE CELL MEMBRANE; PRIORITY JOURNAL; SEIZURE; SPREADING CORTICAL DEPRESSION;

EID: 60449097719     PISSN: 09295313     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10827-008-0103-9     Document Type: Article

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